| human | Q5 |
| P496 | ORCID iD | 0000-0001-7791-1396 |
| P1053 | ResearcherID | E-1703-2016 |
| P69 | educated at | University of Cambridge | Q35794 |
| P108 | employer | AstraZeneca | Q731938 |
| Cambridge Innovation Institute | Q33121715 | ||
| P734 | family name | Crowther | Q21483061 |
| Crowther | Q21483061 | ||
| Crowther | Q21483061 | ||
| P106 | occupation | researcher | Q1650915 |
| Q37527114 | 20 years of GPnotebook: from a medical student project to a national resource |
| Q48395034 | A Drosophila model of Alzheimer's disease |
| Q35605176 | ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism |
| Q43021800 | ANS binding reveals common features of cytotoxic amyloid species |
| Q33799241 | Alzheimer's disease: insights from Drosophila melanogaster models |
| Q42353203 | CCT complex restricts neuropathogenic protein aggregation via autophagy |
| Q47095817 | Central and peripheral circadian clocks and their role in Alzheimer's disease. |
| Q37813223 | Characterisation of serpin polymers in vitro and in vivo. |
| Q36815722 | Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development |
| Q37015387 | Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease |
| Q35648011 | Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster |
| Q52812680 | Drosophila melanogaster as a Model for Studies on the Early Stages of Alzheimer's Disease. |
| Q38067205 | Endoplasmic reticulum dysfunction in neurological disease |
| Q24658387 | Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins |
| Q36017019 | Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity |
| Q51531458 | Expression of the alternative oxidase mitigates beta-amyloid production and toxicity in model systems. |
| Q34138249 | Familial conformational diseases and dementias |
| Q24656549 | Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease |
| Q27346740 | Flyglow: Single-fly observations of simultaneous molecular and behavioural circadian oscillations in controls and an Alzheimer's model |
| Q34390078 | Functional genomics in Drosophila models of human disease |
| Q34072906 | Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response |
| Q46851129 | Insights into amyloid disease from fly models. |
| Q33795575 | Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide |
| Q35802867 | Iron is a specific cofactor for distinct oxidation- and aggregation-dependent Aβ toxicity mechanisms in a Drosophila model |
| Q34575740 | Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation |
| Q112338303 | Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response |
| Q28834095 | Metabolic changes may precede proteostatic dysfunction in a Drosophila model of amyloid beta peptide toxicity |
| Q37663199 | Methods and models in neurodegenerative and systemic protein aggregation diseases |
| Q52722904 | Modeling serpin conformational diseases in Drosophila melanogaster. |
| Q28205298 | Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro |
| Q28275438 | Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB |
| Q28252760 | Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease |
| Q44324243 | Nucleation of alpha 1-antichymotrypsin polymerization |
| Q30317471 | Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies |
| Q48604508 | Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival |
| Q35880697 | Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies |
| Q35615846 | Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies |
| Q89055701 | Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease |
| Q43936085 | Prion-induced toxicity in PrP transgenic Drosophila |
| Q38952139 | Progressive myoclonus epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis). |
| Q28269867 | Protein misfolding and disease: from the test tube to the organism |
| Q35112347 | Retro-inversal of intracellular selected β-amyloid-interacting peptides: implications for a novel Alzheimer's disease treatment |
| Q28473205 | Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo |
| Q41868140 | Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB. |
| Q38313275 | Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis |
| Q34361510 | Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity |
| Q21145889 | Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity |
| Q41997591 | TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant |
| Q39458294 | Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease |
| Q33982824 | The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans. |
| Q37682380 | The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease |
| Q33677217 | The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster |
| Q41015573 | The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster |
| Q36663487 | The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB. |
| Q30374487 | The pro-domains of neurotrophins, including BDNF, are linked to Alzheimer's disease through a toxic synergy with Aβ |
| Q35879851 | Therapeutic targets from a Drosophila model of Alzheimer's disease |
| Q37882046 | Unravelling the twists and turns of the serpinopathies. |
| Q37098068 | Using a Drosophila model of Alzheimer's disease. |
| Q91727975 | Utilizing microphysiological systems and induced pluripotent stem cells for disease modeling: a case study for blood brain barrier research in a pharmaceutical setting |
| Q37474870 | alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies |
| Q36685161 | p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress |
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