A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer

A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/MD16120479
P932PMC publication ID6315988
P698PubMed publication ID30513611

P50authorYu-Tang TungQ59684555
Chi-Chien LinQ60962314
Shih-Chao LinQ60962317
P2093author name stringJui-Hsin Su
Te-Chun Hsia
Yu-Chao Lin
Chia-Che Chang
P2860cites workThe relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death.Q52181048
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Linkage of ATM to cell cycle regulation by the Chk2 protein kinaseQ22008502
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DNA damage-induced activation of p53 by the checkpoint kinase Chk2Q28138195
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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpointsQ28266170
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphateQ28301966
Enhanced phosphorylation of p53 by ATM in response to DNA damageQ28609838
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Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cellsQ35142085
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Prodigiosin down-regulates SKP2 to induce p27(KIP1) stabilization and antiproliferation in human lung adenocarcinoma cellsQ36110509
A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects.Q36123720
Neuroprotective Effect of the Marine-Derived Compound 11-Dehydrosinulariolide through DJ-1-Related Pathway in In Vitro and In Vivo Models of Parkinson's Disease.Q36168877
Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cellsQ36248410
Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cellsQ37148064
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Nivolumab dose selection: challenges, opportunities, and lessons learned for cancer immunotherapyQ37414886
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Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9-22: effects on the cell apoptosis through mitochondrial-related and ER stress pathwayQ39299160
Neuroprotection by marine-derived compound, 11-dehydrosinulariolide, in an in vitro Parkinson's model: a promising candidate for the treatment of Parkinson's disease.Q39436892
ATM activation and signaling under hypoxic conditions.Q39921855
Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent mannerQ40345113
Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic miceQ44667616
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectdrug discoveryQ1418791
P304page(s)479
P577publication date2018-11-30
P1433published inMarine DrugsQ2122804
P1476titleA Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer
P478volume16

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Q90087549Identification of candidate genes associated with the pathogenesis of small cell lung cancer via integrated bioinformatics analysiscites workP2860

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