Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging

scientific article published on 01 October 2018

Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/AGING.101599
P932PMC publication ID6224265
P698PubMed publication ID30362963

P50authorFrancesca CasciaroQ64216160
P2093author name stringJames A McCubrey
Sandra Marmiroli
Francesca Beretti
Manuela Zavatti
Tullia Maraldi
Matilde Y Follo
Stefano Ratti
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Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescenceQ46354925
NADPH oxidase-4 and MATER expressions in granulosa cells: Relationships with ovarian agingQ46503022
Trajectories and nuclear arrangement of PML bodies are influenced by A-type lamin deficiency.Q48794834
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Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence.Q53542805
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Aging and replicative senescence have related effects on human stem and progenitor cellsQ33464937
Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cellQ33657305
Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patientsQ33724682
Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesisQ34457223
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Regulation of Stem Cell Fate by ROS-mediated Alteration of MetabolismQ35653660
iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis.Q35661127
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Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fatesQ36191257
Oxydative stress alters nuclear shape through lamins dysregulation: a route to senescenceQ36328105
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Sp1 transcription factor interaction with accumulated prelamin a impairs adipose lineage differentiation in human mesenchymal stem cells: essential role of sp1 in the integrity of lipid vesiclesQ36861511
PML, SUMOylation, and SenescenceQ36981640
Inhibition of nuclear Nox4 activity by plumbagin: effect on proliferative capacity in human amniotic stem cellsQ37486972
Oxidative status predicts quality in human mesenchymal stem cellsQ37566969
The nuclear envelope and its involvement in cellular stress responses.Q37958980
Lamins as mediators of oxidative stress.Q38005898
Nuclear damages and oxidative stress: new perspectives for laminopathiesQ38077664
Concise review: optimizing expansion of bone marrow mesenchymal stem/stromal cells for clinical applicationsQ38200506
Effect of hypoxia on human adipose-derived mesenchymal stem cells and its potential clinical applications.Q38754669
Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasisQ38989724
Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type laminsQ39751398
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathwayQ39992451
Cytoplasm-localized SIRT1 enhances apoptosisQ40129938
Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblastsQ40514053
Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected PregnancyQ41543453
MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation.Q41601030
Human amniotic fluid stem cells seeded in fibroin scaffold produce in vivo mineralized matrixQ42016149
Nuclear Nox4 Role in Stemness Power of Human Amniotic Fluid Stem CellsQ42428150
SUMO1 negatively regulates reactive oxygen species production from NADPH oxidasesQ42529820
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2911-2934
P577publication date2018-10-01
P1433published inAgingQ2845875
P1476titleNuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging
P478volume10

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cites work (P2860)
Q92504487New Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach
Q91790750Psychological Stress and Cellular Aging in Cancer: A Meta-Analysis
Q89805787Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology

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