Lactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouse

scientific article published on 01 September 2018

Lactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.14814/PHY2.13800
P932PMC publication ID6144450
P698PubMed publication ID30230254

P50authorThomas Elbenhardt JensenQ47452518
Carlos Henríquez-OlguínQ51317527
Enrique JaimovichQ88337320
P2093author name stringMariana Casas
Paola Llanos
Hugo Cerda-Kohler
P2860cites workUnderstanding the effect size and its measuresQ26747077
Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exerciseQ28262423
Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81Q28302327
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1Q30854541
Lactate promotes plasticity gene expression by potentiating NMDA signaling in neuronsQ34041578
PDH-E1alpha dephosphorylation and activation in human skeletal muscle during exercise: effect of intralipid infusion.Q34576664
Lactate administration reproduces specific brain and liver exercise-related changesQ34770247
Distinct pathways of ERK1/2 activation by hydroxy-carboxylic acid receptor-1Q35132371
Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus)Q37091773
The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise.Q37160004
Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cellsQ37602202
AMPK-mediated regulation of transcription in skeletal muscle.Q37678570
Lactate kinetics in human tissues at rest and during exerciseQ37719602
Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implicationsQ38070636
The secretome of the working human skeletal muscle--a promising opportunity to combat the metabolic disaster?Q38174593
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chainQ38908127
Mixed lactate and caffeine compound increases satellite cell activity and anabolic signals for muscle hypertrophy.Q38922063
Lactate sensitive transcription factor network in L6 cells: activation of MCT1 and mitochondrial biogenesis.Q40152027
Effects of decreased lactate accumulation after dichloroacetate administration on exercise training-induced mitochondrial adaptations in mouse skeletal muscleQ40488675
Dehydration parameters and standards for laboratory miceQ42236780
Lactate regulates myogenesis in C2C12 myoblasts in vitro.Q42825883
Tubulin or Not Tubulin: Heading Toward Total Protein Staining as Loading Control in Western BlotsQ44425905
Glucose feeds the TCA cycle via circulating lactate.Q45952595
Skeletal muscle hypertrophy after chronic restriction of venous blood flow in ratsQ46598954
AMPK in skeletal muscle function and metabolism.Q47781006
Lactate metabolism: historical context, prior misinterpretations, and current understanding.Q48265527
A rapid, simple, and humane method for submandibular bleeding of mice using a lancetQ48773146
Muscles and their myokinesQ48943557
Lactate increases myotube diameter via activation of MEK/ERK pathway in C2C12 cells.Q49607850
5'-AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4.Q51596146
Lactate administration increases mRNA expression of PGC-1α and UCP3 in mouse skeletal muscle.Q53093361
Lactate and potassium fluxes from human skeletal muscle during and after intense, dynamic, knee extensor exercise.Q53837138
Lack of AMPKα2 enhances pyruvate dehydrogenase activity during exerciseQ64018947
Lactate alters plasma membrane potential, increases the concentration of cytosolic Ca2+ and stimulates the secretion of insulin by the hamster beta-cell line HIT-T15Q69534590
The Science and Translation of Lactate Shuttle TheoryQ88264743
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)e13800
P577publication date2018-09-01
P1433published inPhysiological ReportsQ15716763
P1476titleLactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouse
P478volume6

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cites work (P2860)
Q97568603Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
Q99608532Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise

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