Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine

article

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.MP.4000425
P698PubMed publication ID9857976

P50authorFrancesco BenedettiQ38545632
Enrico SmeraldiQ72933640
P2093author name stringM Catalano
D Di Bella
J Perez
R Zanardi
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectfluvoxamineQ409236
serotoninQ167934
P304page(s)508-511
P577publication date1998-11-01
P1433published inMolecular PsychiatryQ6895973
P1476titlePolymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
P478volume3

Reverse relations

cites work (P2860)
Q340741975-HT-HPA interactions in two models of transgenic mice relevant to major depression
Q342647395-HTTLPR polymorphism impacts task-evoked and resting-state activities of the amygdala in Han Chinese
Q37102263A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment
Q44175726A variable number of tandem repeats in the serotonin transporter gene does not affect the antidepressant response to fluvoxamine
Q44594245Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics
Q44300554Allelic variation in the serotonin transporter promoter affects neuromodulatory effects of a selective serotonin transporter reuptake inhibitor (SSRI).
Q43590767Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease.
Q42485885Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study
Q45956855Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation.
Q31135283Anterior cingulate dysfunction in geriatric depression
Q44598160Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene
Q34088515Antidepressant response and the serotonin transporter gene-linked polymorphic region
Q73179152Antidepressant selection in the postgenomic era
Q44440922Antidepressant-induced mania, rapid cycling and the serotonin transporter gene polymorphism
Q36248038Antidepressant-induced manic conversion: a developmentally informed synthesis of the literature
Q46611107Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene
Q35036686Arguments for the genetic basis of the bipolar spectrum
Q34201923Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study
Q43882789Association between a serotonin transporter promoter region polymorphism and mood response during tryptophan depletion
Q37254532Association between reduced white matter integrity in the corpus callosum and serotonin transporter gene DNA methylation in medication-naive patients with major depressive disorder.
Q33806771Association between serotonin transporter polymorphisms (5-HTTLPR) and the MADRS Dysphoria, Retardation, and Vegetative Subscale scores in the treatment of depression
Q35984750Association of Anxiety Symptoms in Offspring of Bipolar Parents with Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype
Q34348095Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans
Q37074636Association of a functional polymorphism in the serotonin transporter gene with abnormal emotional processing in ecstasy users
Q36018468Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study
Q34316695Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy
Q44634481Association study of a brain‐derived neurotrophic‐factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response
Q44245157Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders
Q42347338Authors' response to "Maternal age as a potential explanation of the role of the L allele of the serotonin transporter gene in anxiety and depression in Asians".
Q47958150BDNF, relative preference, and reward circuitry responses to emotional communication
Q36713109Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study
Q37582410Biological variations in depression and anxiety between East and West.
Q60641089Cautionary note: complex (dys)function of the serotonin transporter
Q51481116Chronic modulation of serotonergic neurotransmission with sertraline attenuates the loudness dependence of the auditory evoked potential in healthy participants.
Q27004154Clinical and molecular genetics of psychotic depression
Q46666799Clinical efficacy of fluvoxamine and functional polymorphism in a serotonin transporter gene on childhood autism
Q37255370Clinical implications of genetic variation in the serotonin transporter promoter region: a review
Q44628774Comorbidity of alcohol dependence with attention-deficit hyperactivity disorder: differences in phenotype with increased severity of the substance disorder, but not in genotype (serotonin transporter and 5-hydroxytryptamine-2c receptor).
Q36983850Correlation of 5-HTT, BDNF and NPSR1 gene polymorphisms with anxiety and depression in asthmatic patients
Q34396635Culture and psychopharmacology
Q33234706Detection and characterization of DNA variants in the promoter regions of hundreds of human disease candidate genes
Q28609425Developing novel treatments for mood disorders: accelerating discovery
Q46197985Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure
Q73384138Differential tissue distribution of the enantiomers of racemic pindolol in the rat
Q43725413Dose-response relationship of selective serotonin reuptake inhibitors treatment-emergent hypomania in depressive disorders
Q94010427Dosing and Monitoring: Children and Adolescents
Q35826495Drug development and use in the elderly: search for the right dose and dosing regimen (Parts I and II).
