High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population

scientific article published on 29 October 2018

High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41591-018-0204-6
P698PubMed publication ID30374197

P50authorPetra ReinkeQ62091040
Hans-Dieter VolkQ84015469
Leila AminiQ85651000
Dimitrios L WagnerQ88139149
Lisa-Marie BurkhardtQ92657041
P2093author name stringLevent Akyüz
Desiree J Wendering
Michael Schmueck-Henneresse
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Molecular mimicry in the autoimmune pathogenesis of rheumatic heart diseaseQ34491035
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Q34507554
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Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificitiesQ35850673
Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct mannersQ36018275
Diversity and evolution of class 2 CRISPR-Cas systemsQ36256836
TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40Q37197918
Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cellsQ37414711
A multifunctional AAV-CRISPR-Cas9 and its host responseQ37731772
How to use antistreptolysin O titre.Q38183799
IMGT/JunctionAnalysis: the first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONsQ38521750
Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.Q38662974
Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in HumansQ39257312
Peripheral blood-derived virus-specific memory stem T cells mature to functional effector memory subsets with self-renewal potencyQ41008417
Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi.Q43733156
Virus treatment questioned after gene therapy deathQ45746742
Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytesQ45771097
Immunity to CRISPR Cas9 and Cas12a therapeuticsQ45873745
HCMV-specific T-cell therapy: do not forget supply of help.Q45990164
DNA methylation controls Foxp3 gene expressionQ46391168
A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg.Q52886049
Direct access to CD4+ T cells specific for defined antigens according to CD154 expression.Q52936537
“Dirty little secrets”—Endotoxin contamination of recombinant proteinsQ61883733
Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA PopulationQ90727473
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cellsQ90788612
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus pyogenesQ131271
Cas9Q16965677
P304page(s)242-248
P577publication date2018-10-29
P1433published inNature MedicineQ1633234
P1476titleHigh prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
P478volume25

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