Physiological and pathological osteocytic osteolysis

Physiological and pathological osteocytic osteolysis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P932PMC publication ID6146198
P698PubMed publication ID30179206

P2093author name stringMartina Rauner
Lynda F Bonewald
Katharina Jähn
Elena Tsourdi
Björn Busse
P2860cites workInfluence of lactation and pregnancy + lactation on mechanical properties and mineral content of the rat femurQ68717334
Dynamics of changes of calcium and phosphorus metabolism in relation to the morphology of parafollicular thyroid cells in rats during lactation and forced weaningQ68928305
The mRNA encoding a parathyroid hormone-like peptide is produced in mammary tissue in response to elevations in serum prolactinQ69419616
Reproductive history and postmenopausal risk of hip and forearm fractureQ69561679
Elevated serum parathyroid hormone, calcitonin, and 1,25-dihydroxyvitamin D in lactating women nursing twinsQ70815421
Periosteocyte demineralization in disuse osteoporsis. The effect of calcitoninQ71106677
Changes in bone mineral density and markers of bone remodeling during lactation and postweaning in women consuming high amounts of calciumQ71595571
Sensitivity of osteocytes to biomechanical stress in vitroQ72643863
The cellular basis of metastatic bone disease in patients with lung cancerQ72914415
Development of bone canaliculi during bone repairQ73150120
Effects of pregnancy and lactation on trabecular bone and marrow adipocytes in ratsQ73341635
The death of osteocytes via apoptosis accompanies estrogen withdrawal in human boneQ73668383
Calcitonin inhibition of prolactin secretion in lactating rats: mechanism of actionQ73907725
Influence of number of pregnancies and total breast-feeding time on bone mineral densityQ74672745
Enlargement of periosteocytic lacunae associated to mechanical forcesQ77746046
Weaning triggers a decrease in receptor activator of nuclear factor-kappaB ligand expression, widespread osteoclast apoptosis, and rapid recovery of bone mass after lactation in miceQ80313586
Effects of pregnancy and lactation on bone mineral density, and their relation to the serum calcium, phosphorus, calcitonin and parathyroid hormone levels in ratsQ81869567
Vitamin D regulates osteocyte survival and perilacunar remodeling in human and murine boneQ88427613
Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactationQ24645591
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonistQ24646652
Control of bone mass and remodeling by PTH receptor signaling in osteocytesQ27300741
Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosisQ27324822
Evidence for osteocyte regulation of bone homeostasis through RANKL expressionQ28247757
Quantifying the osteocyte network in the human skeletonQ28257645
Reproductive, menstrual and menopausal factors: which are associated with bone mineral density in early postmenopausal women?Q31018328
Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathwayQ31032805
Osteocyte ultrastructure in renal osteodystrophyQ33191294
Osteocyte apoptosis and control of bone resorption following ovariectomy in miceQ33665257
Increased PTHrP and Decreased Estrogens Alter Bone Turnover but Do Not Reproduce the Full Effects of Lactation on the SkeletonQ34392597
Cancellous bone structure of iliac crest biopsies following 370 days of head-down bed rest.Q34461052
Microgravity induces pelvic bone loss through osteoclastic activity, osteocytic osteolysis, and osteoblastic cell cycle inhibition by CDKN1a/p21.Q34700233
The first 50 years of total hip arthroplasty: lessons learnedQ34872021
Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysisQ35143361
Ovariectomy enhances mechanical load-induced solute transport around osteocytes in rat cancellous boneQ35174737
Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient miceQ35634073
Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engenderedQ35831180
An electron microscopic investigation of human familial bone dysplasia. Inhibition of osteocytic osteolysis and induction of osteocytic formation of elastic fibers following calcitonin treatmentQ36092689
Light- and electron-microscopic evaluation of the effects of 1,25-dihydroxyvitamin D3 on bone of thyroparathyroidectomized ratsQ36093281
Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistanceQ36153043
Osteocyte RANKL: new insights into the control of bone remodelingQ36253514
Osteoporosis after spinal cord injuryQ36283120
Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageingQ36298761
Osteocyte Remodeling of the Perilacunar and Pericanalicular MatrixQ36313876
Bone changes in hemodialyzed uremic subjects. Comparative light and electron microscope investigationsQ36755317
Osteocytes remove and replace perilacunar mineral during reproductive cyclesQ36759496
Lactating Ctcgrp nulls lose twice the normal bone mineral content due to fewer osteoblasts and more osteoclasts, whereas bone mass is fully restored after weaning in association with up-regulation of Wnt signaling and other novel genesQ36917546
Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation.Q37163219
Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responsesQ37199498
The osteocyte: an endocrine cell ... and moreQ37203605
Immunolocalization of MMP 2, 9 and 13 in prednisolone induced osteoporosis in mice.Q50546172
Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis.Q50926801
Human lactation: forearm trabecular bone loss, increased bone turnover, and renal conservation of calcium and inorganic phosphate with recovery of bone mass following weaning.Q51616238
Calcium metabolism during lactation: elevated blood levels of calcitoninQ51664421
An interpretation of acute changes in plasma 45Ca following parathyroid hormone administration to thyroparathyroidectomized rats.Q51669094
Osteocyte density in woven bone.Q52085750
Evidence that osteocyte perilacunar remodelling contributes to polyethylene wear particle induced osteolysis.Q53203543
Intravital bone imaging by two-photon excitation microscopy to identify osteocytic osteolysis in vivo.Q53634752
Pattern of Bone Markers during Pregnancy and Their Changes after DeliveryQ57818868
The Role of Estrogen in the Control of Rat Osteocyte ApoptosisQ59755571
Modifications to Nano- and Microstructural Quality and the Effects on Mechanical Integrity in Paget's Disease of BoneQ60465135
