Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication

scientific article published on 03 December 2018

Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1110351816
P356DOI10.1186/S12985-018-1056-X
P932PMC publication ID6276163
P698PubMed publication ID30509291

P50authorTatiana BetakovaQ57499120
P2093author name stringPetra Švančarová
P2860cites workThe crystal structure of the influenza matrix protein M1 at neutral pH: M1-M1 protein interfaces can rotate in the oligomeric structures of M1Q74621944
Nucleocytoplasmic shuttling of influenza A virus proteinsQ26852688
Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomainQ27341132
Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal domain show that M1 is an elongated monomerQ27629317
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNAQ27640425
Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)Q27642013
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
In vitro dissection of the membrane and RNP binding activities of influenza virus M1 proteinQ27863692
Nuclear export of influenza virus ribonucleoproteins: identification of an export intermediate at the nuclear peripheryQ27863697
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A DNA transfection system for generation of influenza A virus from eight plasmidsQ29642855
Characteristics of nucleocytoplasmic transport of H1N1 influenza A virus nuclear export protein.Q30361462
Involvement of an Arginine Triplet in M1 Matrix Protein Interaction with Membranes and in M1 Recruitment into Virus-Like Particles of the Influenza A(H1N1)pdm09 VirusQ30394893
The methionine-aromatic motif plays a unique role in stabilizing protein structureQ30420005
Transcription-inhibition and RNA-binding domains of influenza A virus matrix protein mapped with anti-idiotypic antibodies and synthetic peptidesQ30452201
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virusQ33318082
Association of influenza virus matrix protein with ribonucleoproteinsQ33706147
Influenza virus assembly: effect of influenza virus glycoproteins on the membrane association of M1 proteinQ33914921
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The compensatory G88R change is essential in restoring the normal functions of influenza A/WSN/33 virus matrix protein 1 with a disrupted nuclear localization signalQ34450169
Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independent interaction with hCRM1Q34685189
Influenza virus assembly and buddingQ34913111
Association of influenza virus matrix protein with ribonucleoproteins may control viral growth and morphologyQ35029754
Overlapping signals for translational regulation and packaging of influenza A virus segment 2Q35224411
Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoproteinQ35840594
Identification and characterization of three novel nuclear export signals in the influenza A virus nucleoproteinQ35943693
Two polar residues within C-terminal domain of M1 are critical for the formation of influenza A VirionsQ36380177
An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.Q37275127
Selective incorporation of vRNP into influenza A virions determined by its specific interaction with M1 proteinQ38715617
Differential nucleocytoplasmic shuttling of the nucleoprotein of influenza a viruses and association with host tropismQ39174662
Influenza virus matrix protein is the major driving force in virus budding.Q39593594
Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathwayQ39601251
Influenza A virus replication is inhibited in IFN-λ2 and IFN-λ3 transfected or stimulated cellsQ39640965
The lack of an inherent membrane targeting signal is responsible for the failure of the matrix (M1) protein of influenza A virus to bud into virus-like particles.Q39735600
Influenza virus hemagglutinin and neuraminidase glycoproteins stimulate the membrane association of the matrix protein.Q39876368
Evidence that the CM2 protein of influenza C virus can modify the pH of the exocytic pathway of transfected cells.Q40108973
Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virionsQ40108978
Mutations in matrix protein 1 and nucleoprotein caused human-specific defects in nuclear exportation and viral assembly of an avian influenza H7N1 virusQ40173407
Influence of residue 44 on the activity of the M2 proton channel of influenza A virus.Q40479778
RNA-binding properties of influenza A virus matrix protein M1Q40538600
The host protein CLUH participates in the subnuclear transport of influenza virus ribonucleoprotein complexesQ40559054
The in situ structural characterization of the influenza A virus matrix M1 protein within a virion.Q45383746
Structure of a knockout mutant of influenza virus M1 protein that has altered activities in membrane binding, oligomerisation and binding to NEP (NS2).Q45696228
Influenza virus M1 protein binds to RNA through its nuclear localization signalQ45761700
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectinfluenza A virusQ834390
infectious diseaseQ18123741
P304page(s)187
P577publication date2018-12-03
P1433published inVirology JournalQ7934868
P1476titleConserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication
P478volume15

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