Q36864041Drug development for CNS disorders: strategies for balancing risk and reducing attrition
Q33655082Early prediction of acute antidepressant treatment response and remission in pediatric major depressive disorder
Q35692269Effectiveness of pindolol plus serotonin uptake inhibitors in depression: a meta-analysis of early and late outcomes from randomised controlled trials
Q44588970Effects of rapid tryptophan depletion on mood and urge to drink in patients with co-morbid major depression and alcohol dependence
Q45049144Effects of serotonin transporter promoter polymorphisms on serotonin function
Q35988130Emerging strategies and applications of pharmacogenomics
Q35040746Ethnic differences in antidepressant response: a prospective multi-site clinical trial
Q34585242Evaluation of the promoter region polymorphism (5-HTTLPR) in the serotonin transporter gene in females with postpartum depression
Q43728696Factors affecting fluvoxamine antidepressant activity: influence of pindolol and 5-HTTLPR in delusional and nondelusional depression
Q35012645Fluoxetine-induced alterations in human platelet serotonin transporter expression: serotonin transporter polymorphism effects
Q35680883From molecular biology to pharmacogenetics: a review of the literature on antidepressant treatment and suggestions of possible candidate genes
Q35709598From monoamines to genomic targets: a paradigm shift for drug discovery in depression
Q37660158From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders
Q27015830From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment
Q43585236Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders
Q34435115Functionally gene-linked polymorphic regions and genetically controlled neurotransmitters metabolism
Q44866370Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.
Q36717718GENetic and clinical predictors of treatment response in depression: the GenPod randomised trial protocol
Q36070320Gender moderates the relationship between mania spectrum and serotonin transporter polymorphisms in depression
Q37971344Gene-environment interaction in major depression and antidepressant treatment response
Q36103263Genetic Variations in the Serotonergic System Mediate a Combined, Weakened Response to SSRI Treatment: A Proposed Model(1,2)
Q34117532Genetic and imaging strategies in obsessive-compulsive disorder: potential implications for treatment development.
Q34530084Genetic factors and treatment of mood disorders
Q34467017Genetic perspectives on the serotonin transporter
Q28543005Genetic prediction of antidepressant drug response and nonresponse in Korean patients
Q36206096Genetics and psychopharmacology: prospects for individualized treatment.
Q43946813Genetics of bipolar disorders
Q24654656Genetics of migraine and pharmacogenomics: some considerations
Q36973699Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response
Q34448376Hepatitis C, interferon a and depression: main physiopathologic hypothesis
Q44487762High platelet-serotonin uptake activity is associated with a rapid response in depressed patients treated with amitriptyline
Q34589831How and why criteria defining moderators and mediators differ between the Baron & Kenny and MacArthur approaches
Q33892493How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findings
Q45081687Identification of single-nucleotide polymorphisms of the human neurokinin 1 receptor gene and pharmacological characterization of a Y192H variant
Q35834300Implications of genetic research on the role of the serotonin in depression: emphasis on the serotonin type 1A receptor and the serotonin transporter
Q33404025Improving the prediction of treatment response in depression: integration of clinical, cognitive, psychophysiological, neuroimaging, and genetic measures.
Q35104346Indianizing psychiatry - Is there a case enough?
Q46385107Individual differences in threat sensitivity predict serotonergic modulation of amygdala response to fearful faces
Q60183059Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications
Q37089253Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications
Q43751897Influence of 5-HTTLPR and TPH variants on illness time course in mood disorders
Q41452983Influence of 5-HTTLPR genotypes on structural and functional connectivity within amygdala-prefrontal cortex circuitry
Q35705858Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review.
Q43870679Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients.
Q46555929Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder
Q43722419Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.
Q43975771Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome
Q50082143Insights and barriers to clinical use of serotonin transporter pharmacogenetics in antidepressant therapy.
Q52891518Interacting effects of the serotonin transporter gene and neuroticism in smoking practices and nicotine dependence.
Q35182336Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population
Q49122438Is 5-HTTLPR linked to the response of selective serotonin reuptake inhibitors in MDD?
Q35111565Is treatment-resistant depression a unique subtype of depression?
