| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1110465188 |
| P356 | DOI | 10.1186/S12916-018-1225-1 |
| P932 | PMC publication ID | 6292073 |
| P698 | PubMed publication ID | 30541568 |
| P50 | author | Michael Stumvoll | Q30434795 |
| P2093 | author name string | Werner Kramer | |
| Stephan Martin | |||
| Kerstin Kempf | |||
| Hubert Kolb | |||
| P2860 | cites work | Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men | Q24619063 |
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| Subchronic sleep restriction causes tissue-specific insulin resistance | Q28391901 | ||
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| Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB | Q29619314 | ||
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| The cell biology of systemic insulin function. | Q52603907 | ||
| The genetics of adiposity. | Q52660566 | ||
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| Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood | Q55671354 | ||
| Altering Physical Activity Influences Insulin Responses to Glucose Ingestion in Healthy Adults | Q57457758 | ||
| Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status | Q58698310 | ||
| Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans | Q68602843 | ||
| Insulin dose-response characteristics for suppression of glycerol release and conversion to glucose in humans | Q68908894 | ||
| Regulation of Splanchnic and Peripheral Glucose Uptake by Insulin and Hyperglycemia in Man | Q70237412 | ||
| High fasting insulin levels associated with lower rates of weight gain in persons with normal glucose tolerance: the San Luis Valley Diabetes Study | Q72311177 | ||
| Predictors of weight change in a bi-ethnic population. The San Antonio Heart Study | Q72342704 | ||
| Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults | Q72999974 | ||
| Beneficial effect of diazoxide in obese hyperinsulinemic adults | Q74645788 | ||
| Within- and between-subject variation in commonly measured anthropometric and biochemical variables | Q74672341 | ||
| Basal and insulin-regulated free fatty acid and glucose metabolism in humans | Q79771182 | ||
| Insulin resistance and weight gain in postmenopausal women of diverse ethnic groups | Q80341954 | ||
| A single exercise session increases insulin sensitivity in normal weight and overweight/obese adolescents | Q88452103 | ||
| Insulin therapy, weight gain and prognosis | Q88767498 | ||
| Endothelial Cells: New Players in Obesity and Related Metabolic Disorders | Q91854524 | ||
| Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan | Q33554624 | ||
| Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance | Q33593056 | ||
| Multiple sites of insulin resistance: muscle, liver and adipose tissue | Q33631078 | ||
| Preteen insulin levels interact with caloric intake to predict increases in obesity at ages 18 to 19 years: a 10-year prospective study of black and white girls | Q33798608 | ||
| Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity | Q33830475 | ||
| Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes. | Q33916655 | ||
| Pharmacological agents that directly modulate insulin secretion | Q33964696 | ||
| Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance | Q34137882 | ||
| Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. | Q34191173 | ||
| Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder | Q34195172 | ||
| Insulin resistance associated with lower rates of weight gain in Pima Indians | Q34225463 | ||
| Hyperinsulinemia drives diet-induced obesity independently of brain insulin production | Q34315893 | ||
| Active smoking and risk of metabolic syndrome: a meta-analysis of prospective studies | Q34452303 | ||
| The effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis. | Q34498555 | ||
| In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects | Q34534199 | ||
| Inflammation, metaflammation and immunometabolic disorders | Q34550852 | ||
| Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance | Q34577169 | ||
| Role of dietary fats in modulating cardiometabolic risk during moderate weight gain: a randomized double-blind overfeeding trial (LIPOGAIN study). | Q35070738 | ||
| Banting lecture 2011: hyperinsulinemia: cause or consequence? | Q35612356 | ||
| Fasting Plasma Insulin at 5 Years of Age Predicted Subsequent Weight Increase in Early Childhood over a 5-Year Period-The Da Qing Children Cohort Study | Q35654479 | ||
| Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity | Q36065440 | ||
| Intranasal insulin suppresses food intake via enhancement of brain energy levels in humans | Q36182444 | ||
| Diurnal pattern to insulin secretion and insulin action in healthy individuals | Q36339611 | ||
| Diabetes: have we got it all wrong? Hyperinsulinism as the culprit: surgery provides the evidence | Q36426827 | ||
| Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals | Q36860818 | ||
| Prospective association between fasting NEFA and type 2 diabetes: impact of post-load glucose | Q36862926 | ||
| De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health | Q37088326 | ||
| Insulin sensitivity as an independent predictor of fat mass gain in Hispanic adolescents | Q37400895 | ||
| A longitudinal study of serum insulin and insulin resistance as predictors of weight and body fat gain in African American and Caucasian children | Q37553110 | ||
| Evaluation of glycaemic status in young people with clinical insulin resistance; fasting glucose, fasting insulin or an oral glucose tolerance test? | Q37572825 | ||
| The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation | Q37627659 | ||
| Resistance to type 2 diabetes mellitus: a matter of hormesis? | Q37949231 | ||
| Cross-sectional but not longitudinal associations between non-esterified fatty acid levels and glucose intolerance and other features of the metabolic syndrome. | Q51558544 | ||
