Specific MHC-I Peptides Are Induced Using PROTACs

Specific MHC-I Peptides Are Induced Using PROTACs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2018.02697
P932PMC publication ID6262898
P698PubMed publication ID30524438

P2093author name stringDamien B Ready
Melanie J Patterson
Gregory K Potts
Stephanie M Jensen
P2860cites workA Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I MoleculesQ59356427
Elimination of melanoma by sortase A-generated TCR-like antibody-drug conjugates (TL-ADCs) targeting intracellular melanoma antigen MART-1Q89187704
PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancerQ37065079
Two-headed PROTAC: an effective new tool for targeted protein degradationQ37367308
MHC class I-associated peptides derive from selective regions of the human genomeQ37452154
Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors.Q37644973
Re-examining class-I presentation and the DRiP hypothesisQ37702916
The nature and extent of contributions by defective ribosome products to the HLA peptidome.Q37725183
Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL.Q38817737
Bromodomain inhibitors and cancer therapy: From structures to applicationsQ39027056
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.Q39067631
Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands.Q40264818
Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cellsQ41190385
Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer.Q42775768
The cleavage preference of the proteasome governs the yield of antigenic peptides.Q42943174
Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy.Q44783246
'Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen PrioritizationQ45718710
Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I bindingQ46469492
Gapped sequence alignment using artificial neural networks: application to the MHC class I system.Q47601200
Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I MoleculesQ47718257
Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation.Q48000406
Selective inhibition of BET bromodomainsQ24301009
The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptidesQ24339477
Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix methodQ24815448
Drugging the undruggables: exploring the ubiquitin system for drug developmentQ26752823
BET bromodomain inhibition as a therapeutic strategy to target c-MycQ28247024
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I moleculesQ28248180
Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen PresentationQ30002365
Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilisQ30500770
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancementsQ31145457
Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors.Q31151998
Visual account of protein investment in cellular functionsQ33767436
Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradationQ34083015
Sensitive quantitative predictions of peptide-MHC binding by a 'Query by Committee' artificial neural network approach.Q34276766
Large-scale gene function analysis with the PANTHER classification systemQ34358449
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancerQ34416771
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.Q34478968
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.Q34479551
Catalytic in vivo protein knockdown by small-molecule PROTACs.Q34480735
Protein degradation and the generation of MHC class I-presented peptides.Q34700398
The immune epitope database (IEDB) 3.0.Q35254745
Soluble T-cell receptors produced in human cells for targeted delivery.Q35602230
The proteasome and MHC class I antigen processingQ35967572
Mechanisms of MHC class I-restricted antigen processing and cross-presentationQ36266466
Structural basis of PROTAC cooperative recognition for selective protein degradationQ36306106
NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasetsQ36742441
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P304page(s)2697
P577publication date2018-01-01
P1433published inFrontiers in ImmunologyQ27723748
P1476titleSpecific MHC-I Peptides Are Induced Using PROTACs
P478volume9

Reverse relations

cites work (P2860)
Q96019158PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
Q102371561Proteolysis targeting chimera (PROTAC) for epidermal growth factor receptor enhances anti-tumor immunity in non-small cell lung cancer

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