NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

scientific article published in Nature

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1015629795
P356DOI10.1038/321519A0
P698PubMed publication ID3012362

P2093author name stringBarker JL
Smith SJ
MacDermott AB
Mayer ML
Westbrook GL
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Glutamate stimulates inositol phosphate formation in striatal neuronesQ28282165
Magnesium gates glutamate-activated channels in mouse central neuronesQ29616237
Inositol trisphosphate, a novel second messenger in cellular signal transductionQ29618048
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neuronesQ34255679
The permeability of endplate channels to monovalent and divalent metal cationsQ36408134
Calcium-induced release of calcium from the sarcoplasmic reticulum of skinned cells from adult human, dog, cat, rabbit, rat, and frog hearts and from fetal and new-born rat ventriclesQ39776061
Excitatory Amino Acid TransmittersQ40084320
Receptors for the excitatory amino acids in the mammalian central nervous systemQ40093277
Calcium ChannelQ40124349
The selectivity of ion channels in nerve and muscleQ40131210
N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cellsQ47955283
Stimulus- and amino acid-induced calcium and potassium changes in rat neocortexQ48585664
Mg2+ dependence of membrane resistance increases evoked by NMDA in hippocampal neurones.Q48613834
Intracellular injections of EGTA block induction of hippocampal long-term potentiationQ48724517
Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampusQ48846262
Aspartate and glutamate induced reductions in extracellular free calcium and sodium concentration in area CA1 of 'in vitro' hippocampal slices of rats.Q51856176
The action of N-methyl-D-aspartic acid on mouse spinal neurones in culture.Q54452906
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clampQ54469825
Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparationsQ54547724
New class of glutamate agonist structurally related to ibotenic acidQ55062248
Intracellular calcium accumulation during depolarization in a molluscan neuroneQ70767677
The ionic mechanism of the excitatory action of glutamate upon the membranes of motoneurones of the frogQ70984492
Detection of intracellular Ca2+ transients in sympathetic neurones using arsenazo IIIQ71804320
3HNoradrenaline Release from Brain Slices Induced by an Increase in the Intracellular Sodium Concentration: Role of Intracellular Calcium StoresQ72690116
P433issue6069
P407language of work or nameEnglishQ1860
P921main subjectcalciumQ706
P304page(s)519-522
P577publication date1986-05-01
P1433published inNatureQ180445
P1476titleNMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
P478volume321

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Q42504860Immunocytochemical localization of calcineurin in the adult and developing primary visual cortex of cats
Q48378649Immunocytochemical localization of the NMDA-R2A receptor subunit in the cat retina
Q39990014Immunolocalization of NMDA receptor subunit NR3B in selected structures in the rat forebrain, cerebellum, and lumbar spinal cord
Q28140990Immunolocalization of mGluR1alpha in specific populations of local circuit neurons in the cerebral cortex
Q28507147Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice
Q53816745In CA1 pyramidal neurons of the hippocampus protein kinase C regulates calcium-dependent inactivation of NMDA receptors.
Q40942034In Vitro Differentiation of Human Neural Progenitor Cells Into Striatal GABAergic Neurons.
Q52206808In situ hybridization analysis of AMPA receptor subunit gene expression in the developing rat spinal cord
Q93925955In vitro neuroprotection against glutamate toxicity provided by novel non-competitive N-methyl-D-aspartate antagonists
Q42518565In vivo Fluorometric Measurement of Changes in Cytosolic Free Calcium from the Cat Cortex during Anoxia
Q48229909In vivo glutamate neurotoxicity is associated with reductions in calcium/calmodulin-dependent protein kinase II immunoreactivity
Q28278075Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit
Q90308827Inducible rodent models of glaucoma
Q57767762Induction of homosynaptic long-term depression at spinal synapses of sensory Aδ-fibers requires activation of metabotropic glutamate receptors
Q37280686Inhaled nitric oxide and neuroprotection in preterm infants
Q67656721Inhibition of Muscarinic-Coupled Phosphoinositide Hydrolysis by N-Methyl-d-Aspartate Is Dependent on Depolarization via Channel Activation
Q42847446Inhibition of N-methyl-D-aspartate- and kainic acid-induced neurotransmitter release by omega-conotoxin GVIA.