| Effect of insulin on oxidative and nonoxidative pathways of free fatty acid metabolism in human obesity. | Q51604953 | ||
| Quantification of the relative impairment in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus. | Q51627070 | ||
| High-fat meal induced postprandial inflammation. | Q38121048 | ||
| Postprandial inflammation: targeting glucose and lipids | Q38231268 | ||
| Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification | Q38372204 | ||
| A Systematic Review and Meta-analysis of the Effect of Gastric Bypass Surgery on Plasma Lipid Levels | Q38554099 | ||
| Socioeconomic status: The missing link between obesity and diabetes mellitus? | Q38668362 | ||
| Long-term exposure to road traffic noise, ambient air pollution, and cardiovascular risk factors in the HUNT and lifelines cohorts | Q38748297 | ||
| Imbalanced insulin action in chronic over nutrition: Clinical harm, molecular mechanisms, and a way forward | Q38770055 | ||
| Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment | Q38872713 | ||
| Energy Metabolism and Ageing in the Mouse: A Mini-Review | Q39001585 | ||
| Glia: silent partners in energy homeostasis and obesity pathogenesis | Q39041911 | ||
| Hyperinsulinemia: a Cause of Obesity? | Q39280021 | ||
| Pre-teen insulin resistance predicts weight gain, impaired fasting glucose, and type 2 diabetes at age 18-19 y: a 10-y prospective study of black and white girls | Q40049640 | ||
| Traffic-related air pollution is associated with cardio-metabolic biomarkers in general residents | Q40367289 | ||
| Relative contribution of health-related behaviours and chronic diseases to the socioeconomic patterning of low-grade inflammation | Q40369672 | ||
| The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration | Q41374692 | ||
| Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men. | Q41740228 | ||
| Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers | Q41743546 | ||
| Insulin action on adipocytes. Evidence that the anti-lipolytic and lipogenic effects of insulin are mediated by the same receptor | Q41811442 | ||
| CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits | Q42367768 | ||
| Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway | Q42411093 | ||
| Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan | Q42512280 | ||
| Insulin resistance and type 2 diabetes | Q42563612 | ||
| A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects | Q43108089 | ||
| The treatment effect of diazoxide on 44 patients with congenital hyperinsulinism | Q44234092 | ||
| Fasting hyperinsulinemia is a predictor of increased body weight gain and obesity in Pima Indian children | Q44496940 | ||
| Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults | Q45370518 | ||
| Metabolic syndrome and Chronic Obstructive Pulmonary Disease (COPD): The interplay among smoking, insulin resistance and vitamin D. | Q45793325 | ||
| Prospective investigation of metabolic characteristics in relation to weight gain in older adults: the Hoorn Study | Q46131438 | ||
| Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats. | Q46305540 | ||
| No evidence of insulin resistance in normal weight vegetarians. A case control study | Q46531824 | ||
| Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes | Q46810133 | ||
| Beyond BMI--phenotyping the obesities | Q47154043 | ||
| The association between depressive symptoms and insulin resistance, inflammation and adiposity in men and women | Q47159698 | ||
| Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain. | Q47177155 | ||
| No effect of inhibition of insulin secretion by diazoxide on weight loss in hyperinsulinaemic obese subjects during an 8-week weight-loss diet | Q47282444 | ||
| On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations | Q47607244 | ||
| Long-term safety of long-acting octreotide in patients with diabetic retinopathy: results of pooled data from 2 randomized, double-blind, placebo-controlled phase 3 studies | Q47632942 | ||
| Microbiota in obesity: interactions with enteroendocrine, immune and central nervous systems | Q47843319 | ||
| Impact of breakfast skipping compared with dinner skipping on regulation of energy balance and metabolic risk | Q47896070 | ||
| The microbiota-gut-brain axis in obesity | Q48138111 | ||
| Adapting to insulin resistance in obesity: role of insulin secretion and clearance | Q49353396 | ||
| Physical Activity Alters Inflammation in Older Adults by Different Intensity Levels. | Q50026820 | ||
| Leptin and the maintenance of elevated body weight | Q50100748 | ||
| Effect of 24-h severe energy restriction on appetite regulation and ad libitum energy intake in lean men and women. | Q51238683 | ||
| Insulin sensitivity at childhood predicts changes in total and central adiposity over a 6-year period. | Q51373176 | ||
| Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. | Q51475854 | ||
| Trends in hyperinsulinemia among nondiabetic adults in the U.S. | Q51486832 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hormone | Q11364 |
| preproinsulin | Q7240673 | ||
| peptide | Q172847 | ||
| obesity | Q12174 | ||
| lifestyle | Q32090 | ||
| P304 | page(s) | 232 | |
| P577 | publication date | 2018-12-13 | |
| P1433 | published in | BMC Medicine | Q4835947 |
| P1476 | title | Insulin translates unfavourable lifestyle into obesity | |
| P478 | volume | 16 |
| Q90108308 | Hormesis in Health and Chronic Diseases |
| Q90139193 | Hyperinsulinemia: An Early Indicator of Metabolic Dysfunction |
| Q64116116 | Pharmacologic adjunctive to insulin therapies in type 1 diabetes: The journey has just begun |
| Q104495318 | The impact of low advanced glycation end products diet on obesity and related hormones: a systematic review and meta-analysis |
| Q90019779 | Type 2 diabetes - unmet need, unresolved pathogenesis, mTORC1-centric paradigm |
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