Q48041301Kynurenine pathway and white matter microstructure in bipolar disorder
Q30499812Loudness dependence of the auditory evoked potential and response to antidepressants in Chinese patients with major depression
Q44412271Low-dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: a prospective, open-label study
Q43783004Marker gene polymorphisms in hyperkinetic disorder--predictors of clinical response to treatment with methylphenidate?
Q36673952Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
Q28307770Molecular actions and clinical pharmacogenetics of lithium therapy
Q34137588Molecular genetic and family studies in affective disorders: state of the art.
Q87456699Molecular genetic findings in mood disorders
Q34146169Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders
Q46911907Monoaminergic function in major depression. A possibly helpful tool for choosing treatment strategy
Q24792166Neural network analysis in pharmacogenetics of mood disorders
Q26830563Neurogenetics of depression: a focus on reward processing and stress sensitivity
Q34560707Neuroticism but not omega-3 fatty acid levels correlate with early responsiveness to escitalopram
Q34014377New advances in pharmacogenomics
Q43868516New dopamine D2 receptor polymorphisms in rats and association with apomorphine-induced stereotypies
Q43812368No association between dopamine D(2) and D(4) receptor gene variants and antidepressant activity of two selective serotonin reuptake inhibitors
Q33695747Novel strategies for pharmacotherapy of depression
Q33183862Obsessive-Compulsive Disorder, 5-HTTLPR polymorphism and treatment response.
Q44278023Overexpression of an epitope-tagged serotonin transporter in serotonin neurons of the dorsal raphe nucleus using a defective HSV-1 vector
Q35730488Pathophysiologic findings of irritable bowel syndrome in china
Q34726454Personalized medicine in psychiatry: problems and promises
Q48244859Pharmacogenetic analysis of opioid dependence treatment dose and dropout rate.
Q35645901Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing
Q34453112Pharmacogenetic screening and therapeutic drugs
Q36904466Pharmacogenetic studies in depression: a proposal for methodologic guidelines
Q35707704Pharmacogenetics and psychiatry
Q34116530Pharmacogenetics and the serotonin system: initial studies and future directions.
Q34574406Pharmacogenetics in affective disorders
Q35038056Pharmacogenetics in drug development
Q36460262Pharmacogenetics in mood disorder
Q37076472Pharmacogenetics in psychiatry: are we ready for widespread clinical use?
Q34155796Pharmacogenetics of antidepressant response
Q35026088Pharmacogenetics of antidepressants
Q28252209Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
Q34577185Pharmacogenetics of bipolar disorder
Q28216643Pharmacogenetics of lithium prophylaxis in mood disorders: analysis of COMT, MAO-A, and Gbeta3 variants
Q35207551Pharmacogenetics of monoamine transporters
Q34286003Pharmacogenetics: a new diagnostic tool in the management of antidepressive drug therapy
Q35237038Pharmacogenomic strategy for individualizing antidepressant therapy
Q47657960Pharmacogenomic testing in child and adolescent psychiatry: An evidence-based review
Q36019193Pharmacogenomics and systems biology of membrane transporters
Q37678047Pharmacogenomics in psychiatry: the relevance of receptor and transporter polymorphisms
Q90745539Pharmacogenomics of Antidepressant and Antipsychotic Treatment: How Far Have We Got and Where Are We Going?
Q35237236Pharmacogenomics of antidepressant treatment effects
Q35805941Pharmacogenomics of multigenic diseases: sex-specific differences in disease and treatment outcome
Q34134861Pharmacogenomics of psychiatric disorders
Q89329295Pharmacogenomics: A focus on antidepressants and atypical antipsychotics
Q35090217Pharmacogenomics: marshalling the human genome to individualise drug therapy
Q36008105Pindolol augmentation of selective serotonin reuptake inhibitors: accounting for the variability of results of placebo-controlled double-blind studies in patients with major depression.
Q28236448Platelet MAO activity and the 5-HTT gene promoter polymorphism are associated with impulsivity and cognitive style in visual information processing
Q46769754Polymorphisms in the SLC6A4 and HTR2A genes influence treatment outcome following antidepressant therapy
Q36095772Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis.
Q48588111Prediction of remission of depression with clinical variables, neuropsychological performance, and serotonergic/dopaminergic gene polymorphisms.
Q35237042Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder.