Q64910729Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons.
Q30304257Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics
Q43824558Inhibitory effects of excitatory amino acids on pyramidal cells of the in vitro turtle medial cortex
Q46759655Insensitivity to glutamate neurotoxicity mediated by NMDA receptors in association with delayed mitochondrial membrane potential disruption in cultured rat cortical neurons.
Q41126276Insulinoma Causing Prolonged Hypoglycaemic Coma
Q60177449Interaction between Calcium Channel Blockers and Sweetening Agents on Morphine-Induced Analgesia in Mice by Formalin Test
Q60177450Interaction between Lead Acetate and Morphine on Antinociception in Mice by Formalin Test
Q48391767Interactions between excitatory amino acids and tachykinins in the rat spinal dorsal horn
Q35947358Interactions between two divalent ion binding sites in N-methyl-D-aspartate receptor channels
Q41153034Interactions of recurrent inhibitory and muscle spindle afferent feedback during muscle fatigue
Q43581713Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity.
Q29618946Interneurons of the hippocampus
Q36410519Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo
Q48291505Intracellular calcium and magnesium: critical determinants of excitotoxicity?
Q69377783Intracellular calcium mobilization triggered by a glutamate receptor in rat cultured hippocampal cells
Q41711801Intracellular signalling mediating HIV-1 gp120 neurotoxicity.
Q38940235Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration.
Q73208151Involvement of cGMP in nociceptive processing by and sensitization of spinothalamic neurons in primates
Q42161881Involvement of the C-terminus of the inositol 1,4,5-trisphosphate receptor in Ca2+ release analysed using region-specific monoclonal antibodies
Q48442632Ion homeostasis in rat brain in vivo: intra- and extracellular [Ca2+] and [H+] in the hippocampus during recovery from short-term, transient ischemia
Q68318791Ionic and synaptic mechanisms underlying a brainstem oscillator: An in vitro study of the pacemaker nucleus of Apteronotus
Q54135551Ionic mechanisms implicated in the stimulation of cerebellar cyclic GMP levels by N-methyl-D-aspartate.
Q36411434Ionic permeability characteristics of the N-methyl-D-aspartate receptor channel
Q40883489Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators
Q37143580Ionotropic glutamate receptors & CNS disorders.
Q26823531Ionotropic glutamate receptors and voltage-gated Ca²⁺ channels in long-term potentiation of spinal dorsal horn synapses and pain hypersensitivity
Q38201322Is contiguity detection in classical conditioning a system or a cellular property? Learning in Aplysia suggests a possible molecular site
Q35644646Ischemia induces short- and long-term remodeling of synaptic activity in the hippocampus.
Q41283801Ischemia-induced changes in the electrical activity of the hippocampus.
Q57982911Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3
Q91810081Isoform-specific Inhibition of N-methyl-D-aspartate Receptors by Bile Salts
Q92509567KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion
Q37045937Kainate-induced calcium overload of cortical neurons in vitro: Dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain.
Q51650531Ketamine alters calcium and magnesium in brain tissue following experimental head trauma in rats.
Q34480719Ketamine and phencyclidine: the good, the bad and the unexpected
Q92008296Ketamine inhibits colorectal cancer cells malignant potential via blockage of NMDA receptor
Q48280617Kinetic properties of NMDA receptor-mediated synaptic currents in rat hippocampal pyramidal cells versus interneurones
Q68290501L-(3H) glutamate binding to a membrane preparation from the optic lobe of the giant freshwater prawn de Man
Q34377561L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons
Q48600557LTP induction dependent on activation of Ni2+-sensitive voltage-gated calcium channels, but not NMDA receptors, in the rat dentate gyrus in vitro
Q68280463Lanthanum actions on excitatory amino acid-gated currents and voltage-gated calcium currents in rat dorsal horn neurons
Q33568331Learning and memory: regional changes in N-methyl-D-aspartate receptors in the chick brain after imprinting
Q40483395Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus
Q33980883Ligands for ionotropic glutamate receptors
Q46414116Limiting ischemic injury by inhibition of excitatory amino acid release
Q38327347Links between long-term potentiation and neuropathology. An hypothesis involving calcium-activated proteases
Q42170350Local excitatory network and NMDA receptor activation generate a synchronous and bursting command from the superior colliculus.
