Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice

scholarly article by Carrie B Coleman et al published 1 November 2018 in Journal of Virology

Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00813-18
P932PMC publication ID6189503
P698PubMed publication ID30089703

P50authorBradley M HaverkosQ87988147
P2093author name stringRosemary Rochford
Roberta Pelanda
Brian M Freed
Nicholas A Smith
Zenggang Pan
Julie Lang
Carrie B Coleman
Lydia A Sweet
P2860cites workElucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry dataQ24605194
Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United StatesQ24617384
Priming of protective T cell responses against virus-induced tumors in mice with human immune system componentsQ24645297
Humanized hemato-lymphoid system miceQ26771440
PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse ModelQ27313748
Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized miceQ27324235
Increased Levels of Plasma Epstein Barr Virus DNA Identify a Poor-Risk Subset of Patients With Advanced Stage Cutaneous T-Cell LymphomaQ30276132
The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a ReassessmentQ30278553
CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infectionQ33374980
A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized miceQ33394809
Current advances in humanized mouse modelsQ33577361
Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cellsQ33929593
Epstein-Barr virus induces erosive arthritis in humanized miceQ34058760
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomasQ34457976
The role of Epstein-Barr virus in cancerQ34574840
Cell type specific infection of Epstein-Barr virus (EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infectionQ35017882
Modeling EBV infection and pathogenesis in new-generation humanized miceQ35040650
Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approachQ35046300
Epstein-Barr virus type 2 latently infects T cells, inducing an atypical activation characterized by expression of lymphotactic cytokines.Q35115666
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivoQ35164726
Deciphering the role of Epstein-Barr virus in the pathogenesis of T and NK cell lymphoproliferationsQ35232848
LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesisQ35242466
Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric populationQ35620244
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infectionQ35641421
EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumorsQ35858022
An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse modelQ36171933
Advances in human B cell phenotypic profilingQ36307080
Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturationQ36626153
Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcriptsQ36696963
Cellular responses to viral infection in humans: lessons from Epstein-Barr virus.Q36766875
Distinction between Epstein-Barr virus type A (EBNA 2A) and type B (EBNA 2B) isolates extends to the EBNA 3 family of nuclear proteins.Q36781303
Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genesQ36782491
Functional and phenotypic characterization of the humanized BLT mouse modelQ37164275
Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infectionQ37493561
The extent of genetic diversity of Epstein-Barr virus and its geographic and disease patterns: a need for reappraisalQ37549340
Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation siteQ37552683
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2Q37579511
Humanized Mouse Models of Clinical DiseaseQ37614202
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomesQ37849461
Plasmablastic lymphoma and related disordersQ37901233
The pathogenesis of Epstein-Barr virus persistent infection.Q38107595
Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disordersQ38179491
T cells modulate Epstein-Barr virus latency phenotypes during infection of humanized miceQ38326876
Humanized mouse models for Epstein Barr virus infectionQ38637726
Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.Q38680794
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific DifferencesQ38808086
Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes.Q39868327
One-step multiplex real-time PCR assay to analyse the latency patterns of Epstein-Barr virus infectionQ40080132
Influence of the Epstein-Barr virus nuclear antigen EBNA 2 on the growth phenotype of virus-transformed B cellsQ40132148
Hydroa vacciniforme-like lymphoma: a chronic EBV+ lymphoproliferative disorder with risk to develop a systemic lymphomaQ40236746
Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential.Q40375799
The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cellQ40843575
Subtypes of Epstein-Barr virus in human immunodeficiency virus-associated non-Hodgkin lymphomaQ41131431
CD5 expression is regulated during human T-cell activation by alternative polyadenylation, PTBP1, and miR-204Q41377606
Epstein-Barr Virus Type 2 Infects T Cells in Healthy Kenyan ChildrenQ41932818
New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areasQ42817224
A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responsesQ43939988
Pathogenic link between hydroa vacciniforme and Epstein-Barr virus-associated hematologic disordersQ44168712
Expression of Epstein-Barr virus nuclear antigens 3, 4, and 6 are altered in cell lines containing B-type virusQ44570865
Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's diseaseQ44983123
Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan childrenQ45407247
The genome of Epstein-Barr virus type 2 strain AG876.Q45419603
Exposure to holoendemic malaria results in elevated Epstein-Barr virus loads in childrenQ45496126
Distribution and localization of Epstein-Barr virus subtypes A and B in AIDS-related lymphomas and lymphatic tissue of HIV-positive patientsQ45876229
Current research on chronic active Epstein-Barr virus infection in Japan.Q51849571
Interleukin-6 is a growth factor for nonmalignant human plasmablasts.Q52021179
Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.Q53592113
Epstein-Barr virus-associated lymphomasQ56930876
Essential role for T cells in human B-cell lymphoproliferative disease development in severe combined immunodeficient miceQ73968462
Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized miceQ89777737
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
immunologyQ101929
P304page(s)JVI.00813-18
P577publication date2018-11-01
P1433published inJournal of VirologyQ1251128
P1476titleEpstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice
P478volume92

Reverse relations

cites work (P2860)
Q89717789B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection
Q91709780Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity
Q58616776PD-1 immunobiology in systemic lupus erythematosus
Q92008485T Lymphocyte Development and Activation in Humanized Mouse Model
Q92860015The Global Landscape of EBV-Associated Tumors

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