Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA

Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.HELIYON.2018.E00918
P932PMC publication ID6226601
P698PubMed publication ID30450440

P50authorBronwen ConnorQ89412931
Ruth MonkQ124392033
P2093author name stringKevin Lee
Carsten Rudolph
Johannes Geiger
Kathryn Jones
Sophie Liot
Amy McCaughey-Chapman
Erin Firmin
P2860cites workSuppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNAQ24316383
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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.Q28131663
5'-Triphosphate RNA is the ligand for RIG-IQ28131726
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Six3 controls the neural progenitor status in the murine CNSQ28507238
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Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7bQ48369952
Zic3 induces conversion of human fibroblasts to stable neural progenitor-like cellsQ56777673
New approaches for brain repair—from rescue to reprogrammingQ59070234
Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1aQ59758209
Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors.Q64937041
Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competencyQ83787226
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesisQ28590512
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genomeQ29616636
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Activation of neural cell fate programs toward direct conversion of adult human fibroblasts into tri-potent neural progenitors using OCT-4.Q30585772
Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAsQ33806734
SOX2 functions to maintain neural progenitor identityQ33968061
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Generation of human-induced pluripotent stem cells by a nonintegrating RNA Sendai virus vector in feeder-free or xeno-free conditionsQ34031759
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activationQ34146278
Direct reprogramming of mouse fibroblasts to neural progenitorsQ34180572
Direct reprogramming of fibroblasts into neural stem cells by defined factorsQ34263432
Direct conversion of fibroblasts into stably expandable neural stem cellsQ34263438
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factorQ34280164
Non-viral vectors for gene-based therapyQ34429032
Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogrammingQ34575700
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Probing disorders of the nervous system using reprogramming approachesQ35761135
SOX genes and neural progenitor identityQ36049176
Direct conversion of dermal fibroblasts into neural progenitor cells by a novel cocktail of defined factorsQ36212351
Generation of integration-free and region-specific neural progenitors from primate fibroblastsQ37205314
Current prospects for mRNA gene deliveryQ37307200
Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stabilityQ37416925
Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural ProgenitorsQ37583579
Methods for making induced pluripotent stem cells: reprogramming à la carteQ37845645
Synthetic mRNAs with superior translation and stability properties.Q38072371
Concise review: the involvement of SOX2 in direct reprogramming of induced neural stem/precursor cellsQ38118544
RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications.Q38121503
Neuronal properties, in vivo effects, and pathology of a Huntington's disease patient-derived induced pluripotent stem cellsQ38462208
Evaluating cell reprogramming, differentiation and conversion technologies in neuroscienceQ38838046
Direct Conversion of Cord Blood CD34+ Cells Into Neural Stem Cells by OCT4.Q38875265
Understanding Parkinson's Disease through the Use of Cell ReprogrammingQ39085008
Wnt3a regulates survival, expansion, and maintenance of neural progenitors derived from human embryonic stem cellsQ40083924
Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human FibroblastsQ40485394
Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectorsQ40813551
In Vitro Differentiation of Human Neural Progenitor Cells Into Striatal GABAergic Neurons.Q40942034
Retinoic acid mediates Pax6 expression during in vitro differentiation of embryonic stem cellsQ41058233
Non-Viral Generation of Neural Precursor-like Cells from Adult Human FibroblastsQ41902835
Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypesQ42714345
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e00918
P577publication date2018-11-01
P1433published inHeliyonQ27727019
P1476titleConversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA
P478volume4

Reverse relations

cites work (P2860)
Q90319236Evolving principles underlying neural lineage conversion and their relevance for biomedical translation
Q95579816Receptor variants and the development of centrally acting medications

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