PICOT: A Multidomain Protein with Multiple Functions

PICOT: A Multidomain Protein with Multiple Functions is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.5402/2011/426095

P2093author name stringNoah Isakov
Anna Keselman
Ranjan Nath Pulak
Keren Moyal
P2860cites workInhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domainQ22011055
Characterization of 16 novel human genes showing high similarity to yeast sequencesQ24290660
Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesisQ24309295
PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signalingQ24311991
Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and functionQ24648178
Decreased interactions of mutant muscle LIM protein (MLP) with N-RAP and alpha-actinin and their implication for hypertrophic cardiomyopathyQ28119009
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligationQ28198175
Mutations in the muscle LIM protein and α-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosisQ28211195
Three-dimensional segregation of supramolecular activation clusters in T cellsQ28282528
Localization of protein kinases by anchoring proteins: a theme in signal transductionQ28299903
Selective modulation of protein kinase C-theta during T-cell activationQ28300613
PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretionQ28586641
Differential protein expression at the stage of neural tube closure in the mouse embryo.Q52115563
Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.Q53648105
Preferential overexpression of glutaredoxin3 in human colon and lung carcinoma.Q54462663
A cell-death-defying factor, anamorsin mediates cell growth through inactivation of PKC and p38MAPK.Q54621225
Deciphering a novel thioredoxin-like fold familyQ56999368
Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological SynapseQ57962190
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytesQ58617364
PICOT is a molecule which binds to anamorsinQ28587057
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-discQ28593396
Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responsesQ28594762
Structural classification of thioredoxin-like fold proteins.Q30344339
PICOT is a critical regulator of cardiac hypertrophy and cardiomyocyte contractilityQ30490584
A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis.Q33684671
The role of the redox protein thioredoxin in cell growth and cancerQ34062727
Widespread expression of PICOT in mouse and human tissues with predominant localization to epitheliumQ34076686
Protein kinase Ctheta: a new essential superstar on the T-cell stageQ34091319
Cardiac Z-disc signaling networkQ34160361
MLP (muscle LIM protein) as a stress sensor in the heartQ34177602
The immunological synapse.Q34178149
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signalingQ34428947
Placenta growth factor expression is regulated by hydrogen peroxide in vascular smooth muscle cellsQ34597511
Protein kinase C-theta;: signaling from the center of the T-cell synapseQ34612513
Hydrogen peroxide as second messenger in lymphocyte activationQ35007083
Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKsQ35846936
Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cellsQ36736153
Monothiol glutaredoxins: a common domain for multiple functions.Q36784368
Identification of intracellular receptor proteins for activated protein kinase CQ37505978
Hydrogen peroxide as a cell-survival signaling molecule.Q37532463
Hydrogen peroxide as a signaling moleculeQ37849782
Hodgkin's lymphoma cells exhibit high expression levels of the PICOT proteinQ39737399
PICOT, protein kinase C theta-interacting protein, is a novel regulator of FcepsilonRI-mediated mast cell activationQ39982554
A major, transformation-sensitive PKC-binding protein is also a PKC substrate involved in cytoskeletal remodelingQ41022582
Coordination of three signaling enzymes by AKAP79, a mammalian scaffold proteinQ41216893
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur clusterQ41814139
Direct interaction between p47phox and protein kinase C: evidence for targeting of protein kinase C by p47phox in neutrophilsQ41968271
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha.Q41988723
Sinusoidal endothelium release of hydrogen peroxide enhances very late antigen-4-mediated melanoma cell adherence and tumor cytotoxicity during interleukin-1 promotion of hepatic melanoma metastasis in miceQ42436675
Characterization of the human monothiol glutaredoxin 3 (PICOT) as iron-sulfur proteinQ43131437
Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activationQ43619602
T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylationQ44537867
PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractilityQ45859379
Protein kinase C-theta (PKCtheta) distribution analysis in hematopoietic cells: proliferating T cells exhibit high proportions of PKCtheta in the particulate fractionQ50335811
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)1-7
P577publication date2011-01-01
P1433published inISRN ImmunologyQ50810580
P1476titlePICOT: A Multidomain Protein with Multiple Functions
P478volume2011

Search more.