Elevated plasma level of soluble triggering receptor expressed on myeloid cells-1 is associated with inflammation activity and is a potential biomarker of thrombosis in primary antiphospholipid syndrome

scientific article published on 07 January 2019

Elevated plasma level of soluble triggering receptor expressed on myeloid cells-1 is associated with inflammation activity and is a potential biomarker of thrombosis in primary antiphospholipid syndrome is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1111243253
P356DOI10.1186/S13075-018-1779-5
P932PMC publication ID6323669
P698PubMed publication ID30616644

P50authorYair MoladQ89678462
P2093author name stringElisheva Pokroy-Shapira
Shirly Oren
Yonatan Edel
Ariela Dortort Lazar
Mohammad Egbaria
Vitaly Kliminski
Yael Pri-Paz Basson
P2860cites workHigh affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin IIQ22254095
Triggering receptor expressed on myeloid cells receptor family modulators: a patent reviewQ26999265
Pathogen recognition and innate immunityQ27861084
TREM-1 amplifies inflammation and is a crucial mediator of septic shockQ28185818
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)Q28292418
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemiaQ28297321
A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study GroupQ29614889
Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patientsQ33341941
Antiphospholipid syndrome: pathogenesis and a window of treatment opportunities in the futureQ33546571
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways.Q33967600
The pathogenesis of the antiphospholipid syndromeQ34332601
A role for Toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndromeQ34364580
Differential regulation of proinflammatory mediators following LPS- and ATP-induced activation of monocytes from patients with antiphospholipid syndrome.Q35133146
TREMs in the immune system and beyondQ35140795
Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studiesQ36013878
The TREM receptor family and signal integrationQ36655903
The TREM-1/DAP12 pathwayQ37055878
Pathogenesis of antiphospholipid syndrome: understanding the antibodiesQ37873720
TREM-1: intracellular signaling pathways and interaction with pattern recognition receptorsQ38056337
Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseasesQ38170160
Clinical Association of a Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) in Patients with Systemic Lupus Erythematosus.Q38896039
β₂-glycoprotein I: a novel component of innate immunity.Q39567484
Toll-like receptor (TLR)-4 mediates anti-β2GPI/β2GPI-induced tissue factor expression in THP-1 cellsQ39629773
A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsisQ42092652
Soluble triggering receptor expressed on myeloid cells-1 is a biomarker of anti-CCP-positive, early rheumatoid arthritisQ42475068
A longitudinal assessment of the natural rate of decline in renal function with age.Q44221820
Elevated synovial expression of triggering receptor expressed on myeloid cells 1 in patients with septic arthritis or rheumatoid arthritis.Q46173307
Primary antiphospholipid syndrome: a low-grade auto-inflammatory disease?Q46309832
Mechanisms of thrombosis in systemic lupus erythematosus and antiphospholipid syndromeQ47311173
Innate immune response gene expression profiles characterize primary antiphospholipid syndrome.Q47743642
Serum soluble triggering receptor on myeloid cells-1 (sTREM-1) is elevated in systemic lupus erythematosus but does not distinguish between lupus alone and concurrent infectionQ47968735
Antiphospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4.Q48074369
Persistent triple antiphospholipid antibody positivity as a strong risk factor of first thrombosis, in a long-term follow-up study of patients without history of thrombosis or obstetrical morbidity.Q51314663
β2-glycoprotein I, lipopolysaccharide and endothelial TLR4: three players in the two hit theory for anti-phospholipid-mediated thrombosis.Q51749454
Update of the guidelines for lupus anticoagulant detection. Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis.Q53190445
Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome.Q54336169
Triggering Receptor Expressed on Myeloid cells-1: a new player in platelet aggregation.Q54364223
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.Q54562289
Anti–β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid raftsQ59140753
TREM-1: a new regulator of innate immunity in sepsis syndromeQ73820244
C-reactive protein in primary antiphospholipid syndromeQ79892833
Lupus anticoagulant is significantly associated with inflammatory reactions in patients with suspected deep vein thrombosisQ80206526
Inflammation in patients with lupus anticoagulant and implications for thrombosisQ81463194
Predictive role of hs-C-reactive protein in patients with antiphospholipid syndromeQ81569473
High-sensitivity C-reactive protein: discriminator between patients with primary and secondary antiphospholipid syndromeQ81992046
Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-Q82132738
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantiphospholipid syndromeQ582207
biomarkerQ864574
thrombosisQ261327
primary antiphospholipid syndromeQ63878006
P304page(s)10
P577publication date2019-01-07
P1433published inArthritis Research and TherapyQ15757229
P1476titleElevated plasma level of soluble triggering receptor expressed on myeloid cells-1 is associated with inflammation activity and is a potential biomarker of thrombosis in primary antiphospholipid syndrome
P478volume21

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cites work (P2860)
Q92307198Inhibition of Triggering Receptor Expressed on Myeloid Cell-1 Alleviates Acute Gouty Inflammation
Q91735435Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE2 pathway

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