A model for the molecular requirements of immunoglobulin heavy chain class switching

scientific article published in Nature

A model for the molecular requirements of immunoglobulin heavy chain class switching is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1045074420
P356DOI10.1038/298087A0
P698PubMed publication ID6806666

P2093author name stringL J Harris
K B Marcu
L W Stanton
R B Lang
P2860cites workThe complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolutionQ48414778
The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genesQ48414788
Two Types of DNA Rearrangements in Immunoglobulin GenesQ56169516
Multiple immunoglobulin switch region homologies outside the heavy chain constant region locusQ59071812
An immunoglobulin heavy-chain gene is formed by at least two recombinational eventsQ59084785
5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strainsQ71520598
Studies on the nature and germ-line stability of DNA sequences flanking the mouse immunoglobulin heavy-chain constant-region genesQ71562463
Structure and multiplicity of genes for the human immunoglobulin heavy chain variable regionQ24301627
Human immunoglobulin heavy chain genes: evolutionary comparisons of C mu, C delta and C gamma genes and associated switch sequencesQ24594225
Structure of a rearranged gamma 1 chain gene and its implication to immunoglobulin class-switch mechanismQ35350641
Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic familyQ35350810
Complete nucleotide sequence of mouse imunoglobulin μ gene and comparison with other immunoglobulin heavy chain genesQ35622171
On immunoglobulin heavy chain gene switching: two γ2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressedQ35681792
DNA rearrangements in MPC-11 immunoglobulin heavy chain class-switch variantsQ36294914
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switchQ36356055
Mouse IgA heavy chain gene sequence: implications for evolution of immunoglobulin hinge axonsQ36384107
Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genesQ36416130
Antibody diversity: somatic hypermutation of rearranged VH genesQ36587415
Cloning of human immunoglobulin mu gene and comparison with mouse mu geneQ36605894
Sequences at the somatic recombination sites of immunoglobulin light-chain genesQ39673181
Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain geneQ39693282
Human immunoglobulin D segments encoded in tandem multigenic familiesQ48407051
Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequencesQ48408488
Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genesQ48410772
Recombination events that activate, diversify, and delete immunoglobulin genesQ48411047
Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin gamma 2b-chain geneQ48412294
DNA sequences mediating class switching in alpha-immunoglobulinsQ48412502
A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing eventsQ48412792
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genesQ48412817
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.Q48412824
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.Q48413837
Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA.Q48414120
P433issue5869
P407language of work or nameEnglishQ1860
P304page(s)87-89
P577publication date1982-07-01
P1433published inNatureQ180445
P1476titleA model for the molecular requirements of immunoglobulin heavy chain class switching
P478volume298

Reverse relations

cites work (P2860)
Q35725205A switch region inversion contributes to the aberrant rearrangement of a mu immunoglobulin heavy chain gene in MPC-11 cells
Q59093573A variant translocation places the λ immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma
Q28274427Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes
Q35174996Clonal variants of hybridoma cells that switch isotype at a high frequency
Q39587599Control of immunoglobulin class switch recombination
Q36714632Copy choice mechanism of immunoglobulin heavy-chain switch recombination
Q36319046DNA sequence associated with chromosome translocations in mouse plasmacytomas
Q34963864DNA sequences at immunoglobulin switch region recombination sites
Q37509495DNA sequences near the site of reciprocal recombination between a c-myc oncogene and an immunoglobulin switch region
Q41341371Directed Ig class switch recombination in activated murine B cells.
Q33670970Evolution of B-cell malignancy: pre-B-cell leukemia resulting from MYC activation in a B-cell neoplasm with a rearranged BCL2 gene
Q36261566Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
Q52828179Heterogeneous breakpoints on the immunoglobulin genes are involved in fusion with the 5' region of BCL2 in B-cell tumors.
Q36264990Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma
Q37546858Immunoglobulin gene rearrangements and deletions in human Epstein-Barr virus-transformed cell lines producing different IgG and IgA subclasses
Q40210805Immunoglobulin genes: rearrangement and translocation in human lymphoid malignancy
Q41334777Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells
Q33939848Long identical repeats in the mouse gamma 2b switch region and their implications for the mechanism of class switching
Q40850235Mechanism and regulation of immunoglobulin isotype switching.
Q36890934Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals
Q40677155Molecular Basis of Heavy-Chain Class Switching and Switch Region Deletion in an Abelson Virus-Transformed Cell Line
Q41252914Molecular genetics and lymphoproliferative disorders
Q70477330Molecular genetics of immunoglobulin heavy chain switching
Q37601779Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man.
Q36776415Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch
Q36747802Nonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion
Q35531820Nucleotide sequence and properties of the murine γ3 immunoglobulin heavy chain gene switch region: implications for successive Cγgene switching
Q33934166Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
Q24594717Sequences of human immunoglobulin switch regions: implications for recombination and transcription
Q48395607Simple DNA sequences and dispersed repetitive elements in the vicinity of mouse immunoglobulin K light chain genes
Q39595329The arrangement of immunoglobulin and T cell receptor genes in human lymphoproliferative disorders.
Q41342055The involvement of the candidate proto-oncogene NFKB2/lyt-10 in lymphoid malignancies.
Q52211747The molecular biology of immunoglobulin D.
Q42567576Translocation of c-myc into the immunoglobulin heavy-chain locus in human acute B-cell leukemia. A molecular analysis
Q40567685Unique sequences are interspersed among tandemly repeated elements in the murine gamma 1 switch segment
Q48394462Unusual sequences in the murine immunoglobulin mu-delta heavy-chain region
Q38635860What's new in the application of Southern blot analysis of malignant lymphomas?
Q35693883c-myc Gene rearrangements involving gamma immunoglobulin heavy chain gene switch regions in murine plasmacytomas

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