| P50 | author | Martha Lappas | Q59694807 |
| | Stella Liong | Q37384832 |
| P2093 | author name string | Gillian Barker | |
| P2860 | cites work | The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway | Q24294986 |
| | The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation | Q24616946 |
| | Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice | Q27438116 |
| | Proteins regulating Ras and its relatives | Q28257295 |
| | Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 | Q29617043 |
| | The maternal womb: a novel target for cancer prevention in the era of the obesity pandemic? | Q30404178 |
| | Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers | Q33267759 |
| | Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies | Q33291574 |
| | The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells | Q33587770 |
| | Maternal obesity, inflammation, and developmental programming. | Q33747395 |
| | Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways. | Q33888360 |
| | Clinical relevance of KRAS in human cancers | Q33959887 |
| | Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development | Q33967144 |
| | Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity | Q33976401 |
| | Maternal gestational weight gain and offspring weight in adolescence | Q34402636 |
| | Obesity and diabetes in the developing world--a growing challenge | Q34603178 |
| | Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta | Q34824188 |
| | Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions | Q34943207 |
| | Chemical biology tools for regulating RAS signaling complexity in space and time | Q35264345 |
| | RAF1 is increased in labouring myometrium and modulates inflammation-induced pro-labour mediators. | Q53194890 |
| | Activation of NF-kappaB is a novel target of KRAS-induced endometrial carcinogenesis. | Q53289113 |
| | Ras oncogene and inflammation: partners in crime. | Q53674703 |
| | Maternal obesity and pregnancy outcome: a study of 287 213 pregnancies in London | Q57523561 |
| | H-Ras signals to cytoskeletal machinery in induction of integrin-mediated adhesion of T cells | Q73202039 |
| | Mitogen-activated protein kinase proteins regulate LPS-stimulated release of pro-inflammatory cytokines and prostaglandins from human gestational tissues | Q80157675 |
| | Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis | Q80998934 |
| | Maternal obesity and markers of inflammation in pregnancy | Q84021918 |
| | The NR4A receptors Nurr1 and Nur77 are increased in human placenta from women with gestational diabetes | Q85271008 |
| | Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction | Q86826605 |
| | Maternal diabetes in pregnancy: early and long-term outcomes on the offspring and the concept of "metabolic memory" | Q35579461 |
| | An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. | Q35858071 |
| | TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling | Q36247991 |
| | Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial. | Q36428213 |
| | Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. | Q36508970 |
| | Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term | Q36592386 |
| | Cigarette smoking and colorectal cancer risk by KRAS mutation status among older women | Q36656445 |
| | Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation | Q36772844 |
| | The effect of maternal obesity on the offspring | Q36887493 |
| | Apelin is decreased with human preterm and term labor and regulates prolabor mediators in human primary amnion cells | Q37019981 |
| | Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome | Q37091901 |
| | Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study | Q37340755 |
| | Weight status in the first 6 months of life and obesity at 3 years of age | Q37386768 |
| | Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer | Q37610817 |
| | Maternal obesity is associated with a lipotoxic placental environment | Q37689149 |
| | TREM-1 expression is increased in human placentas from severe early-onset preeclamptic pregnancies where it may be involved in syncytialization | Q37699280 |
| | KRAS-induced actin-interacting protein: a potent target for obesity, diabetes and cancer | Q37923195 |
| | The risk of maternal obesity to the long-term health of the offspring | Q38046263 |
| | Obesity and Placental Function. | Q38687952 |
| | Inflammation as a driver and vulnerability of KRAS mediated oncogenesis | Q38864070 |
| | Future predictions of body mass index and overweight prevalence in Australia, 2005-2025. | Q39738391 |
| | The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation | Q39958892 |
| | Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. | Q40105282 |
| | Placental Pim-1 expression is increased in obesity and regulates cytokine- and toll-like receptor-mediated inflammation. | Q40208726 |
| | The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity | Q40399733 |
| | Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen. | Q40540260 |
| | Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas | Q40858455 |
| | Sounding the alarm: protein kinase cascades activated by stress and inflammation | Q41106742 |
| | Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53. | Q42208993 |
| | PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes | Q42381281 |
| | Cancer: Drug for an 'undruggable' protein | Q42734596 |
| | Glucose-induced release of tumour necrosis factor-alpha from human placental and adipose tissues in gestational diabetes mellitus | Q43795799 |
| | Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium. | Q44575859 |
| | Placental structure and inflammation in pregnancies associated with obesity. | Q46328759 |
| | Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar). | Q46916966 |
| | New prognostic factors and calculators for outcome prediction in patients with recurrent glioblastoma: a pooled analysis of EORTC Brain Tumour Group phase I and II clinical trials. | Q47959541 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | obesity | Q12174 |
| | immunology | Q101929 |
| | maternal obesity | Q108582152 |
| P304 | page(s) | 3645386 | |
| P577 | publication date | 2018-10-08 | |
| P1433 | published in | Mediators of Inflammation | Q2144494 |
| P1476 | title | Placental Ras Regulates Inflammation Associated with Maternal Obesity | |
| P478 | volume | 2018 | |