Q52213586Localization and developmental expression of the NMDA receptor subunit NR2A in the mammalian retina.
Q48143701Localization of 70-kDa stress protein induction in gerbil brain after ischemia
Q44455413Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine
Q38331610Long-term potentiation and the role of N-methyl-D-aspartate receptors
Q36417958Long-term potentiation during the activity-dependent sharpening of the retinotopic map in goldfish.
Q59066901Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus
Q43814125Low doses of N-methyl-D-aspartate antagonists in superficial laminae of medulla oblongata facilitate wind-up of convergent neurones
Q73542551Low-frequency stimulation of afferent Adelta-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the rat
Q56971343Lowering of extracellular pH suppresses low-Mg2+-induces seizures in combined entorhinal cortex-hippocampal slices
Q41981097MK-801 is a potent nematocidal agent. Characterization of MK-801 binding sites in Caenorhabditis elegans
Q46100504MK-801, an excitatory amino acid antagonist, does not improve neurologic outcome following cardiac arrest in cats
Q34114394Maturation of channels and receptors: consequences for excitability
Q36436727Measurement of neuronal Ca2+ transients using simultaneous microfluorimetry and electrophysiology
Q48666833Mechanism Underlying Protective Effect of MK-801 against NMDA-Induced Neuronal Injury in vivo
Q44391137Mechanism linking NMDA receptor activation to modulation of voltage-gated sodium current in distal retina
Q48735718Mechanism of Inhibition of N-Methyl-d-Aspartate-Stimulated Increases in Free Intracellular Ca2+Concentration by Ethanol
Q48202227Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury
Q42066941Mechanisms of association learning in the post-synaptic neurone
Q34469101Mechanisms of epileptogenicity in focal malformations caused by abnormal cortical development
Q48336425Mechanisms of neuronal damage in brain hypoxia/ischemia: focus on the role of mitochondrial calcium accumulation
Q36472858Mechanisms of synaptic plasticity. Changes in postsynaptic densities and glutamate receptors in chicken forebrain during maturation
Q44604500Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro.
Q48947712Mechanistic distinctions between excitotoxic and acidotic hippocampal damage in an in vitro model of ischemia
Q48594289Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation
Q36673105Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression.
Q73902480Metabotropic glutamate receptor subtypes involved in cardiovascular regulation in the rostral ventrolateral medulla of rats
Q71874354Moderate hypoxia reduces pentylenetetrazol -induced seizures
Q28344399Modulation by permeant ions of Mg(2+) inhibition of NMDA-activated whole-cell currents in rat cortical neurons
Q33609600Modulation of N-methyl-D-aspartate receptor function by glycine transport
Q51756415Modulation of dendritic release of dopamine by N-methyl-D-aspartate receptors in rat substantia nigra.
Q42370931Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus
Q34070607Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus
Q33755785Modulation of the N-methyl-D-aspartate channel by extracellular H+
Q37077439Modulation of the NMDA receptor by polyamines
Q30428213Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment
Q27012689Molecular bases of NMDA receptor subtype-dependent properties
Q35821619Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system
Q41729394Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
Q35075914Molecular characterization of severin from Clonorchis sinensis excretory/secretory products and its potential anti-apoptotic role in hepatocarcinoma PLC cells
Q34383634Molecular components of striatal plasticity: the various routes of cyclic AMP pathways
Q73930281Morphine and methadone have different effects on calcium channel currents in neuroblastoma cells
Q46097874Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro
Q44589652Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons
Q44178866N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties
Q33845727N-methyl-D-aspartate activates different channels than do kainate and quisqualate.
