Daunorubicin/Cytarabine Liposome: A Review in Acute Myeloid Leukaemia

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Daunorubicin/Cytarabine Liposome: A Review in Acute Myeloid Leukaemia is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S40265-018-1022-3
P932PMC publication ID6314217
P698PubMed publication ID30511323

P2093author name stringHannah A Blair
P2860cites workFirst-in-man study of CPX-351: a liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia.Q35905061
Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML.Q36219674
CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation.Q39066412
In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy.Q39954638
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing miceQ40246743
Phase II, multicenter, randomized trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus intensive salvage therapy in adults with first relapse AML.Q41240646
Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia: A National Population-Based Cohort StudyQ41454879
Biophysical characterization of a liposomal formulation of cytarabine and daunorubicinQ43161582
Leukemia-selective uptake and cytotoxicity of CPX-351, a synergistic fixed-ratio cytarabine:daunorubicin formulation, in bone marrow xenografts.Q43170366
Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessmentQ46931396
Improving combination cancer therapy: the CombiPlex® development platformQ47715078
Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approachQ48305735
The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML.Q54629037
Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML.Q55472969
Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cellsQ84002623
Pharmacokinetics of CPX-351; a nano-scale liposomal fixed molar ratio formulation of cytarabine:daunorubicin, in patients with advanced leukemiaQ84642891
Burden of Acute Myeloid Leukemia Among Older, Newly Diagnosed Patients: Retrospective Analysis of Data From the 2010-2012 Medicare Limited Data SetQ88412258
CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid LeukemiaQ90340566
Scavenger receptor class BI (SR-BI) mediates uptake of CPX-351 into K562 leukemia cellsQ90973882
Healthcare resource utilization and costs in patients with newly diagnosed acute myeloid leukemiaQ91023371
P275copyright licenseCreative Commons Attribution-NonCommercialQ6936496
P2507corrigendum / erratumCorrection to: Daunorubicin/Cytarabine Liposome: A Review in Acute Myeloid LeukaemiaQ60302919
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
acute myeloid leukemiaQ264118
daunorubicin/cytarabineQ62122683
antineoplastic combined chemotherapy protocolsQ66764603
P304page(s)1903-1910
P577publication date2018-12-01
P1433published inDrugsQ3040094
P1476titleDaunorubicin/Cytarabine Liposome: A Review in Acute Myeloid Leukaemia
P478volume78

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cites work (P2860)
Q92784865Induction therapy in acute myeloid leukemia: Is it time to put aside standard 3 + 7?
Q99419129Opto-acoustic synergistic irradiation for vaporization of natural melanin-cored nanodroplets at safe energy levels and efficient sono-chemo-photothermal cancer therapy
Q91741269The Preparation, Determination of a Flexible Complex Liposome Co-Loaded with Cabazitaxel and β-Elemene, and Animal Pharmacodynamics on Paclitaxel-Resistant Lung Adenocarcinoma

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