| scholarly article | Q13442814 |
| P50 | author | Subramanya Srikantan | Q56529375 |
| Karthik Ramachandran | Q89474682 | ||
| Joshua J Woods | Q89624714 | ||
| P2093 | author name string | Muniswamy Madesh | |
| Peter B Stathopulos | |||
| Santhanam Shanmughapriya | |||
| Manfred Thomas | |||
| Akshay Kumar | |||
| Sarah R Nathan | |||
| Neeharika Nemani | |||
| Edmund Carvalho | |||
| Justin J Wilson | |||
| MengQi Zhang | |||
| P2860 | cites work | MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake | Q24294670 |
| MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival | Q24301822 | ||
| MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism | Q24304898 | ||
| Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter | Q24306825 | ||
| A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter | Q24306850 | ||
| MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity | Q24338031 | ||
| EMRE is an essential component of the mitochondrial calcium uniporter complex | Q24339589 | ||
| STIM proteins: dynamic calcium signal transducers | Q24633618 | ||
| The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications | Q26824036 | ||
| MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics | Q28116180 | ||
| The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake | Q28118964 | ||
| Mitochondrial calcium transport: physiological and pathological relevance | Q28247285 | ||
| The geometry of intercalation complex of antitumor mitoxantrone and ametantrone with DNA: molecular dynamics simulations | Q28279353 | ||
| MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling | Q28486060 | ||
| NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter | Q28568581 | ||
| Calcium signalling: dynamics, homeostasis and remodelling | Q29547635 | ||
| Regulation of cell death: the calcium-apoptosis link | Q29615554 | ||
| A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein | Q29616188 | ||
| Calcium signaling | Q29617338 | ||
| The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability | Q30274561 | ||
| An expanded palette of genetically encoded Ca²⁺ indicators | Q30533809 | ||
| Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts. | Q30886115 | ||
| J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential | Q33539001 | ||
| Mitochondrial transport of cations: channels, exchangers, and permeability transition. | Q33744633 | ||
| Molecular basis of calcium signaling in lymphocytes: STIM and ORAI | Q33819323 | ||
| Minocycline chelates Ca2+, binds to membranes, and depolarizes mitochondria by formation of Ca2+-dependent ion channels | Q33874297 | ||
| Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex | Q34108154 | ||
| Oxygen-bridged dinuclear ruthenium amine complex specifically inhibits Ca2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes | Q34464960 | ||
| The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart | Q35836414 | ||
| SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore | Q36118077 | ||
| Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter | Q36327478 | ||
| Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. | Q36490057 | ||
| Architecture of the mitochondrial calcium uniporter | Q36922063 | ||
| Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization | Q37087781 | ||
| KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients | Q37313183 | ||
| MICU1 motifs define mitochondrial calcium uniporter binding and activity. | Q37574309 | ||
| Calcium uptake mechanisms of mitochondria. | Q37676371 | ||
| Mitochondrial calcium homeostasis as potential target for mitochondrial medicine | Q37907474 | ||
| Ca2+ as a second messenger within mitochondria of the heart and other tissues | Q37918891 | ||
| Mitochondria as sensors and regulators of calcium signalling | Q38031124 | ||
| The molecular era of the mitochondrial calcium uniporter | Q38569106 | ||
| Metal-based drugs that break the rules | Q38714812 | ||
| Enjoy the Trip: Calcium in Mitochondria Back and Forth | Q38825617 | ||
| Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter | Q38888678 | ||
| Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells. | Q39265638 | ||
| Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations | Q39445564 | ||
| Arene ruthenium complexes as anticancer agents | Q39706669 | ||
| Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells | Q39900189 | ||
| The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter. | Q40217577 | ||
| Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions | Q40322945 | ||
| Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells. | Q40862150 | ||
| Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration | Q40963531 | ||
| DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter | Q41024258 | ||
