Tracking sex-dependent differences in a mouse model of CLN6-Batten disease

scientific article published on 21 January 2019

Tracking sex-dependent differences in a mouse model of CLN6-Batten disease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1111576868
P356DOI10.1186/S13023-019-0994-8
P932PMC publication ID6341540
P698PubMed publication ID30665444

P50authorTyler B JohnsonQ59819663
Jill M WeimerQ89194542
P2093author name stringAlexander D Kloth
Jacob T Cain
Katherine A White
Samantha S Davis
McKayla J Poppens
Rachel Laufmann
P2860cites workEtiologies underlying sex differences in Autism Spectrum DisordersQ22251432
Females experience a more severe disease course in Batten diseaseQ24602745
Mutations in a novel CLN6-encoded transmembrane protein cause variant neuronal ceroid lipofuscinosis in man and mouseQ24633059
Spectrum of mutations in the Batten disease gene, CLN3Q24678552
Sex differences in Parkinson's diseaseQ27025107
A murine model of variant late infantile ceroid lipofuscinosis recapitulates behavioral and pathological phenotypes of human diseaseQ27303003
Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease ConsortiumQ28288921
Retinal oxidation, apoptosis and age- and sex-differences in the mnd mutant mouse, a model of neuronal ceroid lipofuscinosisQ28511611
Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9Q28591663
Estrogen actions in the central nervous systemQ33658556
Sex differences in cognitive impairment and Alzheimer's diseaseQ33864547
Immunosuppression alters disease severity in juvenile Batten disease miceQ34142898
Novel mutations in the CLN6 gene causing a variant late infantile neuronal ceroid lipofuscinosis.Q34188178
Spectrum of CLN6 mutations in variant late infantile neuronal ceroid lipofuscinosisQ34207198
Genetic basis and phenotypic correlations of the neuronal ceroid lipofusinoses.Q34336077
Correlations between genotype, ultrastructural morphology and clinical phenotype in the neuronal ceroid lipofuscinosesQ34427575
Sex bias in neuroscience and biomedical researchQ34433270
The neuronal ceroid-lipofuscinosesQ35045618
Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosisQ35088229
Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and genderQ35237718
Current state of clinical and morphological features in human NCL.Q35681059
Sex differences in microglial colonization of the developing rat brainQ35812893
Electroclinical spectrum of the neuronal ceroid lipofuscinoses associated with CLN6 mutationsQ35904791
Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implicationsQ36102771
Sex Differences in the Study of Neurological IllnessesQ36453477
Sex and systemic lupus erythematosus: the role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cellsQ36560125
Gonadal hormones and the control of reactive gliosis.Q37991787
NCL disease mechanismsQ38109408
Sex differences in attention Deficit Hyperactivity Disorder: candidate genetic and endocrine mechanisms.Q38200373
Inflammatory Response in the CNS: Friend or Foe?Q38790379
Sex differences in microglial phagocytosis in the neonatal hippocampusQ38877499
The importance of studying sex differences in disease: The example of multiple sclerosisQ39015338
The neuronal ceroid-lipofuscinoses (Batten disease): comparative aspectsQ40538599
Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormonesQ43268433
Blindness in South Hampshire sheep: a neuronal ceroidlipofuscinosisQ44423488
Cell cycle arrest in Batten disease lymphoblast cellsQ44738253
Sex differences in the phagocytic and migratory activity of microglia and their impairment by palmitic acidQ47579436
Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone.Q48140133
Gender differences in risk factors for transition from mild cognitive impairment to Alzheimer's disease: A CREDOS study.Q53355173
Neuronal ceroid lipofuscinosesQ56566989
Variant late infantile ceroid lipofuscinoses associated with novel mutations in CLN6Q60232624
Short-Term Administration of Mycophenolate Is Well-Tolerated in CLN3 Disease (Juvenile Neuronal Ceroid Lipofuscinosis)Q64044847
Gonadal hormones down-regulate reactive gliosis and astrocyte proliferation after a penetrating brain injuryQ72785086
Cln3(Deltaex7/8) knock-in mice with the common JNCL mutation exhibit progressive neurologic disease that begins before birthQ78358538
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)19
P577publication date2019-01-21
P1433published inOrphanet Journal of Rare DiseasesQ15756117
P1476titleTracking sex-dependent differences in a mouse model of CLN6-Batten disease
P478volume14

Reverse relations

Q96816294A tailored Cln3Q352X mouse model for testing therapeutic interventions in CLN3 Batten diseasecites workP2860

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