Synthesis of 2′-C-cyano-2′-deoxy- and 2′-C-cyano-2′,3′-dideoxy-β-d-arabinofuranosyl nucleosides

article published in 1992

Synthesis of 2′-C-cyano-2′-deoxy- and 2′-C-cyano-2′,3′-dideoxy-β-d-arabinofuranosyl nucleosides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0040-4020(01)88727-5

P50authorSonsoles VelázquezQ42258174
P2093author name stringMaría-José Camarasa
P2860cites workInhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosidesQ28360374
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The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trialQ29620805
Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complexQ34558599
Clinical applications of 3'-azido-2',3'-dideoxythymidine (AZT) and related dideoxynucleosidesQ37995597
Strategies for antiviral therapy in AIDS.Q38172146
Synthesis and antiviral activity of 3'-C-cyano-3'-deoxynucleosidesQ42198618
Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleosideQ44945883
3′--Cyano-3′-deoxythymidineQ59417811
Synthesis of 3'--cyano-3'-deoxy- pentofuranosylthymine nucleosidesQ59417836
Nucleic acid related compounds. 27. "Virtual coupling" of the anomeric proton of cyclic 2'-deoxynucleoside 3',5'-monophosphates. Reassessment of conformation using praseodymium shifts and assignment of H-2',2'' signals by biomimetic deuteration at CQ67586857
Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleosideQ68191232
Radical deoxygenation of tert-alcohols in 2'-branched-chain sugar pyrimidine nucleosides: synthesis and antileukemic activity of 2'-deoxy-2' (S)-methylcytidineQ68670262
Nucleic acid related compounds. 10. 3'-O-Aminoacyl-2'-deoxyadenosines and 2'-O-aminoacyl-3'-deoxyadenosines related to charged transfer ribonucleic acid terminiQ69124983
P433issue9
P304page(s)1683-1694
P577publication date1992-02-01
P1433published inTetrahedronQ1948400
P1476titleSynthesis of 2′-C-cyano-2′-deoxy- and 2′-C-cyano-2′,3′-dideoxy-β-d-arabinofuranosyl nucleosides
P478volume48

Reverse relations

cites work (P2860)
Q59008424Stereoselective synthesis of C-branched nucleoside analogues
Q59417642Synthesis of [1-[3′,5′-Bis-O-(tert-butyldimethylsilyl)-β-d-arabino- and β-d-ribofuranosyl]cytosine]-2′-spiro-5″-(4″-amino-1″,2″-oxathiole-2″,2″-dioxide). Analogues of the highly specific anti-HIV-1 agent TSAO-T

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