HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells

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HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1110565512
P356DOI10.1186/S12935-018-0680-2
P932PMC publication ID6290547
P698PubMed publication ID30559605

P2093author name stringLi Yang
Feng Zhang
Ling Liu
Xiao-An Zhang
Chen-Chen Ren
Yan-Nan Chen
P2860cites workHOXB homeobox gene expression in cervical carcinomaQ82418369
Role of TGF-beta1, its receptor TGFbetaRII, and Smad proteins in the progression of colorectal cancerQ82948307
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Cervical cancer screening and treatment training course in El Salvador: experience and lessons learnedQ84611674
Molecular mechanisms of epithelial-mesenchymal transitionQ27013743
Genetic variation in the TGF-β signaling pathway and colon and rectal cancer riskQ30498922
MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9.Q31149519
The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathwaysQ33597010
Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transitionQ33868704
Evolution of the TGF-β signaling pathway and its potential role in the ctenophore, Mnemiopsis leidyiQ34023296
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by DroshaQ34065396
Worldwide burden of cervical cancer in 2008.Q34176394
Loss of HOXC6 expression induces apoptosis in prostate cancer cellsQ34382495
HOXB5 expression in oral squamous cell carcinomaQ34570258
TGF-β1/Smad signaling pathway regulates epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: in vitro and clinical analyses of cell lines and nomadic Kazakh patients from northwest Xinjiang, ChinaQ34611269
Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signalingQ34708273
Homeobox genes: a molecular link between development and cancer.Q35195739
Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.Q35625061
The role of HOXC6 in prostate cancer developmentQ35756663
Longer waiting times for early stage cervical cancer patients undergoing radical hysterectomy are associated with diminished long-term overall survivalQ36205585
Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transitionQ36311752
HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expressionQ36318646
UHRF1 gene silencing inhibits cell proliferation and promotes cell apoptosis in human cervical squamous cell carcinoma CaSki cellsQ37105752
Awareness of cervical cancer risk factors and symptoms: cross-sectional community survey in post-conflict northern UgandaQ37118779
Silencing homeobox C6 inhibits colorectal cancer cell proliferationQ37301782
MicroRNA-147 suppresses human hepatocellular carcinoma proliferation migration and chemosensitivity by inhibiting HOXC6.Q37545085
AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinomaQ37685245
HOXC6 Overexpression Is Associated With Ki-67 Expression and Poor Survival in NPC PatientsQ38642004
HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9.Q38749138
TGF-β/Smad2/3 signal pathway involves in U251 cell proliferation and apoptosisQ38907559
Let‑7a suppresses cell proliferation via the TGF‑β/SMAD signaling pathway in cervical cancerQ39282982
Immunocytochemical detection of homeobox B3, B4, and C6 gene product expression in lung carcinomasQ40751539
Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in childhood medulloblastomas/primitive neuroectodermal tumors.Q41752718
Homeobox B3, B4, and C6 gene product expression in osteosarcomas as detected by immunocytochemistry.Q41757211
DNA Methylation and the HOXC6 Paradox in Prostate CancerQ42585509
Nogo-B promotes the epithelial-mesenchymal transition in HeLa cervical cancer cells via Fibulin-5.Q43656264
Time trends in cervical cancer epidemiology in the Slovak Republic: reflection on the non-implementation of screening with international comparisonsQ45115713
Upregulated Hoxc6 expression is associated with poor survival in gastric cancer patientsQ46299654
N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinomaQ47290074
DKK3 regulates cell proliferation, apoptosis and collagen synthesis in keloid fibroblasts via TGF-β1/Smad signaling pathway.Q51026844
Long noncoding RNA UCA1 modulates breast cancer cell growth and apoptosis through decreasing tumor suppressive miR-143.Q52911989
Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocationsQ60197153
[New classification of malignant tumors TNM (5th edition)]Q78169224
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectgene silencingQ1431332
P304page(s)204
P577publication date2018-01-01
P1433published inCancer Cell InternationalQ1829859
P1476titleHOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells
P478volume18

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cites work (P2860)
Q90324964MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-β signaling pathway
Q90354151Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma
Q93013625The role of contextual signal TGF-β1 inducer of epithelial mesenchymal transition in metastatic lung adenocarcinoma patients with brain metastases: an update on its pathological significance and therapeutic potential
Q64966663miR-877-3p promotes TGF-β1-induced osteoblast differentiation of MC3T3-E1 cells by targeting Smad7.

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