Discontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo controlled trial

scientific article published in PLoS ONE

Discontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo controlled trial is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0206907
P932PMC publication ID6312229
P698PubMed publication ID30596666

P50authorHeiner GrosskurthQ39062919
P2093author name stringAndrew Nunn
Jonathan Levin
Paula Munderi
Andrew Abaasa
Zacchaeus Anywaine
Ronnie Kasirye
Joseph Kayiira Lutaakome
P2860cites workExit interviews administered to patients participating in the COSTOP placebo controlled randomised trial in Uganda.Q52855669
Lower early mortality rates among patients receiving antiretroviral treatment at clinics offering cotrimoxazole prophylaxis in MalawiQ62487042
Safety and efficacy of co-trimoxazole for treatment and prevention of Plasmodium falciparum malaria: a systematic reviewQ21133667
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and designQ24569560
Cotrimoxazole Prophylaxis Discontinuation among Antiretroviral-Treated HIV-1-Infected Adults in Kenya: A Randomized Non-inferiority TrialQ28552031
Cost effectiveness analysis of clinically driven versus routine laboratory monitoring of antiretroviral therapy in Uganda and ZimbabweQ28730357
Haematological changes in adults receiving a zidovudine-containing HAART regimen in combination with cotrimoxazole in Côte d'IvoireQ33368355
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trialQ33587553
Reducing mortality with cotrimoxazole preventive therapy at initiation of antiretroviral therapy in South AfricaQ34209707
Trends in AIDS Deaths, New Infections and ART Coverage in the Top 30 Countries with the Highest AIDS Mortality Burden; 1990-2013.Q35684087
Safety of discontinuing cotrimoxazole prophylaxis among HIV infected adults on anti-retroviral therapy in Uganda (COSTOP trial): DesignQ35973095
Incidence of malaria by cotrimoxazole use in HIV-infected Ugandan adults on antiretroviral therapy: a randomised, placebo-controlled studyQ36517673
Global Policy Review of Recommendations on Cotrimoxazole Prophylaxis among People Living with HIV.Q38217764
Co-trimoxazole prophylaxis in adults, including pregnant women, with HIV: a systematic review and meta-analysisQ38596372
HIV-infected ugandan adults taking antiretroviral therapy with CD4 counts >200 cells/μL who discontinue cotrimoxazole prophylaxis have increased risk of malaria and diarrheaQ38868223
Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohortQ38872771
Feasibility and effectiveness of cotrimoxazole prophylaxis for HIV-1-infected adults attending an HIV/AIDS clinic in UgandaQ38879309
The pros and cons of noninferiority trialsQ39361105
Plasmodium falciparum cross-resistance between trimethoprim and pyrimethamineQ43758891
Early chemoprophylaxis with trimethoprim-sulphamethoxazole for HIV-1-infected adults in Abidjan, Côte d'Ivoire: a randomised trial. Cotrimo-CI Study GroupQ43836224
Skin reactions to co-trimoxazoleQ44368559
Does cotrimoxazole prophylaxis for the prevention of HIV-associated opportunistic infections select for resistant pathogens in Kenyan adults?Q47877517
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectUgandaQ1036
placeboQ269829
P304page(s)e0206907
P577publication date2018-01-01
P1433published inPLOS OneQ564954
P1476titleDiscontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo controlled trial
P478volume13

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