Dexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model

scientific article published on 29 October 2018

Dexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00540-018-2568-7
P698PubMed publication ID30374889

P2093author name stringAtsushi Kobayashi
Hiroshi Makino
Soichiro Mimuro
Takasumi Katoh
Kensuke Kobayashi
Yoshiki Nakajima
Matsuyuki Doi
Shingo Kawashima
Tsunehisa Sato
P2860cites workHeat strokeQ74327671
The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat heartsQ80056320
Dexmedetomidine administration before, but not after, ischemia attenuates intestinal injury induced by intestinal ischemia-reperfusion in ratsQ83646576
Heat strokeQ88927617
Electrical vagus nerve stimulation attenuates systemic inflammation and improves survival in a rat heatstroke modelQ21133675
Effects of Dexmedetomidine on Intestinal Microcirculation and Intestinal Epithelial Barrier in Endotoxemic Rats.Q35998265
The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidineQ36396296
The impact of the glycocalyx on microcirculatory oxygen distribution in critical illnessQ37421240
Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potentialQ37750085
Implications of recent accumulating knowledge about endothelial glycocalyx on anesthetic managementQ38235924
Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis: A Randomized Clinical TrialQ38379247
Dexmedetomidine Protects Against Multi-Organ Dysfunction Induced by Heatstroke via Sustaining The Intestinal IntegrityQ39607092
Structural Behavior of the Endothelial Glycocalyx Is Associated With Pathophysiologic Status in Septic Mice: An Integrated Approach to Analyzing the Behavior and Function of the Glycocalyx Using Both Electron and Fluorescence Intravital MicroscopyQ40212735
Dexmedetomidine attenuates the microcirculatory derangements evoked by experimental sepsisQ41701807
Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemiaQ42519962
Three-dimensional ultrastructure of capillary endothelial glycocalyx under normal and experimental endotoxemic conditionsQ42654415
Deterioration of myocardial injury due to dexmedetomidine administration after myocardial ischaemiaQ42910158
Evaluation of the hypnotic and hemodynamic effects of dexmedetomidine on propofol-sedated swineQ43059342
Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in ratsQ44929459
Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in ratsQ46441475
Glycocalyx degradation causes microvascular perfusion failure in the ex vivo perfused mouse lung: hydroxyethyl starch 130/0.4 pretreatment attenuates this response.Q50502352
Effects of vasopressin, norepinephrine, and L-arginine on intestinal microcirculation in endotoxemia.Q51809724
Ultrastructural Alteration of Pulmonary Capillary Endothelial Glycocalyx During Endotoxemia.Q52689851
Sepsis and Endothelial PermeabilityQ59227670
A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma PatientsQ61783747
The endothelial glycocalyx protects against myocardial edemaQ73127923
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectdexmedetomidineQ412133
glycocalyxQ898356
P304page(s)880-885
P577publication date2018-10-29
P1433published inJournal of AnesthesiaQ2308373
P1476titleDexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model
P478volume32