Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

scholarly article by Stefan W Metz et al published September 2018 in PLoS Neglected Tropical Diseases

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PNTD.0006793
P932PMC publication ID6171938
P698PubMed publication ID30248097

P50authorJoseph DeSimoneQ6282541
Stefan W MetzQ61078454
Aravinda M. de SilvaQ89242260
Shaomin TianQ93015620
Katie HorvathQ125314569
Alex BrackbillQ125314691
P2093author name stringMichael J Miley
Chris Luft
Ashlie Thomas
Michele Stone
Yi Xianwen
P2860cites workThe global distribution and burden of dengueQ24628768
From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccineQ24737418
Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika VirusQ26247258
The Complexity of a Dengue Vaccine: A Review of the Human Antibody ResponseQ26995782
A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human PrimatesQ27116692
Comparison of Plaque- and Flow Cytometry-Based Methods for Measuring Dengue Virus NeutralizationQ27484661
Development of a recombinant tetravalent dengue virus vaccine: Immunogenicity and efficacy studies in mice and monkeysQ27491049
Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins.Q54231305
Nanovaccinology: the next generation of vaccines meets 21st century materials science and engineeringQ87446725
WHO recommends additional tests for Sanofi's dengue vaccine after safety concernsQ88426591
Neutralizing Antibody Correlates Analysis of Tetravalent Dengue Vaccine Efficacy Trials in Asia and Latin AmericaQ89453187
Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 VirusesQ27491299
Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody ResponsesQ27493140
Structural insights into the neutralization mechanism of a higher primate antibody against dengue virusQ27675965
A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surfaceQ27681319
Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and VaccinationQ28114614
The Impact of the Newly Licensed Dengue Vaccine in Endemic CountriesQ28354105
Nanoparticles and the immune systemQ33634320
In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-DimersQ33867337
Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic DiseaseQ34487028
Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clonesQ34593818
Potent engineered PLGA nanoparticles by virtue of exceptionally high chemotherapeutic loadingsQ35064955
Immunity in response to particulate antigen-delivery systemsQ35961146
Identification of human neutralizing antibodies that bind to complex epitopes on dengue virionsQ35982791
Dengue vector control strategies in an urban setting: an economic modelling assessmentQ36132072
DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimersQ36352752
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Immune correlates of protection for dengue: State of the art and research agendaQ38652971
Dissecting Antibodies Induced by a Chimeric Yellow Fever-Dengue, Live-Attenuated, Tetravalent Dengue Vaccine (CYD-TDV) in Naive and Dengue-Exposed Individuals.Q38727029
Protective and immunological behavior of chimeric yellow fever dengue vaccineQ38731663
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The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1.Q39186657
Functional analysis of dengue virus (DENV) type 2 envelope protein domain 3 type-specific and DENV complex-reactive critical epitope residuesQ40185205
Purified dengue 2 virus envelope glycoprotein aggregates produced by baculovirus are immunogenic in miceQ40622821
Epitopic analysis of antigenic determinants on the surface of dengue-2 virions using monoclonal antibodiesQ40822411
Antibody-enhanced dengue virus infection in primate leukocytesQ40884212
Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope ProteinQ41921198
Dengue vaccine: hypotheses to understand CYD-TDV-induced protectionQ42985743
Development of a nanoparticle-based influenza vaccine using the PRINT technology.Q44738301
Consider stopping dengvaxia administration without immunological screeningQ48032296
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectnanoparticleQ61231
Dengue virusQ476209
infectious diseaseQ18123741
P304page(s)e0006793
P577publication date2018-09-01
P1433published inPLoS Neglected Tropical DiseasesQ3359737
P1476titleNanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype
P478volume12

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