Combination of EGFR Inhibitor Lapatinib and MET Inhibitor Foretinib Inhibits Migration of Triple Negative Breast Cancer Cell Lines

scientific article published on 17 September 2018

Combination of EGFR Inhibitor Lapatinib and MET Inhibitor Foretinib Inhibits Migration of Triple Negative Breast Cancer Cell Lines is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/CANCERS10090335
P932PMC publication ID6162814
P698PubMed publication ID30227653

P50authorAleksandra SimiczyjewQ59694016
Dorota NowakQ59694021
Ewelina DratkiewiczQ59696188
Marleen Van TroysQ61116293
Christophe AmpeQ87750495
P2093author name stringIlona Styczeń
P2860cites workNIH Image to ImageJ: 25 years of image analysisQ23319322
EGFR/Met association regulates EGFR TKI resistance in breast cancerQ24338635
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biologyQ26849519
Analysis of Invasion Dynamics of Matrix-Embedded Cells in a Multisample Format.Q52360252
Epidermal growth factor receptor expression as a prognostic indicator in breast cancerQ67902986
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signalingQ27851406
Met, metastasis, motility and moreQ28235183
Assembly and biological role of podosomes and invadopodiaQ28272503
Triple-Negative Breast CancerQ29391607
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitorsQ29547463
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapiesQ29615606
CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assaysQ30659486
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.Q34032640
Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancerQ34135362
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.Q34307548
cMET Activation and EGFR-Directed Therapy Resistance in Triple-Negative Breast CancerQ34438708
Drug development of MET inhibitors: targeting oncogene addiction and expedienceQ34782774
Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6Q35625440
MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibitionQ36265149
Signaling networks assembled by oncogenic EGFR and c-MetQ36392991
Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cellsQ37141943
cMET and phospho-cMET protein levels in breast cancers and survival outcomesQ37290053
Cell migration and invasion assays as tools for drug discoveryQ37378102
Crosstalk in Met receptor oncogenesisQ37598460
Understanding breast cancer - The long and winding roadQ37634220
Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers.Q37688459
Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?Q37694203
MET is a potential target for use in combination therapy with EGFR inhibition in triple-negative/basal-like breast cancer.Q39016645
The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrixQ39350905
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and functionQ40304153
Mechanism of action of the multikinase inhibitor Foretinib.Q44633972
Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: prognostic implications of EGFR immunoreactivityQ46328432
EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutationsQ46513909
Active invadopodia of mesenchymally migrating cancer cells contain both β and γ cytoplasmic actin isoformsQ49099425
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
cancer researchQ3421914
P304page(s)335
P577publication date2018-09-17
P1433published inCancersQ27722963
P1476titleCombination of EGFR Inhibitor Lapatinib and MET Inhibitor Foretinib Inhibits Migration of Triple Negative Breast Cancer Cell Lines
P478volume10

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cites work (P2860)
Q64926935Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer.
Q92935028Targeting Tyrosine Kinases in Cancer: Lessons for an Effective Targeted Therapy in the Clinic

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