JAK2/STAT3/BMP-2 axis and NF-κB pathway are involved in erythropoietin-induced calcification in rat vascular smooth muscle cells

scientific article published on 07 November 2018

JAK2/STAT3/BMP-2 axis and NF-κB pathway are involved in erythropoietin-induced calcification in rat vascular smooth muscle cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10157-018-1666-Z
P698PubMed publication ID30406500

P2093author name stringLin Zhao
Jin He
Hua Gan
Xiaoyi Zhong
P2860cites workTransforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.Q40404500
The role of tyrosine phosphorylation in proliferation and maturation of erythroid progenitor cells--signals emanating from the erythropoietin receptorQ41659068
Clinical epidemiology of cardiovascular disease in chronic renal diseaseQ43631482
Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney diseaseQ43700932
Oxidative stress modulates osteoblastic differentiation of vascular and bone cellsQ43702897
Modulation of the erythropoietin-induced proliferative pathway by cAMP in vascular smooth muscle cells.Q44207547
Skeletal effects of erythropoietin in hemodialysis patientsQ44908503
Erythropoietin increases cytosolic free calcium concentration in vascular smooth muscle cells.Q64900894
Direct effect of erythropoietin on rat vascular smooth-muscle cell via a putative erythropoietin receptorQ71163676
Human recombinant erythropoietin inhibits interleukin-1beta-stimulated nitric oxide and cyclic guanosine monophosphate production in cultured rat vascular smooth-muscle cellsQ77292152
Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosisQ82222068
Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivoQ83517528
Elastin degradation accelerates phosphate-induced mineralization of vascular smooth muscle cellsQ84638023
Pulse wave velocity and vascular calcification at different stages of chronic kidney diseaseQ84933519
Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHoxQ30471070
Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathwayQ33180653
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?Q33345061
Erythropoietin couples hematopoiesis with bone formationQ33594296
JAK2/STAT5/Bcl-xL signalling is essential for erythropoietin-mediated protection against apoptosis induced in PC12 cells by the amyloid β-peptide Aβ25-35.Q33842736
EPO promotes bone repair through enhanced cartilaginous callus formation and angiogenesisQ33864364
Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomesQ33985838
Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascadesQ34086191
TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify.Q34145009
A current understanding of vascular calcification in CKD.Q34355897
Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney diseaseQ34755816
Direct effects of phosphate on vascular cell functionQ34910006
Erythropoietin promotes bone formation through EphrinB2/EphB4 signalingQ35106750
Erythropoietin (EPO) in acute kidney injuryQ35176135
The Addition of Vascular Calcification Scores to Traditional Risk Factors Improves Cardiovascular Risk Assessment in Patients with Chronic Kidney DiseaseQ35693460
Dual Delivery of EPO and BMP2 from a Novel Modular Poly-ɛ-Caprolactone Construct to Increase the Bone Formation in Prefabricated Bone FlapsQ36006827
Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expressionQ36035490
Role of matrix Gla protein in angiotensin II-induced exacerbation of vascular calcificationQ36309309
The mechanism of erythropoietin actionQ36433253
Dose of erythropoiesis-stimulating agents and adverse outcomes in CKD: a metaregression analysisQ36476556
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.Q36678487
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecterythropoietinQ218706
NF-κBQ411114
P304page(s)501-512
P577publication date2018-11-07
P1433published inClinical and experimental nephrologyQ26842022
P1476titleJAK2/STAT3/BMP-2 axis and NF-κB pathway are involved in erythropoietin-induced calcification in rat vascular smooth muscle cells
P478volume23

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