Alastair W Poole

researcher

Alastair W Poole is …
instance of (P31):
humanQ5

External links are
P856official websitehttps://research-information.bris.ac.uk/en/persons/5fc9b474-6369-4745-839a-6d6bac2c1927
P496ORCID iD0000-0002-0868-297X
P1153Scopus author ID55426270700

P69educated atUniversity of CambridgeQ35794
P108employerUniversity of BristolQ459506
P734family namePooleQ16881336
PooleQ16881336
PooleQ16881336
P735given nameAlastairQ16032077
AlastairQ16032077
P106occupationresearcherQ1650915

Reverse relations

author (P50)
Q34562161Absence of platelet phenotype in mice lacking the motor protein myosin Va
Q80534685Antibody cross-linking of human platelet P-selectin induces calcium entry by a mechanism dependent upon Fcgamma receptor IIA
Q37426198Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex.
Q55411011Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis.
Q84067454Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores
Q28510525Canonical Wnt signaling negatively regulates platelet function
Q92364721Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis
Q42139602Characterization of a novel focal adhesion kinase inhibitor in human platelets.
Q41844730Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity.
Q85748666Comment on "Platelet-derived nucleotides promote tumor cell transendothelial migration and metastasis via P2Y2 receptor" by Schumacher et al
Q45878962Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.
Q84990558Cracking the platelet WIP
Q46630212Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1.
Q41860197Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6.
Q40245456Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.
Q79801159Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function
Q37651042Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.
Q52353228Do platelets promote cardiac recovery post myocardial infarction: Roles beyond occlusive ischemic damage.
Q41809741Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.
Q85657160Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia
Q122951834Epigenetic Regulation of Associates With Myocardial Infarction and Platelet Function
Q42358525Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532].
Q46763613Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism.
Q87181418Focusing on the role of platelets in immune defence against invading pathogens
Q41789528Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.
Q45176611Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.
Q44941572GPIb potentiates GPVI-induced responses in human platelets.
Q33371697Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation
Q40297884Identification of roles for the SNARE-associated protein, SNAP29, in mouse platelets
Q41919298Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.
Q42791781Is JAK2V617F finally off the hook?
Q36979523Isoform-specific functions of protein kinase C: the platelet paradigm.
Q38496267Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.
Q35766245Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling.
Q58695524Loss of the mitochondrial kinase PINK1 does not alter platelet function
Q50044452Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction.
Q58574268Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels
Q85918643Munc13-4 is critical for thrombosis through regulating release of ADP from platelets
Q46252434Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.
Q40467377P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.
Q28505136PKCalpha regulates platelet granule secretion and thrombus formation in mice
Q24301041PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation
Q45933605PKCtheta in platelet activation.
Q33405817PKCα negatively regulates in vitro proplatelet formation and in vivo platelet production in mice.
Q54978412Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation.
Q54346793Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.
Q24300809Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets
Q38369833Platelet Rho GTPases-a focus on novel players, roles and relationships.
Q83433671Platelet Syk is a HIT target
Q42564153Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.
Q38281989Platelet secretion: From haemostasis to wound healing and beyond
Q37982455Platelet signaling-a primer.
Q60300524Platelet-specific deletion of SNAP23 ablates granule secretion, substantially inhibiting arterial and venous thrombosis in mice
Q47859594Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis
Q42795655Protein kinase C alpha enhances sodium–calcium exchange during store-operated calcium entry in mouse platelets
Q36638649Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2
Q37647208Protein kinase Calpha: disease regulator and therapeutic target.
Q41191812Protein kinase Ctheta negatively regulates store-independent Ca2+ entry and phosphatidylserine exposure downstream of glycoprotein VI in platelets.
Q34170640Protein kinase Cα (PKCα) regulates bone architecture and osteoblast activity.
Q43225359RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation.
Q39976986Rapid resensitization of purinergic receptor function in human platelets.
Q44928920Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.
Q37333850RhoG protein regulates platelet granule secretion and thrombus formation in mice.
Q42170536SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.
Q38192676Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?
Q58549008Small GTPases in platelet membrane trafficking
Q84529013Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets
Q45880051Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
Q43162293Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability
Q28584694The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen
Q36276216The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62.
Q43627766The snake venom toxin alboaggregin-A activates glycoprotein VI.
Q45018629Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.
Q54588715Unravelling the different functions of protein kinase C isoforms in platelets.
Q82750335Using zebrafish (Danio rerio) to assess gene function in thrombus formation
Q41831428Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets.
Q24338392WNT-3a modulates platelet function by regulating small GTPase activity

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