α1-Adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure—affinity relationships

scientific article published on 01 May 1997

α1-Adrenoceptor subtype selectivity: Molecular modelling and theoretical quantitative structure—affinity relationships is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0968-0896(97)00007-2
P698PubMed publication ID9208092

P50authorMaria Cristina MenzianiQ42932223
Marina CocchiQ51431831
F FanelliQ55208926
P2093author name stringR Testa
A Leonardi
P G De Benedetti
P2860cites workProjection structure of rhodopsinQ59098567
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Molecular dynamics simulations of m3-muscarinic receptor activation and QSAR analysisQ59614349
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonistsQ59614366
The heuristic-direct approach to theoretical quantitative structure-activity relationship analysis of α1-adrenoceptor ligandsQ59614385
Theoretical quantitative structure—activity relationship analysis on three dimensional models of ligand—m1 muscarinic receptor complexesQ59614399
The heuristic-direct approach to quantitative structure-activity relationship analysisQ59614421
Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular modelQ26778456
Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopyQ27684426
Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtypeQ34245118
Sixth gaddum memorial lecture, National Institute for Medical Research, Mill Hill, January 1977. Presynaptic receptors and their role in the regulation of transmitter releaseQ35176494
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsQ35227301
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscleQ35887984
The probable arrangement of the helices in G protein-coupled receptors.Q40872681
Alpha 1-adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca2+ in smooth muscleQ48205465
Comparison of the effects of clonidine on pre- and postsynaptic adrenoceptors in the rabbit pulmonary artery. Alpha-sympathomimetic inhibition of Neurogenic vasoconstriction.Q52726717
CHARMM: A program for macromolecular energy, minimization, and dynamics calculationsQ53340989
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)809-816
P577publication date1997-05-01
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleAlpha 1-adrenoceptor subtype selectivity: molecular modelling and theoretical quantitative structure-affinity relationships
P478volume5

Reverse relations

cites work (P2860)
Q34241303Alpha 1-adrenergic receptor regulation: basic science and clinical implications
Q44390773Alpha(1) adrenoceptor subtype selectivity. 3D-QSAR models for a new class of alpha(1) adrenoceptor antagonists derived from the novel antipsychotic sertindole
Q48399010Isoxazolo-[3,4-d]-pyridazin-7-(6H)-ones and their corresponding 4,5-disubstituted-3-(2H)-pyridazinone analogues as new substrates for alpha1-adrenoceptor selective antagonists: synthesis, modeling, and binding studies
Q58748163Ligand design for α 1 adrenoceptor subtype selective antagonists
Q74315087Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective alpha1a-receptor antagonists
Q52002335Quantitative structure-activity relationships of alpha1 adrenergic antagonists.
Q42860363Synthesis and Blocking Activities of a New Class of α1‐Adrenoceptor Antagonists
Q59614208The ad hoc supermolecule approach to receptor ligand design
Q47966120Theoretical descriptors in quantitative structure-affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1A receptor antagonists