| Mitoxantrone-DNA binding and the induction of topoisomerase II associated DNA damage in multi-drug resistant small cell lung cancer cells | Q41716421 | ||
| The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition | Q41822328 | ||
| A Red-Light-Activated Ruthenium-Caged NAMPT Inhibitor Remains Phototoxic in Hypoxic Cancer Cells. | Q41916219 | ||
| MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter | Q41976396 | ||
| Evolutionary diversity of the mitochondrial calcium uniporter | Q42128299 | ||
| Mitochondrial pharmacology turns its sights on the Ca2+ uniporter. | Q42363322 | ||
| The mitochondrial calcium uniporter is a highly selective ion channel. | Q44737530 | ||
| Heart transplantation in a patient with multiple sclerosis and mitoxantrone-induced cardiomyopathy | Q44890279 | ||
| Exploration of the medical periodic table: towards new targets | Q45753652 | ||
| Inhibition of the mitochondrial calcium uniporter prevents IL-13 and allergen-mediated airway epithelial apoptosis and loss of barrier function. | Q46244373 | ||
| Inhibition of the mitochondrial calcium uniporter inhibits Aβ-induced apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress in cultured microglia | Q46302504 | ||
| Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity. | Q46408932 | ||
| Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening | Q47935016 | ||
| Bis(thiosemicarbazone) Complexes of Cobalt(III). Synthesis, Characterization, and Anticancer Potential | Q48137381 | ||
| Synthetic Methods for the Preparation of a Functional Analogue of Ru360, a Potent Inhibitor of Mitochondrial Calcium Uptake | Q48185714 | ||
| Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor | Q50173765 | ||
| A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers. | Q52721390 | ||
| Dinuclear nitrido-bridged ruthenium complexes bearing diimine ligands. | Q53034239 | ||
| Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells. | Q53880972 | ||
| X-ray and cryo-EM structures of the mitochondrial calcium uniporter | Q57181877 | ||
| Cryo-EM structure of a fungal mitochondrial calcium uniporter | Q59055925 | ||
| Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters | Q59055935 | ||
| Interactions of antitumor agents ametantrone∗∗Trade name for the salt of 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione (Fig. 1, I). Abbreviations: HAQ, ANT; NSC-287513. and mitoxantrone (novatrone)††Trade name for the sa | Q62590633 | ||
| Structural dependency of the inhibitory action of benzodiazepines and related compounds on the mitochondrial Na+-Ca2+ exchanger | Q67976852 | ||
| Decoding of cytosolic calcium oscillations in the mitochondria | Q71955698 | ||
| Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window | Q84832264 | ||
| Ruthenium chalcogenonitrosyl and bridged nitrido complexes containing chelating sulfur and oxygen ligands | Q86404569 | ||
| Cryo-EM structure of a mitochondrial calcium uniporter | Q89324271 | ||
| Molecular regulation of MCU: Implications in physiology and disease | Q89446590 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| reperfusion injury | Q1413991 | ||
| hypoxia | Q105688 | ||
| P304 | page(s) | 153-166 | |
| P577 | publication date | 2019-01-04 | |
| P1433 | published in | ACS Central Science | Q27726586 |
| P1476 | title | A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury | |
| P478 | volume | 5 |
| Q89787743 | A High-Throughput Screening Identifies MICU1 Targeting Compounds |
| Q99708304 | A looming role of mitochondrial calcium in dictating the lung epithelial integrity and pathophysiology of lung diseases |
| Q89623188 | Cardiolipin Structure and Oxidation Are Affected by Ca2+ at the Interface of Lipid Bilayers |
| Q92494358 | Contribution of Mitochondrial Ion Channels to Chemo-Resistance in Cancer Cells |
| Q91223830 | Endoplasmic reticulum Ca2+ release causes Rieske iron-sulfur protein-mediated mitochondrial ROS generation in pulmonary artery smooth muscle cells |
| Q94554577 | MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth |
| Q89862880 | MCUB and mitochondrial calcium uptake - modeling, function, and therapeutic potential |
| Q90381277 | Mitochondrial Calcium Uniporter Structure and Function in Different Types of Muscle Tissues in Health and Disease |
| Q91589499 | Mitochondrial calcium uniporter complex modulation in cancerogenesis |
| Q100509563 | Pharmacological inhibition of the mitochondrial Ca2+ uniporter: Relevance for pathophysiology and human therapy |
| Q90002593 | The cell-permeable mitochondrial calcium uniporter inhibitor Ru265 preserves cortical neuron respiration after lethal oxygen glucose deprivation and reduces hypoxic/ischemic brain injury |
| Q94469421 | The debate continues - What is the role of MCU and mitochondrial calcium uptake in the heart? |
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