Dorsal ruffles enhance activation of Akt by growth factors

scientific article published on 16 November 2018

Dorsal ruffles enhance activation of Akt by growth factors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.220517
P932PMC publication ID6262771
P698PubMed publication ID30333140

P50authorLeszek KotulaQ91435698
Catherine SesiQ92365982
Joel A SwansonQ38323409
P2093author name stringSei Yoshida
Regina Pacitto
P2860cites workRagulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acidsQ24306330
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PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes.Q51154659
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Akt regulates growth by directly phosphorylating Tsc2Q29620397
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Sequential signaling in plasma-membrane domains during macropinosome formation in macrophagesQ30489942
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A growth factor signaling cascade confined to circular ruffles in macrophages.Q30528642
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Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathwayQ35213308
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell typesQ35215580
Ruffles limit diffusion in the plasma membrane during macropinosome formationQ35630672
Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophagesQ36356923
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PI3K signaling in cancer: beyond AKT.Q39200710
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Phosphoinositide metabolism during membrane ruffling and macropinosome formation in EGF-stimulated A431 cellsQ40157551
Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.Q40355358
Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, TrioQ41001481
P433issue22
P407language of work or nameEnglishQ1860
P577publication date2018-11-16
P1433published inJournal of Cell ScienceQ1524177
P1476titleDorsal ruffles enhance activation of Akt by growth factors
P478volume131

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cites work (P2860)
Q64067839Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling
Q60952268Macropinosomes as units of signal transduction

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