| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/1529-0131(199802)41:2<284::AID-ART12>3.0.CO;2-T |
| P698 | PubMed publication ID | 9485086 |
| P2093 | author name string | Blanco FJ | |
| Galdo F | |||
| Fausto Galdo | |||
| Francisco J. Blanco | |||
| de Toro FJ | |||
| Guitian R | |||
| Eduardo V�zquez-Martul | |||
| Francisco J. de Toro | |||
| Ram�n Guitian | |||
| Vázquez-Martul E | |||
| P2860 | cites work | Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death | Q24312211 |
| P433 | issue | 2 | |
| P921 | main subject | apoptotic process | Q14599311 |
| pathology | Q7208 | ||
| rheumatology | Q327657 | ||
| osteoarthritis | Q62736 | ||
| immunology | Q101929 | ||
| P304 | page(s) | 284-289 | |
| P577 | publication date | 1998-02-01 | |
| P1433 | published in | Arthritis and Rheumatism | Q23929027 |
| P1476 | title | Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology | |
| Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology | |||
| P478 | volume | 41 |
| Q36159219 | 17β-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl(-) current in rabbit articular chondrocytes |
| Q41395349 | 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase |
| Q35718396 | 75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes |
| Q35028071 | A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis |
| Q58629385 | A hypothesis for the origin and pathogenesis of rheumatoid diseases |
| Q41785351 | Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee |
| Q100490847 | Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death |
| Q35649296 | Age-dependent alteration of TGF-β signalling in osteoarthritis |
| Q37136657 | Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification |
| Q34034399 | Aging and the etiopathogenesis and treatment of osteoarthritis |
| Q41177487 | Ammonium-Chloride-Potassium Lysing Buffer Treatment of Fully Differentiated Cells Increases Cell Purity and Resulting Neotissue Functional Properties |
| Q48241023 | An ultrastructural study of chondroptosis: programmed cell death in degenerative intervertebral discs in vivo. |
| Q37450277 | Anti-apoptotic treatments prevent cartilage degradation after acute trauma to human ankle cartilage |
| Q35193756 | Apoptosis and the loss of chondrocyte survival signals contribute to articular cartilage degradation in osteoarthritis |
| Q35549052 | Apoptosis in normal and osteoarthritic human articular cartilage |
| Q34074029 | Apoptosis in rheumatic diseases |
| Q53480157 | Apoptosis in the traumatic and degenerative tears of human meniscus. |
| Q86081826 | Apoptosis-related Fas and FasL gene polymorphisms' associations with knee osteoarthritis |
| Q37957102 | Arthroscopic optical coherence tomography in diagnosis of early arthritis |
| Q24805351 | Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis |
| Q34637361 | Articular cartilage calcification and matrix vesicles |
| Q44466389 | Articular chondrocyte apoptosis in equine osteoarthritis |
| Q42286696 | Assessment of apoptosis and MMP-1, MMP-3 and TIMP-2 expression in tibial hyaline cartilage after viable medial meniscus transplantation in the rabbit |
| Q64100869 | Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis |
| Q41836157 | Biological Effects of Phosphocitrate on Osteoarthritic Articular Chondrocytes |
| Q41810542 | Biological activities of phosphocitrate: a potential meniscal protective agent |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q35115937 | Biomineralization and matrix vesicles in biology and pathology |
| Q42566865 | Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes |
| Q42420906 | CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase |
| Q37761086 | Cartilage cell clusters. |
| Q28067045 | Cell Death in Chondrocytes, Osteoblasts, and Osteocytes |
| Q44550345 | Cell death after cartilage impact occurs around matrix cracks |
| Q24296780 | Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model |
| Q39561182 | Cellular and molecular mechanisms of anti-inflammatory effect of Aflapin: a novel Boswellia serrata extract. |
| Q34375821 | Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes. |
| Q42131847 | Chondrocyte apoptosis after simulated intraarticular fracture: a comparison of histologic detection methods |
| Q44680714 | Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase inhibitors and IGF-1. |
| Q58629512 | Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis |
| Q36975916 | Chondrocyte apoptosis: implications for osteochondral allograft transplantation |
