characterization of a novel norepinephrine transporter PET tracer [F]NS12137 in adult and immature Sprague-Dawley rats

scientific article published on 01 January 2019

characterization of a novel norepinephrine transporter PET tracer [F]NS12137 in adult and immature Sprague-Dawley rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7150/THNO.29740
P932PMC publication ID6332804
P698PubMed publication ID30662550

P50authorAnna KirjavainenQ64438310
Francisco R. López-PicónQ77359956
Merja Haaparanta-SolinQ88737197
P2093author name stringOlof Solin
Sarita Forsback
Dan Peters
Jatta S Takkinen
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Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.Q48451835
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[11C]NS8880, a promising PET radiotracer targeting the norepinephrine transporterQ48602110
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Synthesis of 11C-labeled desipramine and its metabolite 2-hydroxydesipramine: potential radiotracers for PET studies of the norepinephrine transporterQ74037939
The Human BNST: Functional Role in Anxiety and AddictionQ28081635
Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporterQ34332440
Behavioral and psychological symptoms of dementia: a current focus for clinicians, researchers, and caregivers.Q34390162
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Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11CQ34431400
Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.Q34490657
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Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study.Q34874501
Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disordersQ36719172
Neural reserve, neuronal density in the locus ceruleus, and cognitive declineQ36953042
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Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.Q37105874
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Locus (coeruleus) minoris resistentiae in pathogenesis of Alzheimer's diseaseQ38267158
Neuroanatomy and pathology of sporadic Alzheimer's diseaseQ38446411
PET Quantification of the Norepinephrine Transporter in Human Brain with (S,S)-18F-FMeNER-D2.Q39097209
The human locus coeruleus: computer reconstruction of cellular distributionQ41279154
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseasesQ42438205
Noradrenergic changes, aggressive behavior, and cognition in patients with dementiaQ43923762
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brainQ44916198
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Ethnic differences in the prevalence and pattern of dementia-related behaviorsQ46134990
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discoveryQ46503348
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.Q46683965
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupramQ46831650
PET imaging of brain 5-HT1A receptors in rat in vivo with 18F-FCWAY and improvement by successful inhibition of radioligand defluorination with miconazoleQ46925568
Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic MiceQ47580999
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectnorepinephrineQ186242
P304page(s)11-19
P577publication date2019-01-01
P1433published inTheranosticsQ21051383
P1476titleIn vivo characterization of a novel norepinephrine transporter PET tracer [18F]NS12137 in adult and immature Sprague-Dawley rats
P478volume9

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cites work (P2860)
Q92416153Dynamic monitoring of single-terminal norepinephrine transporter rate in the rodent cardiovascular system: A novel fluorescence imaging method
Q92183898Radiosynthesis of the norepinephrine transporter tracer [18 F]NS12137 via copper-mediated 18 F-labelling

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