Q34543502Psychiatric pharmacogenetics: personalizing psychostimulant therapy in attention-deficit/hyperactivity disorder
Q36593806RNAi-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis
Q44311645Rat strain differences in peripheral and central serotonin transporter protein expression and function
Q32144286Reactivity of serotonin in whole blood: relationship with drug response in obsessive-compulsive disorder.
Q33642413Recent advances in predicting responses to antidepressant treatment
Q34976865Receptor pharmacogenetics: relevance to CNS syndromes
Q73046888Regression to the truth: replication of association in pharmacogenetic studies
Q33945106Research and treatment approaches to depression
Q37206381Response to citalopram is not associated with SLC6A4 genotype in African-Americans and Caucasians with major depression
Q40370839Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder.
Q34871885Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
Q42595600Role of COMT, 5-HT(1A) , and SERT genetic polymorphisms on antidepressant response to Transcranial Magnetic Stimulation
Q35078269Role of pharmacogenomics in individualising treatment with SSRIs
Q37437784SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A.
Q33302969Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research
Q33710367Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans
Q31925050Serotonergic gene expression and depression: implications for developing novel antidepressants.
Q36679249Serotonergic vulnerability and depression: assumptions, experimental evidence and implications.
Q37229060Serotonin Transporter Polymorphism (5-HTTLPR) and Citalopram Effectiveness in Iranian Patients with Major Depressive Disorder
Q36248063Serotonin firing activity as a marker for mood disorders: lessons from knockout mice
Q48048080Serotonin transporter gene (SLC6A4) polymorphisms are associated with response to fluoxetine in south Indian major depressive disorder patients
Q43932430Serotonin transporter gene associated with lithium prophylaxis in mood disorders.
Q34369115Serotonin transporter gene polymorphisms and chronic illness of depression
Q48628669Serotonin transporter genotype and function in relation to antidepressant response in Koreans
Q36491587Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients
Q46531752Serotonin transporter polymorphism and potential response to SSRIs in bulimia nervosa.
Q35750662Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion
Q44628316Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment
Q51905107Serotonin transporter polymorphisms and the occurrence of adverse events during treatment with selective serotonin reuptake inhibitors.
Q43852512Serotonin transporter promoter genotype and illness recurrence in mood disorders
Q33921338Serotonin transporter triallelic genotype and response to citalopram and risperidone in dementia with behavioral symptoms.
Q44357536Serotonin-related gene polymorphisms and central nervous system serotonin function
Q33718672Sleep deprivation in depression: what do we know, where do we go?
Q42771386Step-wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression.
Q46703927Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity
Q46748770Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test
Q61479738Strain-dependent neurochemical and neuroendocrine effects of desipramine, but not fluoxetine or imipramine, in Spontaneously Hypertensive and Wistar–Kyoto rats
Q37911004Surrogate markers of treatment outcome in major depressive disorder
Q83207472Temperature regulation in depression: functional 5HT1A receptor adaptation differentiates antidepressant response
Q48005756The 5-HTTLPR and BDNF polymorphisms moderate the association between uncinate fasciculus connectivity and antidepressants treatment response in major depression
Q60501981The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression
Q51846528The Promise and Reality of Pharmacogenetics in Psychiatry
Q39337639The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in Chinese patients
Q45134478The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression
Q33707758The challenges of psychopharmacogenetics
Q38579133The clinical pharmacology of depressive states
Q36978299The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controls
Q89959099The increasing challenge of the possible impact of ethnicity on psychopharmacology
Q33654737The influence of 5-HTTLPR genotype on the association between the plasma concentration and therapeutic effect of paroxetine in patients with major depressive disorder
Q41452962The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala
Q34663662The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis
Q77805824The pharmacogenomics of depression
Q35757723The pharmacogenomics of selective serotonin reuptake inhibitors.
Q35226451The promise and reality of pharmacogenetics in psychiatry
Q60536553The serotonin transporter and clozapine response
Q34227903The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder
Q48717410Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main effects and interaction.
Q43764520Tryptophan hydroxylase gene associated with paroxetine antidepressant activity.
Q34435136Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs
Q35630029Watson and Crick 50 years on. From double helix to pharmacogenomics
Q85907009[Serotonin transporter gene and stress reactivity in unipolar depression. Role of the HPA system as endophenotype of the SLC6A4 gene]

Search more.