Relationship of Transmural Variations in Myofiber Contractility to Left Ventricular Ejection Fraction: Implications for Modeling Heart Failure Phenotype With Preserved Ejection Fraction

scientific article published on 24 August 2018

Relationship of Transmural Variations in Myofiber Contractility to Left Ventricular Ejection Fraction: Implications for Modeling Heart Failure Phenotype With Preserved Ejection Fraction is …
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scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2018.01003
P932PMC publication ID6117406
P698PubMed publication ID30197595

P50authorKevin L SackQ87204473
Julius M. GuccioneQ108932948
P2093author name stringPartho P Sengupta
Yaghoub Dabiri
Semion Shaul
P2860cites workThe relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling studyQ26778602
Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometryQ27008247
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A computational model that predicts reverse growth in response to mechanical unloadingQ42262624
Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stressQ42426670
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Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling studyQ43195701
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Noninvasive single-beat determination of left ventricular end-systolic elastance in humansQ43818880
Organ-level validation of a cross-bridge cycling descriptor in a left ventricular finite element model: effects of ventricular loading on myocardial strainsQ44056670
The Many Dimensions of Diastolic Function: A Curse or a Blessing?Q45063941
Right ventricular strain in pulmonary hypertension: flavor du jour or enduring prognostic index?Q45152756
Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency.Q45921765
Geometry as a Confounder When Assessing Ventricular Systolic Function: Comparison Between Ejection Fraction and StrainQ47722084
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Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failureQ48883616
Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohortQ50648250
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Why Don't We Have Proven Treatments for HFpEF?Q51828593
Fiber shortening in the inner layers of the left ventricular wall as assessed from epicardial deformation during normoxia and ischemia.Q52698062
Two-dimensional echocardiographic assessment of left ventricular volumes and ejection fraction in children.Q52721514
Relation between left ventricular shape and exercise capacity in patients with left ventricular dysfunction.Q52885106
A novel mechanism of heart failure with normal ejection fraction.Q53571375
"Pure" diastolic dysfunction is associated with long-axis systolic dysfunction. Implications for the diagnosis and classification of heart failure.Q53621161
The relative role of subendocardium and subepicardium in left ventricular mechanicsQ70816191
Fiber Orientation in the Canine Left Ventricle during Diastole and SystoleQ72342396
Geometric changes allow normal ejection fraction despite depressed myocardial shortening in hypertensive left ventricular hypertrophyQ72351005
Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressuresQ73857203
Progression of systolic abnormalities in patients with "isolated" diastolic heart failure and diastolic dysfunctionQ77753952
Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricleQ80055213
Concentric left ventricular hypertrophy brings deterioration of systolic longitudinal, circumferential, and radial myocardial deformation in hypertensive patients with preserved left ventricular pump functionQ82736132
Heart failure with preserved ejection fraction: is it due to contractile dysfunction?Q83897232
Heart failure with preserved ejection fraction: invasive solution to diagnostic confusion?Q84068335
Phenotypic and pathophysiological heterogeneity in heart failure with preserved ejection fractionQ84451295
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
ejection fractionQ641303
P304page(s)1003
P577publication date2018-08-24
P1433published inFrontiers in PhysiologyQ2434141
P1476titleRelationship of Transmural Variations in Myofiber Contractility to Left Ventricular Ejection Fraction: Implications for Modeling Heart Failure Phenotype With Preserved Ejection Fraction
P478volume9

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cites work (P2860)
Q89736017Intramyocardial Injections to De-Stiffen the Heart: A Subject-Specific in Silico Approach
Q92425904Prediction of Left Ventricular Mechanics Using Machine Learning
Q92798053Tricuspid Valve Regurgitation Decreases after MitraClip Implantation: Fluid Structure Interaction Simulation

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