Molecular model of human tropoelastin and implications of associated mutations

article published in the Proceedings of the National Academy of Sciences of the United States of America

Molecular model of human tropoelastin and implications of associated mutations is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2018PNAS..115.7338T
P356DOI10.1073/PNAS.1801205115
P932PMC publication ID6048532
P698PubMed publication ID29946030

P50authorGiselle C YeoQ48259812
Anthony S WeissQ57324756
Clair BaldockQ61014577
P2093author name stringMarkus J Buehler
Anna Tarakanova
P2860cites workCell adhesion to tropoelastin is mediated via the C-terminal GRKRK motif and integrin alphaVbeta3Q24652566
Subtle balance of tropoelastin molecular shape and flexibility regulates dynamics and hierarchical assemblyQ27335222
Inflammatory destruction of elastic fibers in acquired cutis laxa is associated with missense alleles in the elastin and fibulin-5 genesQ28288512
Direct observation of structure and dynamics during phase separation of an elastomeric proteinQ30401989
Hydrophobic hydration is an important source of elasticity in elastin-based biopolymersQ30666189
Dissection of human tropoelastin: exon-by-exon chemical synthesis and related conformational studies.Q30883897
Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data.Q33443462
Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteinsQ33718901
NMR studies of localized water and protein backbone dynamics in mechanically strained elastinQ34053784
Applications of elastin-like polypeptides in tissue engineeringQ34109713
Structural disorder and dynamics of elastinQ34114315
Circular dichroism spectra of short, fixed-nucleus alanine helicesQ34386591
Challenges in protein folding simulations: Timescale, representation, and analysisQ34545688
A negatively charged residue stabilizes the tropoelastin N-terminal region for elastic fiber assemblyQ34683347
Shape of tropoelastin, the highly extensible protein that controls human tissue elasticityQ34694179
Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assemblyQ35778914
Elastin-like polypeptides as models of intrinsically disordered proteinsQ36142544
The dissection of human tropoelastin: from the molecular structure to the self-assembly to the elasticity mechanismQ36221129
Cellular interactions with elastinQ36221134
Computational smart polymer design based on elastin protein mutabilityQ36303386
TropoelastinQ37158656
A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary diseaseQ37273940
Drug delivery to solid tumors by elastin-like polypeptidesQ37764989
Tropoelastin--a multifaceted naturally smart materialQ38025493
Applications of elastin-like polypeptides in drug delivery.Q38224685
Intrinsically disordered energy landscapesQ40962797
Total synthesis and expression in Escherichia coli of a gene encoding human tropoelastin.Q40991145
Comparison of five procedures for the purification of insoluble elastinQ43653938
Domain 36 of tropoelastin in elastic fiber formationQ46118180
Tropoelastin interacts with cell-surface glycosaminoglycans via its COOH-terminal domainQ46726568
The molecular basis for the inverse temperature transition of elastinQ47619678
Effect of water on the molecular mobility of elastinQ47634396
Spectroscopic evidence revealing polyproline II structure in hydrophobic, putatively elastomeric sequences encoded by specific exons of human tropoelastinQ48020564
Self-assembled particles of an elastin-like polymer as vehicles for controlled drug release.Q51553120
The protein trinity--linking function and disorder.Q52055900
Structural biology. Versatility from protein disorderQ85009659
Elastic fibres in health and diseaseQ87285382
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)7338-7343
P577publication date2018-07-10
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMolecular model of human tropoelastin and implications of associated mutations
P478volume115

Reverse relations

cites work (P2860)
Q63990932Allysine modifications perturb tropoelastin structure and mobility on a local and global scale
Q90225173Coarse-grained model of tropoelastin self-assembly into nascent fibrils

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