Tafenoquine and primaquine do not exhibit clinical neurologic signs associated with central nervous system lesions in the same manner as earlier 8-aminoquinolines

scientific article published on 06 November 2018

Tafenoquine and primaquine do not exhibit clinical neurologic signs associated with central nervous system lesions in the same manner as earlier 8-aminoquinolines is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1186/S12936-018-2555-3
P932PMC publication ID6219089
P698PubMed publication ID30400893

P2093author name stringTracey Brown
Jonathan Berman
Stephen Toovey
Geoffrey Dow
P2860cites workA new primaquine analogue, tafenoquine (WR 238605), for prophylaxis against Plasmodium falciparum malariaQ28204425
Randomized, parallel placebo-controlled trial of primaquine for malaria prophylaxis in Papua, IndonesiaQ31030931
Randomized, double-blind study of the safety, tolerability, and efficacy of tafenoquine versus mefloquine for malaria prophylaxis in nonimmune subjectsQ33613720
Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and meta-analysis.Q33806574
Toxicity of primaquine in CaucasiansQ33975955
Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I.Q33999450
Randomised placebo-controlled trial of primaquine for prophylaxis of falciparum and vivax malaria.Q34288516
Mefloquine induces dose-related neurological effects in a rat modelQ34509705
The nature of relapse in schizophreniaQ34581127
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)Q35181605
THE TOXICITY OF LARGE DOSES OF PENTAQUINE (SN-13,276), A NEW ANTIMALARIAL DRUG.Q35306681
PENTAQUINE (SN-13,276), A THERAPEUTIC AGENT EFFECTIVE IN REDUCING THE RELAPSE RATE IN VIV AX MALARIA.Q35306715
Methamphetamine psychosis: epidemiology and managementQ37265315
Mefloquine neurotoxicity: a literature reviewQ37378828
Tafenoquine for malaria prophylaxis in adults: An integrated safety analysisQ38376925
Tafenoquine is not neurotoxic following supertherapeutic dosing in ratsQ38684922
Drowsiness and motor responses to consecutive daily doses of promethazine and loratadineQ39199497
Relationships between chemical structures of 8-aminoquinolines and their capacities for radical cure of infections with Plasmodium cynomolgi in rhesus monkeysQ42115534
The New Synthetic DrugsQ42347593
Plasmodium cynomolgi infections in the rhesus monkeyQ44167110
The impact of Malarone and primaquine on psychomotor performanceQ44513850
Mefloquine for preventing malaria during travel to endemic areasQ47140318
First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial.Q47831031
Low dosage promethazine and loratadine negatively affect neuromotor functionQ48285616
Plasmocid encephalopathy in the rhesus monkey: a study of selective vulnerabilityQ48649462
Recurrence in affective disorder. I. Case register study.Q50897602
Primaquine, SN 13272, a new curative agent in vivax malaria; a preliminary reportQ56525975
Neurotoxicity of the 8-aminoquinolines. III. The effects of pentaquine, isopentaquine, primaquine, and pamaquine on the central nervous system of the rhesus monkeyQ75803343
Neurotoxicity of the 8-aminoquinolines; lesions in the central nervous system of the rhesus monkey induced by administration of plasmocidQ79498993
Pamaquine poisoning in man, with a clinicopathologic study of one caseQ80378702
Neurotoxicity of the 8-aminoquinolines; reactions of various experimental animals to plasmocidQ80644165
Plasmochin toxicity; analysis of 258 casesQ82143420
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantimalarialQ521616
P304page(s)407
P577publication date2018-11-06
P1433published inMalaria JournalQ15749954
P1476titleTafenoquine and primaquine do not exhibit clinical neurologic signs associated with central nervous system lesions in the same manner as earlier 8-aminoquinolines
P478volume17

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cites work (P2860)
Q90310182Neurological and psychiatric safety of tafenoquine in Plasmodium vivax relapse prevention: a review
Q91845916Visible-Light-Photocatalyzed Reductions of N-Heterocyclic Nitroaryls to Anilines Utilizing Ascorbic Acid Reductant

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