Phosphodiesterase 8A

mammalian protein found in Homo sapiens

Wikidata entity: Q5864340



P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14758909 (G protein-coupled receptor signaling pathway) G protein-coupled receptor signaling pathway
P682 biological process ... Q14819846 (positive regulation of protein phosphorylation) positive regulation of protein phosphorylation
P682 biological process ... Q14819896 (negative regulation of cell death) negative regulation of cell death
P682 biological process ... Q14821388 (positive regulation of ERK1 and ERK2 cascade) positive regulation of ERK1 and ERK2 cascade
P682 biological process ... Q14865575 (cyclic nucleotide metabolic process) cyclic nucleotide metabolic process
P682 biological process ... Q21095692 (cellular response to epidermal growth factor stimulus) cellular response to epidermal growth factor stimulus
P682 biological process ... Q21097311 (negative regulation of hydrogen peroxide-induced cell death) negative regulation of hydrogen peroxide-induced cell death
P682 biological process ... Q21105008 (cAMP catabolic process) cAMP catabolic process
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P591 EC enzyme number String 3.1.4.53 ???
P702 encoded by ... Q18030417 (PDE8A) PDE8A
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24773706 (3'5'-cyclic nucleotide phosphodiesterase, conserved site) 3'5'-cyclic nucleotide phosphodiesterase, conserved site
P527 has part(s) ... Q24773859 (PAS fold) PAS fold
P527 has part(s) ... Q24784686 (PAS domain) PAS domain
P527 has part(s) ... Q24784827 (HD/PDEase domain) HD/PDEase domain
P527 has part(s) ... Q24785962 (3'5'-cyclic nucleotide phosphodiesterase, catalytic domain) 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14353168 (hydrolase activity) hydrolase activity
P680 molecular function ... Q14864244 (kinase binding) kinase binding
P680 molecular function ... Q14865571 (3',5'-cyclic-nucleotide phosphodiesterase activity) 3',5'-cyclic-nucleotide phosphodiesterase activity
P680 molecular function ... Q14865574 (3',5'-cyclic-GMP phosphodiesterase activity) 3',5'-cyclic-GMP phosphodiesterase activity
P680 molecular function ... Q14865583 (phosphoric diester hydrolase activity) phosphoric diester hydrolase activity
P680 molecular function ... Q21106792 (3',5'-cyclic-AMP phosphodiesterase activity) 3',5'-cyclic-AMP phosphodiesterase activity
P361 part of ... Q24772781 (3'5'-cyclic nucleotide phosphodiesterase) 3'5'-cyclic nucleotide phosphodiesterase
P361 part of ... Q41797114 (PAS domain superfamily) PAS domain superfamily
P361 part of ... Q41798063 (3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily) 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
P361 part of ... Q83141287 (PAS fold family) PAS fold family
P361 part of ... Q83164039 (PAS domain, protein family) PAS domain, protein family
P361 part of ... Q83164137 (HD/PDEase domain, protein family) HD/PDEase domain, protein family
P361 part of ... Q83165423 (3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family) 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family
P361 part of ... Q95351042 (3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family) 3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family
P129 physically interacts with ... Q419374 (dipyridamole) dipyridamole
P129 physically interacts with ... Q27106648 (flavoxate hydrochloride) flavoxate hydrochloride

External Ids
P705Ensembl protein IDENSP00000431976
P705Ensembl protein IDENSP00000378056
P705Ensembl protein IDENSP00000311453
P705Ensembl protein IDENSP00000340679
P705Ensembl protein IDENSP00000452907
P705Ensembl protein IDENSP00000454094
P705Ensembl protein IDENSP00000432309
P705Ensembl protein IDENSP00000453808
P2671Google Knowledge Graph ID/g/12214slw
P638PDB structure ID3ECN
P638PDB structure ID3ECM
P637RefSeq protein IDNP_001230066
P637RefSeq protein IDNP_002596
P637RefSeq protein IDNP_775656
P637RefSeq protein IDXP_011519970
P637RefSeq protein IDXP_016877797
P637RefSeq protein IDXP_016877798
P637RefSeq protein IDXP_016877799
P637RefSeq protein IDXP_016877800
P637RefSeq protein IDXP_024305714
P637RefSeq protein IDXP_024305715
P352UniProt protein IDO60658

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