Chemical genetic inhibition of DEAD-box proteins using covalent complementarity

Chemical genetic inhibition of DEAD-box proteins using covalent complementarity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKY706
P932PMC publication ID6158709
P698PubMed publication ID30102385

P2093author name stringKevan M Shokat
Qi Hu
Megan K Moore
Krister J Barkovich
P2860cites workStructure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine KinasesQ56552583
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ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwindingQ24646651
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Fal1p is an essential DEAD-box protein involved in 40S-ribosomal-subunit biogenesis in Saccharomyces cerevisiaeQ27931519
Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA exportQ27934203
Requirement of the DEAD-Box protein ded1p for messenger RNA translationQ27935125
The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complexQ27936899
The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae.Q27937737
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA exportQ27937989
Dynamics and processivity of 40S ribosome scanning on mRNA in yeastQ27938279
Has1 regulates consecutive maturation and processing steps for assembly of 60S ribosomal subunitsQ27938446
A suppressor of yeastspp81/ded1mutations encodes a very similar putative ATP-dependent RNA helicaseQ27939425
Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicingQ27939473
Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell deathQ28295447
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathwaysQ28306744
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The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysisQ33963813
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Functional interrogation of the kinome using nucleotide acyl phosphatesQ34599227
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A cellular response linking eIF4AI activity to eIF4AII transcription.Q36060820
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.Q36518348
Remodeling of ribonucleoprotein complexes with DExH/D RNA helicasesQ36578952
Analog sensitive chemical inhibition of the DEAD-box protein DDX3Q36749699
DEAD-box proteins can completely separate an RNA duplex using a single ATP.Q37068571
Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAsQ37104721
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice SitesQ37165431
Aryloxy phosphoramidate triesters: a technology for delivering monophosphorylated nucleosides and sugars into cellsQ37598750
From unwinding to clamping - the DEAD box RNA helicase familyQ37903659
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)8689-8699
P577publication date2018-09-28
P1433published inNucleic Acids ResearchQ135122
P1476titleChemical genetic inhibition of DEAD-box proteins using covalent complementarity
P478volume46

Reverse relations

Q91841007The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3Xcites workP2860

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