The PI3K/AKT axis modulates AATF activity in Wilms' tumor cells

The PI3K/AKT axis modulates AATF activity in Wilms' tumor cells is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1002/2211-5463.12500
P932PMC publication ID6168685
P698PubMed publication ID30338213

P2093author name stringPeng Jing
Pei Peng
Jiaqiong Zou
Kegui Weng
P2860cites workIntegration of gene expression and methylation to unravel biological networks in glioblastoma patients.Q39064478
Targeting BCR tyrosine177 site with novel SH2-DED causes selective leukemia cell death in vitro and in vivo.Q39393772
Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemiaQ39692927
Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexesQ47096623
AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancerQ48266870
Position paper: Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocolQ48564189
Kidney cancer: Targeting Wilms tumourQ50173574
Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.Q51136478
Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage ResponseQ87179110
AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosisQ22010860
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosisQ24297172
Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 ProteinsQ26766379
Adult Wilms' tumor - diagnosis and current therapyQ26852264
Wilms' tumor: biology, diagnosis and treatmentQ26862181
Advances in Wilms Tumor Treatment and Biology: Progress Through International CollaborationQ28083988
Functional characterization of AATF transcriptome in human leukemic cellsQ28265783
Wilms' tumor with intravascular extension: A review articleQ34376500
Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signalingQ34644442
Wilms' tumour: connecting tumorigenesis and organ development in the kidneyQ36234726
Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.Q36346917
Che-1/AATF, a multivalent adaptor connecting transcriptional regulation, checkpoint control, and apoptosisQ36916659
eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts.Q37263272
Axl promotes the proliferation, invasion and migration of Wilms' tumor and can be used as a prognostic factorQ37652959
AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1Q38348926
Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cellsQ38955553
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)1615-1623
P577publication date2018-10-01
P1433published inFEBS Open BioQ27724062
P1476titleThe PI3K/AKT axis modulates AATF activity in Wilms' tumor cells
P478volume8

Reverse relations

cites work (P2860)
Q112719524CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity
Q95287534Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription
Q102056663Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma
Q101218379Emerging roles of AATF: Checkpoint signaling and beyond
Q90216185Link between spermine oxidase and apoptosis antagonizing transcription factor: A new pathway in neuroblastoma
Q90664063RNA-Sequencing, Connectivity Mapping, and Molecular Docking to Investigate Ligand-Protein Binding for Potential Drug Candidates for the Treatment of Wilms Tumor

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