A multicenter, double-blind, randomized, comparison study of the efficacy and safety of tigecycline to imipenem/cilastatin to treat complicated intra-abdominal infections in hospitalized subjects in China

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A multicenter, double-blind, randomized, comparison study of the efficacy and safety of tigecycline to imipenem/cilastatin to treat complicated intra-abdominal infections in hospitalized subjects in China is …
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scholarly articleQ13442814

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P356DOI10.2147/TCRM.S171821
P932PMC publication ID6281154
P698PubMed publication ID30584308

P2093author name stringGang Chen
Ping Li
Ping Yan
Lihong Xu
Michele Wible
Demei Zhu
Yingyuan Zhang
Yijian Chen
Yongjie Zhao
M Anne Hickman
Margaret Tawadrous
Xiajun Xu
P2860cites workInterval estimation for the difference between independent proportions: comparison of eleven methodsQ56475155
Study for Monitoring Antimicrobial Resistance Trends (SMART) in the Asia-Pacific region, 2002-2010Q84502640
A multicenter trial of the efficacy and safety of tigecycline versus imipenem/cilastatin in patients with complicated intra-abdominal infections [Study ID Numbers: 3074A1-301-WW; ClinicalTrials.gov Identifier: NCT00081744].Q24813784
Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of AmericaQ28268745
Two-sided confidence intervals for the single proportion: comparison of seven methodsQ28271313
The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal InfectionQ30275008
Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study.Q30828046
The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical trial dataQ30998307
Efficacy and safety of tigecycline monotherapy vs. imipenem/cilastatin in Chinese patients with complicated intra-abdominal infections: a randomized controlled trialQ33642184
Antibiotic management of complicated intra-abdominal infections in adults: The Asian perspective.Q34829365
Global Assessment of the Activity of Tigecycline against Multidrug-Resistant Gram-Negative Pathogens between 2004 and 2014 as Part of the Tigecycline Evaluation and Surveillance TrialQ37593067
Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial.Q38474221
Clinical response and mortality in tigecycline complicated intra-abdominal infection and complicated skin and soft-tissue infection trialsQ38895819
Optimal Treatment for Complicated Intra-abdominal Infections in the Era of Antibiotic Resistance: A Systematic Review and Meta-Analysis of the Efficacy and Safety of Combined Therapy With MetronidazoleQ38972381
Distribution of ESBLs, AmpC β-lactamases and carbapenemases among Enterobacteriaceae isolates causing intra-abdominal and urinary tract infections in the Asia-Pacific region during 2008-14: results from the Study for Monitoring Antimicrobial ResistaQ40517201
Clinical characteristics and antimicrobial patterns in complicated intra-abdominal infections: a 6-year epidemiological study in southern ChinaQ40783326
A multicentre, open-label, randomized comparative study of tigecycline versus ceftriaxone sodium plus metronidazole for the treatment of hospitalized subjects with complicated intra-abdominal infectionsQ42952452
A 10 year surveillance for antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae in community- and hospital-associated intra-abdominal infections in ChinaQ45275409
In vitro susceptibilities of aerobic and facultatively anaerobic gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: 2005 results from Study for Monitoring Antimicrobial Resistance Trends (SMART).Q46334700
Tigecycline is efficacious in the treatment of complicated intra-abdominal infections.Q50161651
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthospitalizationQ3140971
imipenem/cilastatinQ6004128
P304page(s)2327-2339
P577publication date2018-01-01
P1433published inTherapeutics and Clinical Risk ManagementQ15766913
P1476titleA multicenter, double-blind, randomized, comparison study of the efficacy and safety of tigecycline to imipenem/cilastatin to treat complicated intra-abdominal infections in hospitalized subjects in China
P478volume14

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Q90437573Carbapenems vs tigecycline for the treatment of complicated intra-abdominal infections: A Bayesian network meta-analysis of randomized clinical trialscites workP2860

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