Q48504221N-methyl-D-aspartate increases cytosolic Ca2+ via G proteins in cultured hippocampal neurons
Q37556925N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus
Q34445139N-methyl-D-aspartate receptor antagonist MK-801 prevents apoptosis in rats that have undergone fetal spinal cord transplantation following spinal hemisection
Q34633453N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes
Q37652433N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons
Q33633233N-methyl-D-aspartate receptors contribute to excitatory postsynaptic potentials of cat lateral geniculate neurons recorded in thalamic slices
Q36739414N-methyl-D-aspartate receptors in the retina
Q30412220N-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons
Q37353163NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
Q57169523NMDA Receptor Dependent Long-term Potentiation in Chronic Pain
Q90381145NMDA Receptor Opening and Closing-Transitions of a Molecular Machine Revealed by Molecular Dynamics
Q30700147NMDA Receptors Enhance Spontaneous Activity and Promote Neuronal Survival in the Developing Cochlea
Q44893106NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo
Q43517211NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus
Q71946234NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats
Q35874507NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia
Q30437822NMDA as well as non-NMDA receptor antagonists can prevent the phase-shifting effects of light on the circadian system of the golden hamster
Q28511777NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses
Q44086508NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria
Q46750110NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production.
Q30445749NMDA receptor antagonists block the induction of long-term depression in the hippocampal dentate gyrus of the anesthetized rat
Q37462558NMDA receptor as a newly identified member of the metabotropic glutamate receptor family: clinical implications for neurodegenerative diseases
Q26997407NMDA receptor modulators: an updated patent review (2013-2014)
Q48188111NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A.
Q43650944NMDA receptor subunits GluRepsilon1, GluRepsilon3 and GluRzeta1 are enriched at the mossy fibre-granule cell synapse in the adult mouse cerebellum
Q41173211NMDA receptor-dependent LTD in different subfields of hippocampus in vivo and in vitro
Q48228755NMDA receptor-mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus
Q42465904NMDA receptor-mediated control of presynaptic calcium and neurotransmitter release.
Q44386832NMDA receptor-mediated extracellular adenosine accumulation in rat forebrain neurons in culture is associated with inhibition of adenosine kinase
Q52256869NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling.
Q34315328NMDA receptors, place cells and hippocampal spatial memory
Q36404791NMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a
Q36881384NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity.
Q41202034Neonatal seizures: a clinician's overview
Q83555024Nerve sprouting contributes to increased severity of ventricular tachyarrhythmias by upregulating iGluRs in rats with healed myocardial necrotic injury
Q34398639Neurobiology. Taking apart NMDA receptors
Q87906376Neuronal Cell Death
Q48264459Neuronal Protection and Preservation of Calcium/Calmodulin-Dependent Protein Kinase II and Protein Kinase C Activity by Dextrorphan Treatment in Global Ischemia
Q48274385Neuronal and glial marker proteins in encephalopathy associated with acute liver failure and acute hyperammonemia in the rabbit
Q48787204Neuronal fodrin proteolysis occurs independently of excitatory amino acid-induced neurotoxicity
Q26744759Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder
Q40811557Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway.
Q36587531Neuroprotective activity of a new class of steroidal inhibitors of the N-methyl-D-aspartate receptor
Q48936637Neuroprotective effect of YM90K, a novel AMPA/kainate receptor antagonist, in focal cerebral ischemia in cats
Q34413094Neuroprotective effects of flax lignan against NMDA-induced neurotoxicity in vitro.
Q33835990Neuroprotective effects of gelsolin during murine stroke
Q48939941Neurotoxic glutamate treatment of cultured cerebellar granule cells induces Ca2+ -dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria
Q48136452Neurotoxic potential of three structural analogs of beta-N-oxalyl-alpha,beta-diaminopropanoic acid (beta-ODAP).
Q70144886Neurotransmission. Are there two functional classes of glutamate receptors?
Q42563330Nicergoline inhibits T-type Ca2+ channels in rat isolated hippocampal CA1 pyramidal neurones
Q90582838Nicotinamide reverses behavioral impairments and provides neuroprotection in 3-nitropropionic acid induced animal model ofHuntington's disease: implication of oxidative stress- poly(ADP- ribose) polymerase pathway
Q43698714Nitric oxide produces different actions in different areas of the periaqueductal grey in cats
Q48258112Nitric oxide-mediated spinal disinhibition contributes to the sensitization of primate spinothalamic tract neurons
Q40620954Nitric oxide: a new messenger in the brain
Q44104100Non-ionotropic cross-talk between AMPA and NMDA receptors in rodent hippocampal neurones
Q40938398Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury
Q44188020Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.
