A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation

scientific article published on 22 November 2018

A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2018.02684
P932PMC publication ID6262026
P698PubMed publication ID30524434

P50authorHannah E ScalesQ62554100
Alan J HayesQ90324075
James M BrewerQ37385291
Gavin R MeehanQ58663480
P2093author name stringPaul Garside
Robert A Benson
Eugene Maraskovsky
Emma Watson
Adriana Baz Morelli
Michio Tomura
Anne Walters
P2860cites workDevelopment and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic miceQ68192458
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunityQ73691187
Th1 and Th2 CD4+ T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivoQ74279868
B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph nodeQ80688189
Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activationQ81469542
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvantQ87416334
Local innate immune responses in the vaccine adjuvant-injected muscleQ28079872
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phasesQ28237805
Visualizing dendritic cell networks in vivoQ29616233
A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivoQ30520629
A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spreadQ30528971
In vivo activation of antigen-specific CD4 T cells.Q34178091
Antigen depot is not required for alum adjuvanticityQ34235031
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivoQ34558048
Monitoring cellular movement in vivo with photoconvertible fluorescence protein "Kaede" transgenic miceQ34802242
ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.Q34848159
Antigen presentation to naive CD4 T cells in the lymph node.Q35187925
Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.Q35863475
Visualizing the first 50 hr of the primary immune response to a soluble antigen.Q35882923
ISCOMATRIX adjuvant for antigen deliveryQ35961178
ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathwayQ36001701
Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.Q36022467
Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortexQ36368559
Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in miceQ36371330
Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and primingQ36371607
Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissuesQ36376423
In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance.Q36403793
Virus-like particle (VLP) lymphatic trafficking and immune response generation after immunization by different routesQ37279007
Mechanisms of action of adjuvantsQ38110539
Development and function of dendritic cell subsetsQ38212449
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph nodeQ38459394
Dendritic cell and antigen dispersal landscapes regulate T cell immunityQ40077299
Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node.Q40302209
In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunityQ40861827
Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.Q41499444
Strategically localized dendritic cells promote rapid T cell responses to lymph-borne particulate antigensQ41530621
Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infectionQ44640663
Nanoparticles target distinct dendritic cell populations according to their sizeQ45732404
Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.Q47161651
Visualization of specific B and T lymphocyte interactions in the lymph nodeQ47892330
The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the folliclesQ48914128
An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthmaQ49066301
INSOLUBLE PRECIPITATES IN DIPHTHERIA AND TETANUS IMMUNIZATIONQ50096277
The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes.Q53622050
Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elementsQ57228054
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P304page(s)2684
P577publication date2018-11-22
P1433published inFrontiers in ImmunologyQ27723748
P1476titleA Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo
P478volume9

Reverse relations

Q91712984Controlled Human Malaria Infection in Semi-Immune Kenyan Adults (CHMI-SIKA): a study protocol to investigate in vivo Plasmodium falciparum malaria parasite growth in the context of pre-existing immunitycites workP2860