| Q33182361 | Chondrocyte necrosis and apoptosis in impact damaged articular cartilage |
| Q35553649 | Chondrocyte number and proteoglycan synthesis in the aging and osteoarthritic human articular cartilage |
| Q36761822 | Chopping off the chondrocyte proteome |
| Q92055277 | Cladophora glomerata methanolic extract promotes chondrogenic gene expression and cartilage phenotype differentiation in equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome |
| Q88325112 | Comparative evaluation of therapeutic efficacy of intra-articular oxaceprol with conventional modalities in osteoarthritis animal model |
| Q47766205 | Comparison of Intra-articular Injection of Hyaluronic Acid and N-Acetyl Cysteine in the Treatment of Knee Osteoarthritis: A Pilot Study |
| Q36392260 | Comparison of marker gene expression in chondrocytes from patients receiving autologous chondrocyte transplantation versus osteoarthritis patients |
| Q43716640 | Corticosteroids alter the differentiated phenotype of articular chondrocytes |
| Q41947962 | Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro |
| Q92815441 | Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy |
| Q21195655 | Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation |
| Q35556209 | Detecting cathepsin activity in human osteoarthritis via activity-based probes. |
| Q38802370 | Developmental mechanisms in articular cartilage degradation in osteoarthritis |
| Q36999290 | Differences in Mammalian target of rapamycin gene expression in the peripheral blood and articular cartilages of osteoarthritic patients and disease activity |
| Q99725049 | Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy |
| Q46271260 | Distribution of chondroitin 4-sulfate epitopes (2/B/6) in various zones and compartments of articular cartilage in guinea pig osteoarthrosis |
| Q36781506 | Down-regulation of programmed cell death 5 by insulin-like growth factor 1 in osteoarthritis chondrocytes |
| Q92738289 | Effect of chondrocyte mitochondrial dysfunction on cartilage degeneration: A possible pathway for osteoarthritis pathology at the subcellular level |
| Q39675358 | Effect of hyaluronic acid on chondrocyte apoptosis |
| Q43049067 | Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocytes. |
| Q83425376 | Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit |
| Q38032567 | Effects of diacerein at the molecular level in the osteoarthritis disease process |
| Q46500387 | Effects of different hyaluronic acid products on synovial fluid NO levels in knee osteoarthritis |
| Q37661071 | Effects of flurbiprofen and tiaprofenic Acid on oxidative stress markers in osteoarthritis: A prospective, randomized, open-label, active- and placebo-controlled trial |
| Q79443313 | Effects of hyaluronan on nitric oxide levels and superoxide dismutase activities in synovial fluid in knee osteoarthritis |
| Q34108064 | Emerging roles of SUMO modification in arthritis |
| Q54615289 | Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage. |
| Q43292144 | Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography |
| Q24670233 | Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes |
| Q49629822 | Expression of miR-625 and Fas in cervical vertebral cartilage endplate |
| Q21284705 | Glucosamine for osteoarthritis: biological effects, clinical efficacy, and safety on glucose metabolism |
| Q28538884 | High resolution T1ρ mapping of in vivo human knee cartilage at 7T |
| Q42728804 | Hyaluronic acid in the treatment of osteoarthritis |
| Q43193622 | Hyaluronic acid inhibits nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes in vitro |
| Q35754688 | Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction |
| Q43772901 | In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1beta synthesis |
| Q43049177 | Increased Bcl-2/p53 ratio in human osteoarthritic cartilage: a possible role in regulation of chondrocyte metabolism |
| Q36390894 | Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. |
| Q42663802 | Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease. |
| Q34164358 | Increased chondrocyte death after steroid and local anesthetic combination. |
| Q37294661 | Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint? |
| Q33194160 | Induction of Chondrocyte Apoptosis Following Impact Load |
| Q40459944 | Inhibition of NF-kappaB renders human juvenile costal chondrocyte cell lines sensitive to TNF-alpha-mediated cell death. |
| Q44586253 | Inhibition of chondrocyte apoptosis in vivo following acute osteochondral injury |
| Q34673887 | Initial responses of articular tissues in a murine high-fat diet-induced osteoarthritis model: pivotal role of the IPFP as a cytokine fountain |
