Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function

scientific article published on 01 August 2018

Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2018.07.084
P932PMC publication ID6172041
P698PubMed publication ID30157439

P50authorCong-Hui YaoQ61468649
Lucas D'SouzaQ88610812
P2093author name stringRyan M Nunley
Deepta Bhattacharya
Gary J Patti
Arijita Jash
Wing Y Lam
Rachel Wong
Gordon P Meares
P2860cites workPlasma cell differentiation requires the transcription factor XBP-1Q24291453
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease familyQ24316388
CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow nicheQ24657562
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Analyzing and interpreting genome data at the network level with ConsensusPathDBQ27887656
Translational control is required for the unfolded protein response and in vivo glucose homeostasisQ28204066
BCMA is essential for the survival of long-lived bone marrow plasma cellsQ28587037
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
Mcl-1 is essential for the survival of plasma cellsQ30412677
Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trialQ30991737
Small molecule inhibitors of the RNA-dependent protein kinaseQ31151292
Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.Q33466491
Adjuvant-specific regulation of long-term antibody responses by ZBTB20Q33569857
Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencingQ33584087
The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infectionsQ33587496
Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein responseQ33838972
Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts.Q33904647
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter DropletsQ34044099
Long-lived bone marrow plasma cells are induced early in response to T cell-independent or T cell-dependent antigensQ34270556
Intracellular fate of 2-NBDG, a fluorescent probe for glucose uptake activity, in Escherichia coli cellsQ34412777
Lasting antibody responses are mediated by a combination of newly formed and established bone marrow plasma cells drawn from clonally distinct precursorsQ34523096
Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrowQ34749203
Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cellsQ35102323
ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane associationQ35214896
Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinaseQ35417754
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.Q35981133
ClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interfaceQ36305105
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gutQ36367288
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survivalQ36368882
Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone MarrowQ36376043
Plasma cell ontogeny defined by quantitative changes in blimp-1 expressionQ36399312
Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoiresQ36468327
A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma CellsQ36494525
Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'.Q36529035
Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein responseQ36591114
Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma CellsQ37116099
Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological ResponsesQ37117337
CD98hc facilitates B cell proliferation and adaptive humoral immunityQ37166768
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cellsQ37181198
mTOR has distinct functions in generating versus sustaining humoral immunity.Q37395797
Pathogenic long-lived plasma cells and their survival niches in autoimmunity, malignancy, and allergyQ38061406
Eukaryotic initiation factor 2alpha phosphorylation is required for B-cell maturation and function in miceQ38289179
Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activityQ38477851
Salmon provides fast and bias-aware quantification of transcript expressionQ38926825
Metabolomics of B to plasma cell differentiationQ39509132
The life span of short-lived plasma cells is partly determined by a block on activation of apoptotic caspases acting in combination with endoplasmic reticulum stress.Q39677206
Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical DevelopmentQ39781089
Blimp-1-dependent and -independent natural antibody production by B-1 and B-1-derived plasma cells.Q40139047
Protein Translation Activity: A New Measure of Host Immune Cell ActivationQ40622871
Studies of the mechanism of tunicamycin in hibition of IgA and IgE secretion by plasma cellsQ40773377
Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cellsQ41056091
The transcriptional profiling of human in vivo-generated plasma cells identifies selective imbalances in monoclonal gammopathiesQ41444022
Measuring ER stress and the unfolded protein response using mammalian tissue culture systemQ41898554
ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.Q41986026
Metabolic Links between Plasma Cell Survival, Secretion, and StressQ41997253
Duration of humoral immunity to common viral and vaccine antigensQ45872621
An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain geneQ46984270
EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody ProductionQ47232451
MiXCR: software for comprehensive adaptive immunity profiling.Q48193977
A new staining protocol for detection of murine antibody-secreting plasma cell subsets by flow cytometryQ48286701
ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism.Q50654661
Protocol for improved resolution of plasma cell subpopulations by flow cytometry.Q50920954
Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.Q50927930
Humoral immunity due to long-lived plasma cells.Q52040025
Cloning and expression of murine Ig genes from single B cells.Q52908841
Survival of long-lived plasma cells is independent of antigen.Q52991819
Plasma cells require autophagy for sustainable immunoglobulin production.Q53122740
Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis.Q53706620
Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells.Q54227237
High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 DeficiencyQ61783451
The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevityQ78346721
Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent AntigenQ89091464
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectlifetimeQ22675021
P304page(s)2479-2492.e6
P577publication date2018-08-01
P1433published inCell ReportsQ5058165
P1476titleMetabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function
P478volume24

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cites work (P2860)
Q59349637Basics of memory B-cell responses: lessons from and for the real world
Q90401160Factors Affecting Early Antibody Secreting Cell Maturation Into Long-Lived Plasma Cells
Q90053427Immune metabolism regulation of the germinal center response
Q95329458Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria
Q93078150Mitochondria as central hub of the immune system
Q114871354Nutraceuticals and Dietary Supplements for Older Adults with Long COVID-19
Q91868748Plasma Cells, the Next Generation: Beyond Antibody Secretion
Q92383022Plasma cells: You are what you eat
Q57054936Plasma cells: the programming of an antibody-secreting machine
Q92203848Programming Isotype-Specific Plasma Cell Function
Q58552434Regulation of metabolic supply and demand during B cell activation and subsequent differentiation
Q64067955Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle
Q64071635The Maintenance of Memory Plasma Cells
Q63740034Virus Control of Cell Metabolism for Replication and Evasion of Host Immune Responses
Q90929866ZBTB32 restrains antibody responses to murine cytomegalovirus infections, but not other repetitive challenges

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