| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Frank Tacke | |
| Jana Hundertmark | |||
| Oliver Krenkel | |||
| P2860 | cites work | The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism | Q24337667 |
| GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects | Q24630455 | ||
| Adipose tissue macrophages: going off track during obesity | Q26768692 | ||
| Macrophages in intestinal homeostasis and inflammation | Q26851960 | ||
| Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury | Q27334890 | ||
| Structural basis for the activation of PPARgamma by oxidized fatty acids | Q27653525 | ||
| An obesity-associated gut microbiome with increased capacity for energy harvest | Q27860515 | ||
| Metabolic reprogramming in macrophages and dendritic cells in innate immunity | Q28080815 | ||
| Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance | Q28131660 | ||
| Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens. | Q39735658 | ||
| TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess | Q39817074 | ||
| A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis. | Q40082820 | ||
| Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis. | Q40608400 | ||
| Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function | Q40687846 | ||
| A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair. | Q40721153 | ||
| Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury | Q41071492 | ||
| FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis | Q41107620 | ||
| Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study | Q41319267 | ||
| CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy. | Q41334568 | ||
| Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8. | Q41600153 | ||
| Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. | Q41644055 | ||
| Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases | Q41750314 | ||
| Cross talk of the immune system in the adipose tissue and the liver in non-alcoholic steatohepatitis: Pathology and beyond. | Q41821872 | ||
| Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. | Q41912120 | ||
| Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis | Q42111412 | ||
| Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD. | Q42172913 | ||
| A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity | Q42257294 | ||
| Adipose-derived circulating miRNAs regulate gene expression in other tissues | Q42319316 | ||
| Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation | Q42339950 | ||
| Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice | Q42351778 | ||
| Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease | Q42580307 | ||
| M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease | Q42710363 | ||
| Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. | Q42729920 | ||
| Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance. | Q42805774 | ||
| The role of the gut microbiota in nonalcoholic fatty liver disease | Q42838234 | ||
| Intestinal flora imbalance results in altered bacterial translocation and liver function in rats with experimental cirrhosis | Q42925588 | ||
| Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity | Q43200840 | ||
| HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products | Q43248408 | ||
| Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity | Q43519786 | ||
| Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease | Q43761846 | ||
| Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity | Q44687051 | ||
| Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation | Q44752269 | ||
| No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial | Q44997998 | ||
| The ASK1 Inhibitor Selonsertib in Patients with Nonalcoholic Steatohepatitis: A Randomized, Phase 2 Trial | Q45067109 | ||
| Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention | Q45067817 | ||
| Therapeutic Inhibition of Inflammatory Monocyte Recruitment Reduces Steatohepatitis and Liver Fibrosis | Q45872331 | ||
| The inflammasome in liver disease | Q46090929 | ||
| Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial | Q46216843 | ||
| Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling | Q38323825 | ||
| Immunoregulation by lipids during the development of non-alcoholic steatohepatitis | Q38365029 | ||
| DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery | Q38487123 | ||
| Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes | Q38603408 | ||
| Oxidative and ER stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury. | Q38663842 | ||
| Immunology in the liver--from homeostasis to disease | Q38693925 | ||
| Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes. | Q38803828 | ||
| CD44 is a key player in non-alcoholic steatohepatitis | Q38890869 | ||
| Role of lipids in the metabolism and activation of immune cells | Q38899326 | ||
| Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis | Q39049164 | ||
| IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet | Q39077154 | ||
| Targeting hepatic macrophages to treat liver diseases | Q39166232 | ||
| Liver macrophages in tissue homeostasis and disease | Q39187324 | ||
| Release of chromatin protein HMGB1 by necrotic cells triggers inflammation | Q28131815 | ||
| HMG-1 as a late mediator of endotoxin lethality in mice | Q28139166 | ||
| Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial | Q28253122 | ||
| Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver | Q28389108 | ||
| Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity | Q28512778 | ||
| NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals | Q29615704 | ||
| Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling | Q29616024 | ||
| The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance | Q29616026 | ||
| HIF-1alpha is essential for myeloid cell-mediated inflammation | Q29617581 | ||
| C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus | Q29619398 | ||
| Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria | Q29619620 | ||
| Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis | Q29619888 | ||
| Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance | Q30009848 | ||
| Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening | Q30277347 | ||
| NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice | Q30277911 | ||
| Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. | Q30375693 | ||
| Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production | Q30416248 | ||
| Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis | Q30538670 | ||
| Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner | Q30701525 | ||
| Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota | Q33685907 | ||
| Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity | Q33724394 | ||
| IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge | Q33910916 | ||
| Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis | Q34036872 | ||
| The importance of GLUT3 for de novo lipogenesis in hypoxia-induced lipid loading of human macrophages | Q34372598 | ||
| Omega-3 polyunsaturated fatty acids antagonize macrophage inflammation via activation of AMPK/SIRT1 pathway | Q34446920 | ||
| Short-Chain Fatty Acids Protect Against High-Fat Diet-Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation | Q34463631 | ||
| Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling | Q34491604 | ||
| Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice. | Q34496310 | ||
| Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice | Q34533851 | ||
| Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH. | Q35014238 | ||
| The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis | Q35056726 | ||
| Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death | Q35061420 | ||