Q34175532Opioid poorly-responsive cancer pain. Part 2: basic mechanisms that could shift dose response for analgesia
Q48624759Opposite effects of spermine and arcaine on responses of receptors expressed in Xenopus oocytes
Q34233406Optogenetic activation of cajal-retzius cells reveals their glutamatergic output and a novel feedforward circuit in the developing mouse hippocampus
Q48633744Ornithine decarboxylase activity in cerebral post-ischemic reperfusion damage: effect of methionine sulfoximine
Q48270359Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons
Q72596663Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons
Q55476297Participation of Bcl-2/Bax-alpha in glutamate-induced apoptosis of human glioblastoma cells.
Q48760070Patch clamp analysis of excitatory synaptic currents in granule cells of rat hippocampus
Q40852693Pathophysiological mechanisms of brain damage from status epilepticus
Q73091695Pathophysiology of perinatal brain damage
Q48343471Pb2+ modulates the NMDA-receptor-channel complex
Q48846946Pentylenetetrazol-induced kindling: early involvement of excitatory and inhibitory systems
Q36749244Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+).
Q43591139Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
Q46147208Permeation of Calcium Ions Through Non-NMDA Glutamate Channels in Retinal Bipolar Cells
Q45263360Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones
Q48736258Persistent pulsatile release of glutamate induced by N-methyl-D-aspartate in neonatal rat hippocampal neurones
Q34324706Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers
Q27344585Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders
Q47838192Phospholipase A and Somatostatin Release are Activated in Response to N-Methyl-D-Aspartate Receptor Stimulation in Hypothalamic Neurons in Primary Culture.
Q36356588Phosphorylation of AMPA receptors: mechanisms and synaptic plasticity
Q34114600Phosphorylation processes mediate rapid changes of brain aromatase activity.
Q35796859Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex
Q34539478Physiological effects of sustained blockade of excitatory synaptic transmission on spontaneously active developing neuronal networks--an inquiry into the reciprocal linkage between intrinsic biorhythms and neuroplasticity in early ontogeny
Q61196297Plasticity in the ipsilateral visuotectal projection persists after lesions of one nucleus isthmi inXenopus
Q33721040Plasticity in the tectum of Xenopus laevis: binocular maps.
Q51379172Plateau potential-dependent windup of the response to primary afferent stimuli in rat dorsal horn neurons.
Q37378880Polyamines as Snake Toxins and Their Probable Pharmacological Functions in Envenomation.
Q71059943Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons
Q44002234Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CA1 pyramidal cell dendrites
Q35641409Potential interactions of calcium-sensitive reagents with zinc ion in different cultured cells
Q43684594Potentiation by nitric oxide synthase inhibitor and calcium channel blocker of aspartame-induced antinociception in the mouse formalin test
Q42163757Potentiation of nuclear activator protein-1 DNA binding following brief exposure to N-methyl-D-aspartate in immature cultured rat hippocampal neurons
Q48324129Presence of a non-NMDA glutamate receptor subtype in the sympathetic nervous system of neonatal swine
Q48728242Presynaptic control of subunit composition of NMDA receptors mediating synaptic plasticity
Q45255813Presynaptic glutamate receptors modulate dopamine release from striatal synaptosomes
Q71479801Prevention of nimodipine-induced impairment of learning by the selective sigma ligand PRE-084
Q69716215Proceedings of the British Pharmacological Society. 17th-19th December 1986. Abstracts
Q48830542Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells
Q64290872Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission
Q48109666Properties of the kainate channel in rat brain mRNA injected Xenopus oocytes: ionic selectivity and blockage.