| Q28079781 | Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis |
| Q36632678 | Intra-articular injection of collagenase induced experimental osteoarthritis of the lumbar facet joint in rats |
| Q34052510 | Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence |
| Q90042061 | Ipomoea batatas L. Lam. ameliorates acute and chronic inflammations by suppressing inflammatory mediators, a comprehensive exploration using in vitro and in vivo models |
| Q41877821 | Joint aging and chondrocyte cell death |
| Q89731175 | LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes |
| Q64262276 | LncRNA CASC2 is up-regulated in osteoarthritis and participates in the regulation of IL-17 expression and chondrocyte proliferation and apoptosis |
| Q47144390 | Long noncoding RNAs: a new regulatory code in osteoarthritis |
| Q36903237 | MMP13 is a critical target gene during the progression of osteoarthritis. |
| Q92309799 | Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis |
| Q43603732 | Matrix and cell injury due to sub-impact loading of adult bovine articular cartilage explants: effects of strain rate and peak stress |
| Q41900177 | Matrix metalloproteinase-3 inhibitor retards treadmill running-induced cartilage degradation in rats |
| Q41578159 | Mechanical impact induces cartilage degradation via mitogen activated protein kinases. |
| Q80543447 | Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence |
| Q36375160 | Mefloquine inhibits chondrocytic proliferation by arresting cell cycle in G2/M phase |
| Q91598712 | Menisci protect chondrocytes from load-induced injury |
| Q46588283 | Metabolic regulatory and anti-oxidative effects of modified Bushen Huoxue decoction on experimental rabbit model of osteoarthritis |
| Q98464903 | Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model |
| Q53530608 | MiR-34a promotes Fas-mediated cartilage endplate chondrocyte apoptosis by targeting Bcl-2. |
| Q48146266 | MicroRNA-142-3p Inhibits Chondrocyte Apoptosis and Inflammation in Osteoarthritis by Targeting HMGB1. |
| Q36983759 | MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis |
| Q37358880 | MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin |
| Q40967339 | Microarray study of gene expression profile to identify new candidate genes involved in the molecular mechanism of leptin-induced knee joint osteoarthritis in rat |
| Q44359278 | Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes |
| Q36832831 | Modulation of Apoptosis and Differentiation by the Treatment of Sulfasalazine in Rabbit Articular Chondrocytes |
| Q35405312 | Myrtol ameliorates cartilage lesions in an osteoarthritis rat model |
| Q91994891 | NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction |
| Q34108748 | New developments in the pathogenesis of articular cartilage calcification |
| Q36249227 | Nitric oxide-associated chondrocyte apoptosis in trauma patients after high-energy lower extremity intra-articular fractures |
| Q44317021 | Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity |
| Q37071636 | Optimized extraction of glycosaminoglycans from normal and osteoarthritic cartilage for glycomics profiling |
| Q30384235 | Oral Resveratrol Prevents Osteoarthritis Progression in C57BL/6J Mice Fed a High-Fat Diet |
| Q35629588 | Osteoarthritis gene therapy |
| Q64115712 | Osteochondritis Dissecans (OCD)-Derived Chondrocytes Display Increased Senescence, Oxidative Stress, Chaperone-Mediated Autophagy and, in Co-Culture with Adipose-Derived Stem Cells (ASCs), Enhanced Expression of MMP-13 |
| Q36955737 | Oxidative DNA damage in osteoarthritic porcine articular cartilage |
| Q35128894 | Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation? |
| Q93102832 | PKR Promotes Oxidative Stress and Apoptosis of Human Articular Chondrocytes by Causing Mitochondrial Dysfunction through p38 MAPK Activation-PKR Activation Causes Apoptosis in Human Chondrocytes |
| Q46594882 | Pathogenesis of osteoarthritis: chondrocyte replicative senescence or apoptosis? |
| Q89920243 | Pathomechanisms of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment |
| Q37406721 | Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes |
| Q36128347 | Pleiotropic Functions of High Fat Diet in the Etiology of Osteoarthritis |
| Q37721704 | Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint |
| Q34978123 | Posttraumatic Chondrocyte Apoptosis in the Murine Xiphoid |
| Q86069230 | Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study |
