Activity of Plazomicin against Gram-negative and Gram-positive Bacterial Pathogens Isolated from Patients in Canadian Hospitals from 2013 to 2017: CANWARD Surveillance Study

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Activity of Plazomicin against Gram-negative and Gram-positive Bacterial Pathogens Isolated from Patients in Canadian Hospitals from 2013 to 2017: CANWARD Surveillance Study is …
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scholarly articleQ13442814

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P356DOI10.1128/AAC.02068-18
P932PMC publication ID6325181
P698PubMed publication ID30373806

P50authorGeorge G ZhanelQ87082624
James A. KarlowskyQ88392142
P2093author name stringGeorge G Zhanel
Andrew Walkty
Heather J Adam
Melanie R Baxter
P2860cites workMultidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistanceQ29617469
Synthesis and spectrum of the neoglycoside ACHN-490Q34134992
Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacinQ34269044
Plazomicin: an investigational therapy for the treatment of urinary tract infections.Q34673393
Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA MethyltransferasesQ36930694
ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolatesQ37392705
Plazomicin Activity against 346 Extended-Spectrum-β-Lactamase/AmpC-Producing Escherichia coli Urinary Isolates in Relation to Aminoglycoside-Modifying EnzymesQ37612977
Detection of methyltransferases conferring high-level resistance to aminoglycosides in enterobacteriaceae from Europe, North America, and Latin AmericaQ42111977
Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitalsQ43762226
Antimicrobial activity of plazomicin against Enterobacteriaceae-producing carbapenemases from 50 Brazilian medical centersQ46244641
Efficacy and Safety of Plazomicin Compared with Levofloxacin in the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis: A Multicenter, Randomized, Double-Blind, Phase 2 StudyQ49598865
Plazomicin activity against polymyxin-resistant Enterobacteriaceae, including MCR-1-producing isolatesQ49934971
In vitro activity of plazomicin against β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE).Q52841787
High prevalence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacteriaceae in the UK & Ireland.Q53700318
Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.Q54205904
Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York CityQ82736865
In Vitro Activity of Plazomicin against Gram-Negative and Gram-Positive Isolates Collected from U.S. Hospitals and Comparative Activities of Aminoglycosides against Carbapenem-Resistant Enterobacteriaceae and Isolates Carrying Carbapenemase GenesQ88984613
Activity of plazomicin compared with other aminoglycosides against isolates from European and adjacent countries, including Enterobacteriaceae molecularly characterized for aminoglycoside-modifying enzymes and other resistance mechanismsQ91467924
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectplazomicinQ15426988
P577publication date2018-12-21
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleIn Vitro Activity of Plazomicin against Gram-Negative and Gram-Positive Bacterial Pathogens Isolated from Patients in Canadian Hospitals from 2013 to 2017 as Part of the CANWARD Surveillance Study
P478volume63

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cites work (P2860)
Q89864930Activity of Plazomicin Tested against Enterobacterales Isolates Collected from U.S. Hospitals (2016-2017): Effect of Different Breakpoint Criteria on in the Susceptibility Rates among Aminoglycosides
Q99580010Plazomicin: a new aminoglycoside in the fight against antimicrobial resistance

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