Changes in Cortical Volumetric Bone Mineral Density and Thickness, and Trabecular Thickness in Lactating Women PostpartumQ61480234
Bone histomorphometry in Paget's disease. Quantitative and dynamic analysis of pagetic and nonpagetic bone tissue.Q64989586
Effect of PTH on osteocyte ultrastructureQ67413535
Calcium deficiency, pregnancy, and lactation in rats. Microscopic and microradiographic observations on bonesQ67652438
Effect of number of suckling pups and dietary calcium on bone mineral content and mechanical properties of femurs of lactating ratsQ68036792
The ovariectomized, lactating rat as an experimental model for osteopenia: calcium metabolism and bone changesQ68645214
Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited.Q37314649
Minireview: live and let die: molecular effects of glucocorticoids on bone cells.Q37499649
Vitamin D endocrine system and osteocytesQ37620408
Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosisQ37714895
Osteocyte regulation of bone mineral: a little give and take.Q37981072
Presentation and management of osteoporosis presenting in association with pregnancy or lactationQ38457933
Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning RecoveryQ38737740
The Skeleton Is a Storehouse of Mineral That Is Plundered During Lactation and (Fully?) Replenished AfterwardsQ38972532
Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.Q39143854
Lactation-Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue.Q39177340
Matrix Metalloproteinases in Bone Resorption, Remodeling, and Repair.Q39405393
Changes to the cell, tissue and architecture levels in cranial suture synostosis reveal a problem of timing in bone development.Q39512745
A physiological role for calcitonin: protection of the maternal skeletonQ39568647
Immobilization and long-term recovery results in large changes in bone structure and strength but no corresponding alterations of osteocyte lacunar properties.Q39610142
Site-specific changes in bone microarchitecture, mineralization, and stiffness during lactation and after weaning in miceQ39673212
Osteocyte lacunae tissue strain in cortical boneQ39722219
Co-Cr-Mo alloy particles induce tumor necrosis factor alpha production in MLO-Y4 osteocytes: a role for osteocytes in particle-induced inflammationQ39842640
The induction of a catabolic phenotype in human primary osteoblasts and osteocytes by polyethylene particlesQ39863734
Osteocytic osteolysisQ39891592
Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratioQ40029157
Osteocyte-directed bone demineralization along canaliculiQ40166530
An investigation of skeletal indicators of vitamin D deficiency in adults: effective markers for interpreting past living conditions and pollution levels in 18th and 19th century Birmingham, EnglandQ40273748
Calcitonin inhibits prolactin promoter activity in rat pituitary GGH3 cells: evidence for involvement of p42/44 mitogen-activated protein kinase in calcitonin actionQ40659607
A Role for the Calcitonin Receptor to Limit Bone Loss During Lactation in Female Mice by Inhibiting Osteocytic Osteolysis.Q40775024
Osteocytes, strain detection, bone modeling and remodelingQ40797954
Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactationQ41668487
Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(-/-) mice.Q42272777
Inhibitory effects of β-tricalciumphosphate wear particles on osteocytes via apoptotic response and Akt inactivationQ42718686
Bone modeling in bromocriptine-treated pregnant and lactating rats: possible osteoregulatory role of prolactin in lactationQ43020607
A tetracycline-based histomorphometric evaluation of bone resorption and bone turnover in hyperthyroidism and hyperparathyroidismQ43418128
The measurement of periosteocytic enlargement in primary and secondary hyperparathyroidismQ43458906
Low Estrogen and High Parathyroid Hormone-Related Peptide Levels Contribute to Accelerated Bone Resorption and Bone Loss in Lactating MiceQ44590717
Vitamin D deficiency induces early signs of aging in human bone, increasing the risk of fractureQ44987398
Osteocytic osteolysis observed in rats to which parathyroid hormone was continuously administeredQ45111399
The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption--bone flow theoryQ45398311
Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling.Q45978159
Ultrastructural changes in osteocytes in microgravity conditionsQ46287559
Maternal and weanling bone: the influence of lowered calcium intake and maternal dietary historyQ46295573
Arctic Ground Squirrels Limit Bone Loss during the Prolonged Physical Inactivity Associated with HibernationQ46563112
Recombinant sclerostin antagonises effects of ex vivo mechanical loading in trabecular bone and increases osteocyte lacunar sizeQ47183965
Hormonal Regulation of Osteocyte Perilacunar and Canalicular Remodeling in the Hyp Mouse Model of X-Linked HypophosphatemiaQ47589028
Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo.Q50202540
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 3.0 UnportedQ15643954
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcalciumQ706
inorganic compoundQ190065
osteocyteQ913236
osteolysisQ2035084
cellQ7868
P304page(s)292-303
P577publication date2018-09-01
P1433published inThe Journal of Musculoskeletal and Neuronal InteractionsQ15762443
P1476titlePhysiological and pathological osteocytic osteolysis
P478volume18

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cites work (P2860)
Q64885250Bone matrix mineralization and osteocyte lacunae characteristics in patients with chronic kidney disease - mineral bone disorder (CKD-MBD).
Q64242881Etiology and Measurement of Peri-Implant Crestal Bone Loss (CBL)
Q92407825On the Origins of Fracture Toughness in Advanced Teleosts: How the Swordfish Sword's Bone Structure and Composition Allow for Slashing under Water to Kill or Stun Prey
Q92718272Physicochemical Niche Conditions and Mechanosensing by Osteocytes and Myocytes
Q64065836Protective Effects of Fermented Oyster Extract against RANKL-Induced Osteoclastogenesis through Scavenging ROS Generation in RAW 264.7 Cells
Q98177574The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases
Q92060722Towards a Connectomic Description of the Osteocyte Lacunocanalicular Network in Bone

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