| Q33651413 | Potential treatment of osteoarthritis by gene therapy |
| Q36709565 | Preventing friction-induced chondrocyte apoptosis: comparison of human synovial fluid and hylan G-F 20 |
| Q28729755 | Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model |
| Q42922750 | Prologation of c-Jun N-terminal kinase is associated with cell death induced by tumor necrosis factor alpha in human chondrocytes |
| Q42120262 | Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13. |
| Q34896802 | Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis |
| Q73389427 | Proteoglycan metabolism and viability of articular cartilage explants as modulated by the frequency of intermittent loading |
| Q44474732 | Quantitative assessment of articular cartilage and subchondral bone histology in the meniscectomized guinea pig model of osteoarthritis |
| Q43683241 | Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes |
| Q33467734 | Regulatory role of tyrosine phosphorylation in the swelling-activated chloride current in isolated rabbit articular chondrocytes |
| Q34996594 | Response of engineered cartilage to mechanical insult depends on construct maturity |
| Q36762604 | Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis |
| Q44623692 | Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis |
| Q38836896 | Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis |
| Q34347383 | Saponin-rich fraction from Clematis chinensis Osbeck roots protects rabbit chondrocytes against nitric oxide-induced apoptosis via preventing mitochondria impairment and caspase-3 activation |
| Q34286902 | Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte. |
| Q59393051 | Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies |
| Q84627089 | Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro |
| Q34072652 | SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. |
| Q28211978 | Site-specific analysis of gene expression in early osteoarthritis using the Pond-Nuki model in dogs |
| Q41863154 | Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1α in primary cultured rat chondrocytes |
| Q37728295 | Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model |
| Q58699693 | TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation |
| Q44071629 | TNF-alpha-mediated apoptosis in chondrocytes sensitized by MG132 or actinomycin D. |
| Q54597646 | TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor. |
| Q42916722 | The COX-2 selective blocker etodolac inhibits TNFα-induced apoptosis in isolated rabbit articular chondrocytes |
| Q33781278 | The effect of low-level laser to apoptosis of chondrocyte and caspases expression, including caspase-8 and caspase-3 in rabbit surgery-induced model of knee osteoarthritis |
| Q53199147 | The effect of therapeutic ultrasound to apoptosis of chondrocyte and caspase-3 and caspase-8 expression in rabbit surgery-induced model of knee osteoarthritis. |
| Q90057626 | The evaluation of oxidative stress in osteoarthritis |
| Q37423992 | The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity |
| Q43741095 | The extent of matrix damage and chondrocyte death in mechanically traumatized articular cartilage explants depends on rate of loading |
| Q24816697 | The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death |
| Q42914772 | The properties of chondrocyte membrane reservoirs and their role in impact-induced cell death. |
| Q42067688 | The role of different hyaluronic acids in the articular cartilage of rabbit |
| Q37825773 | The role of mitochondria in osteoarthritis |
| Q34537354 | The role of reactive oxygen species in homeostasis and degradation of cartilage |
| Q51088098 | Therapeutic ultrasound effects on interleukin-1beta stimulated cartilage construct in vitro. |
| Q73811973 | Time, stress, and location dependent chondrocyte death and collagen damage in cyclically loaded articular cartilage |
| Q43078215 | Transcriptional activity of the RHOB gene is influenced by regulatory polymorphisms in its promoter region |
| Q52539927 | Tumor necrosis factor-alpha induced DNA cleavage in human articular chondrocytes may involve multiple endonucleolytic activities during apoptosis. |
| Q43103880 | Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage |
| Q81579454 | [Pathogenesis of osteoarthritis--a snapshot] |
| Q39012355 | lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis |
| Q87903836 | miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis |
| Q36245802 | miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4. |
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