Downregulation of TrkA expression in primary sensory neurons after unilateral lumbar spinal nerve transection and some rescuing effects of nerve growth factor infusion

scientific article published on 01 October 2000

Downregulation of TrkA expression in primary sensory neurons after unilateral lumbar spinal nerve transection and some rescuing effects of nerve growth factor infusion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0168-0102(00)00153-X
P698PubMed publication ID11000445

P50authorXin-Fu ZhouQ47432909
P2093author name stringL Li
Y S Deng
P2860cites workEffects of sciatic nerve resection on L7 spinal roots and dorsal root ganglia in adult catsQ71142619
The consequence of delayed versus immediate nerve repair on the properties of regenerating sensory nerve fibres in the adult ratQ71633310
The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion moleculeQ71803583
Neurones and glial cells of the mouse sciatic nerve undergo apoptosis after injury in vivo and in vitroQ71952388
Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRGQ73629697
Axotomy-induced apoptosis in adult rat primary sensory neuronsQ73834570
Axonal sprouts containing calcitonin gene-related peptide and substance P form pericellular baskets around large diameter neurons after sciatic nerve transection in the ratQ74523565
Inhibition of sensory neuron apoptosis and prevention of loss by NT-3 administration following axotomyQ74595543
Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitroQ79441474
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The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptorQ28295368
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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth FactorQ28609789
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.Q34338664
Peripheral nerve injury triggers noradrenergic sprouting within dorsal root gangliaQ34366097
Nerve growth factor stimulates the development of substance P in sensory gangliaQ36354088
The Synthesis of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal and Cortical Neurons Is Regulated by Specific Transmitter SystemsaQ36927722
Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGFQ38325531
Messenger plasticity in primary sensory neurons following axotomy and its functional implicationsQ40387628
Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons.Q40789379
GFAP immunoreactivity in trigeminal ganglion satellite cells after tooth injury in ratsQ41003353
IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.Q41082017
GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury.Q41214145
The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neuronsQ42454315
TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotoninQ42490267
Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons.Q42578333
Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal ratsQ44232571
NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regenerationQ44747456
Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galaninQ45038370
Expression of mRNA for neurotrophic factors and their receptors in the rat dorsal root ganglion and sciatic nerve following nerve injuryQ46046499
Cell loss in lumbar dorsal root ganglia and transganglionic degeneration after sciatic nerve resection in the rat.Q48343581
Alterations in the ipsi- and contralateral afferent inputs of dorsal horn cells produced by capsaicin treatment of one sciatic nerve in the ratQ48895422
Changes in contralateral protein metabolism following unilateral sciatic nerve sectionQ51739503
Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats.Q53747564
Peripheral and Central Mechanisms of NGF-induced HyperalgesiaQ56980379
Prominent Expression of bFGF in Dorsal Root Ganglia after AxotomyQ57990484
Nerve growth factor regulates expression of neuropeptide genes in adult sensory neuronsQ59060324
Satellite-cell-derived nerve growth factor and neurotrophin-3 are involved in noradrenergic sprouting in the dorsal root ganglia following peripheral nerve injury in the ratQ60706906
Attenuation and recovery of nerve growth factor receptor mRNA in dorsal root ganglion neurons following axotomy.Q64883636
Inflammation near the nerve cell body enhances axonal regenerationQ67985684
Pharmacological effects of nerve growth factor and fibroblast growth factor applied to the transectioned sciatic nerve on neuron death in adult rat dorsal root gangliaQ68683182
Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomyQ69020728
Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injuryQ69227712
Nerve growth factor receptors on normal and injured sensory neuronsQ69335214
Morphological alterations in dorsal root ganglion neurons after peripheral axon injury: association with changes in metabolismQ69963045
Intercostal nerve transection and its effect on the dorsal root ganglion. A quantitative study on thoracic ganglion cell numbers and sizes in the ratQ70586662
Differential expression of the p75 nerve growth factor receptor in glia and neurons of the rat dorsal root ganglia after peripheral nerve transectionQ71059920
P433issue2
P304page(s)183-191
P577publication date2000-10-01
P1433published inNeuroscience ResearchQ15764280
P1476titleDownregulation of TrkA expression in primary sensory neurons after unilateral lumbar spinal nerve transection and some rescuing effects of nerve growth factor infusion
P478volume38

Reverse relations

cites work (P2860)
Q34720130Enteric glia mediate neuronal outgrowth through release of neurotrophic factors.
Q44662043Selective reactions of cutaneous and muscle afferent neurons to peripheral nerve transection in rats.
Q28574005Upregulation of Sodium Channel Nav1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury
Q48493833Upregulation of brain-derived neurotrophic factor in the sensory pathway by selective motor nerve injury in adult rats
Q50484843trkA is expressed in nociceptive neurons and influences electrophysiological properties via Nav1.8 expression in rapidly conducting nociceptors.

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