Q38966160Propofol inhibits high glucose-induced PP2A expression in human umbilical vein endothelial cells
Q39323349Prospects for therapeutic mitochondrial transplantation
Q68332165Protective effect of CCK-8 and ceruletide on glutamate-induced neuronal cell death in rat neuron cultures: Possible involvement of CCK-B receptors
Q48473716Protective effect of zonisamide, an antiepileptic drug, against transient focal cerebral ischemia with middle cerebral artery occlusion-reperfusion in rats
Q36515572Protein Kinases and Long-Term Potentiation
Q41471744Protein kinase C in synaptic plasticity: changes in the in situ phosphorylation state of identified pre- and postsynaptic substrates
Q48426839Proteolysis of filament proteins in glial and neuronal cells after in vivo stimulation of hippocampal NMDA receptors
Q40169921Quantitative analysis of tetrapentylammonium-induced blockade of open N-methyl-D-aspartate channels
Q52206809Quantitative and qualitative changes in AMPA receptor expression during spinal cord development
Q73964528Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons
Q45106621Rapid Ca2+ entry through Ca2+-permeable AMPA/Kainate channels triggers marked intracellular Ca2+ rises and consequent oxygen radical production.
Q44639770Rapid alteration of synaptic number and postsynaptic thickening length by NMDA: An electorn microscopic study in the occipital cortex of postnatral rats
Q33507745Rapid, sensitive, and simple method for quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells
Q46460354Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion
Q49134306Recovery from NMDA-induced intracellular acidification is delayed and dependent on extracellular bicarbonate
Q38338178Reduced MK801 binding in neocortical neurons after AAV-mediated transfections with NMDA-R1 antisense cDNA.
Q40739723Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro
Q41826916Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes
Q48626944Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats
Q35214792Regulation and critical role of potassium homeostasis in apoptosis
Q44608451Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists
Q40556180Regulation of N-methyl-D-aspartate (NMDA) receptor function during the rearrangement of developing neuronal connections
Q45863546Regulation of calcium influx by second messengers in rat mast cells.
Q44099011Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation
Q44189392Repetitive application of caffeine sensitizes caffeine-induced Ca2+ release in bullfrog sympathetic ganglion neurons
Q54411068Responses of pyriform cortex neurons to excitatory amino acids: voltage dependence, conductance changes, and effects of divalent cations.
Q36296038Responses of rat P2X2 receptors to ultrashort pulses of ATP provide insights into ATP binding and channel gating
Q37705976Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools
Q45106327Retinal activity regulates developmental switches in functional properties and ifenprodil sensitivity of NMDA receptors in the lateral geniculate nucleus
Q64105799Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage
Q33610838Role of extracellular calcium in anoxic injury of mammalian central white matter
Q55478492Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells.
Q48763738Role of nitric oxide in the cerebellar degeneration during methylmercury intoxication
Q40782597SK channels gate information processing in vivo by regulating an intrinsic bursting mechanism seen in vitro
Q46455731SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala
Q41684419Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death
Q48452357Selective effects of cyanide (100 microM) on the excitatory amino acid-induced elevation of intracellular calcium levels in neuronal culture
Q48301797Selective neurodegeneration induced in rotation-mediated aggregate cell cultures by a transient switch to stationary culture conditions: a potential model to study ischemia-related pathogenic mechanisms
Q48389295Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre-recipient layer) of the mouse hippocampal CA3 subfield
Q39706134Selective vulnerability of brain: new insights from the excitatory synapse
Q59046117Sensory transmitters regulate intracellular calcium in dorsal horn neurons
Q33846439Separate intramolecular targets for protein kinase A control N-methyl-D-aspartate receptor gating and Ca2+ permeability.
Q46876492Serotonergic inhibition of action potential evoked calcium transients in NOS-containing mesopontine cholinergic neurons
Q48138341Serotonergic modulation of the hyperpolarizing spike afterpotential in rat jaw-closing motoneurons by PKA and PKC.
Q51019250Serum ionized magnesium and calcium levels in adult patients with seizures.
