Tear Proteins Calcium binding protein A4 (S100A4) and Prolactin Induced Protein (PIP) are Potential Biomarkers for Thyroid Eye Disease

scientific article published in Scientific Reports

Tear Proteins Calcium binding protein A4 (S100A4) and Prolactin Induced Protein (PIP) are Potential Biomarkers for Thyroid Eye Disease is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-018-35096-X
P932PMC publication ID6240106
P698PubMed publication ID30446693

P50authorChiaw Ling ChngQ82846346
P2093author name stringYan Gao
Lei Zhou
Siew Kwan Koh
Lu Deng
Louis Tong
Morgan Yang
Lay Leng Seah
Sunny Yu Shen
Roger Wilmer Beuerman
P2860cites workComparative proteomic analysis of tear fluid in Graves' disease with and without orbitopathy.Q51723025
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Identification of Tear Fluid Biomarkers in Dry Eye Syndrome Using iTRAQ Quantitative ProteomicsQ56775850
Prolactin-Induced Protein is a novel biomarker for KeratoconusQ58542449
Correlation of orbital computed tomography and antibodies in patients with hyperthyroid Graves' diseaseQ68522996
Superior limbic keratoconjunctivitis. A prognostic sign for severe Graves ophthalmopathyQ73211649
Superior limbic keratoconjunctivitis: multifactorial mechanical pathogenesisQ74300837
Ocular surface and dry eye in Graves' diseaseQ82975892
Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible proteinQ88664434
Tears as a source of biomarkers for ocular and systemic diseasesQ38123623
S100A proteins as molecular targets in the ocular surface inflammatory diseases.Q38179570
Extrathyroidal manifestations of Graves' disease: a 2014 updateQ38218911
Prolactin-induced protein in breast cancer.Q38282723
Superior limbic keratoconjunctivitis (SLK).Q38765105
Prolactin-Inducible Protein: From Breast Cancer Biomarker to Immune Modulator-Novel Insights from Knockout MiceQ38948324
Long-term follow-up of Graves ophthalmopathy in an incidence cohortQ40994540
Correlation of CT scanning and pathologic features of ophthalmic Graves' diseaseQ41470422
S100 A and B expression in normal and inflamed human limbus.Q42070907
Dry eye syndrome in thyroid-associated ophthalmopathy: lacrimal expression of TSH receptor suggests involvement of TSHR-specific autoantibodiesQ42460915
Changes of lacrimal gland and tear inflammatory cytokines in thyroid-associated ophthalmopathyQ42461690
Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathyQ43853007
Proteomics in autoimmune thyroid eye disease.Q45910808
Tear film profile in patients with active thyroid orbithopathyQ46896899
Analysis of Graves' ophthalmopathy patients' tear protein spectrumQ46966182
Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapyQ24338381
Graves' ophthalmopathyQ28274196
Evaluation of iTRAQ and SWATH-MS for the Quantification of Proteins Associated with Insulin Resistance in Human Duodenal Biopsy SamplesQ28547099
SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye.Q31149662
Altered tear composition in smokers and patients with graves ophthalmopathyQ33259898
Elevation of human alpha-defensins and S100 calcium-binding proteins A8 and A9 in tear fluid of patients with pterygium.Q33402862
Effect of contact lenses on the protein composition in tear film: a ProteinChip studyQ33640459
Cytokines, Graves' disease, and thyroid-associated ophthalmopathyQ33889209
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Gross cystic disease fluid protein-15/prolactin-inducible protein as a biomarker for keratoconus diseaseQ34535960
S100 proteins: structure, functions and pathologyQ34625714
The relationship between Graves' ophthalmopathy and dry eye syndromeQ34871250
S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue.Q35189324
Tears in health and diseaseQ35590404
Proteomics Differentiate Between Thyroid-Associated Orbitopathy and Dry Eye SyndromeQ35591590
Limbal epithelial crypts: a novel anatomical structure and a putative limbal stem cell nicheQ35593144
Biomarker Discovery and Verification of Esophageal Squamous Cell Carcinoma Using Integration of SWATH/MRM.Q35725331
Dysfunctional tear syndrome: dry eye disease and associated tear film disorders - new strategies for diagnosis and treatmentQ36252489
MALDI versus ESI: The Impact of the Ion Source on Peptide Identification.Q36273709
The 2016 European Thyroid Association/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' OrbitopathyQ36811289
Metastasis-inducing S100A4 protein: implication in non-malignant human pathologiesQ37264795
Evaluating Graves' orbitopathyQ38013209
Tear analysis in ocular surface diseasesQ38021534
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
eye diseaseQ3041498
P304page(s)16936
P577publication date2018-11-16
P1433published inScientific ReportsQ2261792
P1476titleTear Proteins Calcium binding protein A4 (S100A4) and Prolactin Induced Protein (PIP) are Potential Biomarkers for Thyroid Eye Disease
P478volume8

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