| Therapy of experimental NASH and fibrosis with galectin inhibitors | Q35075568 | ||
| TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation | Q35173133 | ||
| Alterations of the human gut microbiome in liver cirrhosis | Q35216354 | ||
| Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease. | Q35242565 | ||
| CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis | Q35692948 | ||
| Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 | Q36042132 | ||
| Kupffer Cells Undergo Fundamental Changes during the Development of Experimental NASH and Are Critical in Initiating Liver Damage and Inflammation | Q36084822 | ||
| Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD | Q36228033 | ||
| Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice | Q36243894 | ||
| Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. | Q36339484 | ||
| Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase | Q36377312 | ||
| Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice | Q36592306 | ||
| Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis | Q36681112 | ||
| Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors | Q36775202 | ||
| Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease. | Q36796803 | ||
| Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice. | Q36800214 | ||
| NADPH oxidase is implicated in the pathogenesis of oxidative phosphorylation dysfunction in mice fed a high-fat diet. | Q36898694 | ||
| Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation | Q37040183 | ||
| A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis | Q37091511 | ||
| Toll-like receptors and adaptor molecules in liver disease: update | Q37174620 | ||
| Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages | Q37222666 | ||
| JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation | Q37330051 | ||
| Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice | Q37355594 | ||
| Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis | Q37362066 | ||
| Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype | Q37372606 | ||
| Kupffer cells mediate leptin-induced liver fibrosis | Q37375470 | ||
| Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice | Q37465299 | ||
| MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet | Q37476440 | ||
| Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. | Q37635856 | ||
| A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse | Q37649853 | ||
| Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver disease | Q37704752 | ||
| The sterile inflammatory response | Q37716003 | ||
| Regulation of the immune system by the resident intestinal bacteria. | Q37716899 | ||
| Sterile inflammation in the liver | Q38043897 | ||
| Sterols and oxysterols in immune cell function | Q38130108 | ||
| Roles for chemokines in liver disease | Q38234487 | ||
| Shaping macrophages function and innate immunity by bile acids: mechanisms and implication in cholestatic liver diseases | Q38245190 | ||
| NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. | Q46228637 | ||
| Quercetin and Ascorbic Acid Suppress Fructose-Induced NLRP3 Inflammasome Activation by Blocking Intracellular Shuttling of TXNIP in Human Macrophage Cell Lines | Q46399998 | ||
| Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis | Q46648168 | ||
| CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance | Q46828201 | ||
| Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex. | Q47139181 | ||
| Nonalcoholic Fatty Liver Disease Is Exacerbated in High-Fat Diet-Fed Gnotobiotic Mice by Colonization with the Gut Microbiota from Patients with Nonalcoholic Steatohepatitis | Q47430306 | ||
| Lipotoxicity and the gut-liver axis in NASH pathogenesis. | Q47444988 | ||
| Genetics and epigenetics of NAFLD and NASH: Clinical impact | Q47623021 | ||
| Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial. | Q47765250 | ||
| Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese | Q48296229 | ||
| S100 Proteins As an Important Regulator of Macrophage Inflammation. | Q49497885 | ||
| Immune neutralization of the receptor for advanced glycation endproducts reduce liver oxidative damage induced by an acute systemic injection of lipopolysaccharide. | Q49819884 | ||
| A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84. | Q49896987 | ||
| Cenicriviroc for the treatment of non-alcoholic steatohepatitis and liver fibrosis. | Q49963564 | ||
| Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. | Q50065321 | ||
| Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles. | Q50223846 | ||
| Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. | Q50528458 | ||
| Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. | Q51443610 | ||
| Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. | Q51580928 | ||
| Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury. | Q51702513 | ||
| RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis. | Q51832023 | ||
| Hepatocytes and neutrophils cooperatively suppress bacterial infection by differentially regulating lipocalin-2 and NETs. | Q52690957 | ||
| The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis. | Q52699074 | ||
| Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism. | Q52717686 | ||
| Augmented hepatic Toll-like receptors by fatty acids trigger the pro-inflammatory state of non-alcoholic fatty liver disease in mice. | Q53099275 | ||
| Macrophages in Nonalcoholic Fatty Liver Disease: A Role Model of Pathogenic Immunometabolism. | Q53815227 | ||
| CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis. | Q54154240 | ||
| Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis. | Q54309135 | ||
| Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. | Q54328614 | ||
| Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells. | Q54941585 | ||
| Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. | Q55417436 | ||
| The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice | Q56507986 | ||
| Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women | Q57518109 | ||
| Mechanisms of NAFLD development and therapeutic strategies. | Q59443140 | ||
| Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure | Q60713404 | ||
| Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts | Q61575260 | ||
| Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats | Q61680340 | ||
| Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. | Q64975429 | ||
| Beneficial effects of pentoxifylline on hepatic steatosis, fibrosis and necroinflammation in patients with non-alcoholic steatohepatitis | Q80183305 | ||
| Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis | Q83679148 | ||
| Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice | Q84646403 | ||
| Lactobacillus paracasei Induces M2-Dominant Kupffer Cell Polarization in a Mouse Model of Nonalcoholic Steatohepatitis | Q85529972 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell | Q7868 |
| liver disease | Q929737 | ||
| metabolic dysfunction–associated steatotic liver disease | Q1546498 | ||
| adaptive immune system | Q1645075 | ||
| fatty liver disease | Q6058862 | ||
| myeloid-derived suppressor cells | Q15220362 | ||
| P304 | page(s) | 2418 | |
| P577 | publication date | 2018-01-01 | |
| 2018-10-18 | |||
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | Adapted Immune Responses of Myeloid-Derived Cells in Fatty Liver Disease | |
| P478 | volume | 9 |
| Q93190742 | Characterization of Cellular Sources and Circulating Levels of Extracellular Vesicles in a Dietary Murine Model of Nonalcoholic Steatohepatitis |
| Q97519035 | Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis |
| Q94521535 | DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype |
| Q64946007 | Liver Macrophages: Old Dogmas and New Insights. |
Search more.