Q93060838Signaling from Neural Impulses to Genes
Q41200055Simultaneous measurement of Ca2+ influx and reversal potentials in recombinant N-methyl-D-aspartate receptor channels
Q36411702Single-channel currents from diethylpyrocarbonate-modified NMDA receptors in cultured rat brain cortical neurons
Q42926396Single-molecule patch-clamp FRET microscopy studies of NMDA receptor ion channel dynamics in living cells: revealing the multiple conformational states associated with a channel at its electrical off state
Q48119760Slow excitatory postsynaptic currents mediated by N-methyl-D-aspartate receptors on cultured mouse central neurones
Q48643826Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures
Q42437392Spatiotemporal distribution of intracellular calcium transients during epileptiform activity in guinea pig hippocampal slices
Q48260138Species differences in fodrin proteolysis in the ischemic brain
Q73883928Spinal calmodulin inhibitors reduce N-methyl-D-aspartate- and septide-induced nociceptive behavior
Q46969952Spinal cord neurons are vulnerable to rapidly triggered kainate neurotoxicity in vitro
Q34094017Spinal dorsal horn synaptic plasticity: involvement of group I metabotropic glutamate receptors
Q67963251Spontaneous and NMDA evoked motor rhythms in the neonatal mouse spinal cord: an in vitro study with comparisons to in situ activity
Q44211085Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitro.
Q35870548Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors
Q36417979Stimulation of phosphoinositide turnover by excitatory amino acids. Pharmacology, development, and role in visual cortical plasticity
Q48306489Stimulation with N-methyl-D-aspartate or kainic acid increases cyclic guanosine monophosphate-like immunoreactivity in turtle retina: involvement of nitric oxide synthase
Q48675859Stimulatory and inhibitory effects of N-methyl-D-aspartate on 3H-inositol polyphosphate accumulation in rat cortical slices
Q43638891Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons.
Q68931171Striatal dopamine in motor activation and reward-mediated learning: steps towards a unifying model
Q50760890Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines.
Q27658149Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit
Q48567847Sublethal oxygen-glucose deprivation alters hippocampal neuronal AMPA receptor expression and vulnerability to kainate-induced death
Q34466595Subunit arrangement and function in NMDA receptors
Q33721650Subunit- and site-specific pharmacology of the NMDA receptor channel
Q34054433Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons
Q45113813Suppression of NMDA receptor function using antisense DNA block ocular dominance plasticity while preserving visual responses
Q43638902Suppression of cortical NMDA receptor function prevents development of orientation selectivity in the primary visual cortex.
Q38174853Synaptic Signaling in Learning and Memory
Q48397253Synaptic effects of nitric oxide on enkephalinergic, GABAergic, and glutamatergic networks of the rat periaqueductal gray
Q48487892Synaptic interaction between medullary respiratory neurones during apneusis induced by NMDA-receptor blockade in cat.
Q48291473Synaptic plasticity in ischemia: role of NMDA receptors.
Q36547064Synaptic plasticity in vitro and in silico: insights into an intracellular signaling maze
Q37177396Synaptic receptors and intracellular signal transduction in the cerebellum
Q47925829Synaptic signalling and plasticity: emerging new players
Q34094001Synaptic transmission and plasticity in the superficial dorsal horn
Q41144927Synchronization and cooperative interaction in brain activity
Q73494505Synchronized overproduction of AMPA, kainate, and NMDA glutamate receptors during human spinal cord development
Q35027638Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice
Q36852797Target-specific expression of presynaptic NMDA receptors in neocortical microcircuits
Q34078123Targeting the N-methyl-D-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions
Q57030178The 1980s: D-AP5, LTP and a Decade of NMDA Receptor Discoveries
Q42523382The Effects of NMDA Antagonists on Neuronal Activity in Cat Spinal Cord Evoked by Acute Inflammation in the Knee Joint
Q64244266The Role of NMDA Receptors in Alzheimer's Disease
Q48320720The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.
Q48490959The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat.
Q48169034The effect of intracellular tetraethylammonium ions on the reversal potential of monosynaptic EPSPs and excitatory amino acids in cultured spinal cord neurones
Q44171261The effects of NMDA receptor antagonist MK-801 on lipid peroxidation during focal cerebral ischemia in rats.
Q48620737The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons
Q43289884The effects of the TRPV1 receptor antagonist SB-705498 on trigeminovascular sensitisation and neurotransmission
Q41735278The effects of the modulation of NMDA receptors by homocysteine thiolactone and dizocilpine on cardiodynamics and oxidative stress in isolated rat heart
Q24670299The glutamate story
Q48534911The inositol 1,4,5-trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA
Q40745839The interphase nucleus as a dynamic structure.
