BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway

scientific article published on 16 November 2018

BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1109918971
P356DOI10.1186/S12885-018-5027-9
P932PMC publication ID6240221
P698PubMed publication ID30445932

P50authorBaohua LiQ92466157
P2093author name stringYang Li
Na Li
Fenfen Wang
Qin Chen
Genping Huang
Xuedong Guo
P2860cites workThe role of BKCa in endometrial cancer HEC-1-B cell proliferation and migration.Q52686742
Endometrial cancerQ86100370
Role of KCNMA1 in breast cancerQ31086046
Role of KCNMA1 gene in breast cancer invasion and metastasis to brainQ33488361
ER-α36, a novel variant of ER-α, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathwayQ33747888
Functional insights into modulation of BKCa channel activity to alter myometrial contractilityQ33978637
Caveolin-1 limits the contribution of BKCa channel to MCF-7 breast cancer cell proliferation and invasionQ34685493
BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathwayQ35012494
miR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1.Q35475274
Expression of E-, P- and N-Cadherin and Its Clinical Significance in Cervical Squamous Cell Carcinoma and Precancerous LesionsQ36029105
MaxiK channel partners: physiological impactQ36292595
K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesisQ36356328
AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinomaQ36413463
Expression of Potassium Channels in Uterine Smooth Muscle Cells from Patients with AdenomyosisQ36705487
Expression of the calcium-activated potassium channel in upper and lower segment human myometrium during pregnancy and parturitionQ37161297
Expression and clinical significance of the transforming growth factor-β signalling pathway in endometrial cancerQ37305487
Modulation of BKCa channel gating by endogenous signaling moleculesQ37386448
BKCa promotes growth and metastasis of prostate cancer through facilitating the coupling between αvβ3 integrin and FAK.Q37457834
KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcomeQ37663367
Lymphadenectomy in early stage endometrial cancer: a critical review of the current literatureQ38262562
A novel wnt regulatory axis in endometrioid endometrial cancer.Q38969471
Endometrial Carcinoma: Specific Targeted Pathways.Q39026766
Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines.Q39067088
Molecular interaction and functional coupling between type 3 inositol 1,4,5-trisphosphate receptor and BKCa channel stimulate breast cancer cell proliferationQ39102525
Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathwayQ39853155
Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis.Q39992927
17beta-estradiol at physiological concentrations augments Ca(2+) -activated K+ currents via estrogen receptor beta in the gonadotropin-releasing hormone neuronal cell line GT1-7.Q40061957
Activation of ERK1/2 occurs independently of KRAS or BRAF status in endometrial cancer and is associated with favorable prognosisQ40153836
The antiestrogen tamoxifen activates BK channels and stimulates proliferation of MCF-7 breast cancer cells.Q40197288
KCNMA1 gene amplification promotes tumor cell proliferation in human prostate cancerQ40200569
Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradationQ40626859
Cross-talk between p21-activated kinase 4 and ERα signaling triggers endometrial cancer cell proliferationQ42366599
Regulation of mouse Slo gene expression: multiple promoters, transcription start sites, and genomic action of estrogenQ42826464
Effect of 17β-Estradiol on mRNA Expression of Large- Conductance, Voltage-Dependent, and Calcium-Activated Potassium Channel α and β Subunits in Guinea PigQ44423212
Pregnancy Reprograms Large-Conductance Ca2+-Activated K+ Channel in Uterine Arteries: Roles of Ten-Eleven Translocation Methylcytosine Dioxygenase 1-Mediated Active Demethylation.Q46112847
Aldosterone-induced coronary dysfunction in transgenic mice involves the calcium-activated potassium (BKCa) channels of vascular smooth muscle cellsQ46913432
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
endometrial adenocarcinomaQ18555221
P304page(s)1128
P577publication date2018-11-16
P1433published inBMC CancerQ326300
P1476titleBKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway
P478volume18

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Q90638376Ion Channel Regulation by Sex Steroid Hormones and Vitamin D in Cancer: A Potential Opportunity for Cancer Diagnosis and Therapycites workP2860

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