Q48707840The involvement of calmodulin and Ca2+/calmodulin-dependent protein kinase II in the circadian rhythms controlled by the suprachiasmatic nucleus
Q48395367The lack of extracellular Na+ exacerbates Ca2+-dependent damage of cultured cerebellar granule cells
Q48636696The medial preoptic nucleus of the hypothalamus modulates activity of nitric oxide sensitive neurons in the midbrain periaqueductal gray
Q43678341The modification of NMDA receptors by visual experience in the rat retina is age dependent
Q48180760The neuropeptide nociceptin is a synaptically released endogenous inhibitor of hippocampal long-term potentiation.
Q42713632The neuroprotective action of dizocilpine (MK-801) in the rat middle cerebral artery occlusion model of focal ischaemia
Q72556549The neuroprotective effect of the glycine site antagonist 3R-(+)-cis-4-methyl-HA966 (L-687,414) in a rat model of focal ischaemia
Q35715095The pathophysiological role and therapeutic implications of platelet activating factor in diseases of aging
Q35738864The pharmacology of vertebrate spinal central pattern generators.
Q36833070The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses
Q48373735The prelimbic cortex muscarinic M₃ receptor-nitric oxide-guanylyl cyclase pathway modulates cardiovascular responses in rats.
Q48445348The protective role of mild acidic pH shifts on synaptic NMDA current in hippocampal slices
Q45120905The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex
Q41253548The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture
Q40622661The role of excitatory amino acid receptors and intracellular messengers in persistent nociception after tissue injury in rats
Q38429588The role of excitotoxic programmed necrosis in acute brain injury
Q36552958The role of immediate early genes in the stabilization of long-term potentiation
Q36472942The role of postsynaptic calcium in the induction of long-term potentiation
Q35195234The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease
Q38821887The structure and function of glutamate receptors: Mg2+ block to X-ray diffraction
Q36409047The α7nACh-NMDA receptor complex is involved in cue-induced reinstatement of nicotine seeking
Q41643140Toward the development of strategies to prevent ischemic neuronal injury. In vitro studies
Q28306010Transducer of regulated CREB and late phase long-term synaptic potentiation
Q30886811Transient neonatal expression of NR2B/2D subunit mRNAs of the N-methyl-D-aspartate receptor in the parasympathetic preganglionic neurons in the rat spinal cord
Q68305698Transmitter-gated currents of GABAergic amacrine-like cells in chick retinal cultures
Q64061191Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
Q64236259Treating Chronic Migraine With Neuromodulation: The Role of Neurophysiological Abnormalities and Maladaptive Plasticity
Q37106939Treatment options and patient perspectives in the management of fibromyalgia: future trends
Q58967294Two channels reduced to one
Q28343366Two distinct oscillatory states determined by the NMDA receptor in rat inferior olive
Q41741236Two forms of hippocampal long-term depression, the counterpart of long-term potentiation
Q48521019Two types of steady-state desensitization of N-methyl-D-aspartate receptor in isolated hippocampal neurones of rat.
Q33854930Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured purkinje neurons
Q48913498Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) potentiate the glutamate-evoked release of arachidonic acid from mouse cortical neurons. Evidence for a cAMP-independent mechanism
Q35686307Visualizing hippocampal synaptic function by optical detection of Ca2+ entry through the N-methyl-D-aspartate channel
Q43517443Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons.
Q27028225Vitreous mediators in retinal hypoxic diseases
Q68475436Voltage sensitivity of NMDA-receptor mediated postsynaptic currents
Q39927618Voltage-dependent gating of NR1/2B NMDA receptors
Q48704494Voltage-dependent properties of dendrites that eliminate location-dependent variability of synaptic input
Q33887012Why do neuroprotective drugs work in animals but not humans?
Q38896665Zinc Deprivation and the Nervous System
Q44104105Zn2+ currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones.
Q81092905[Neurobiological mechanisms of muscle pain referral.].
Q30561237α7nAchR/NMDAR coupling affects NMDAR function and object recognition

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