Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes

scientific article published on 02 July 2007

Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1200/JCO.2006.10.0784
P698PubMed publication ID17606971

P50authorSandra M. SwainQ37839297
P2093author name stringJennifer A Low
James J Lee
Seth M Steinberg
Sherry X Yang
Catherine K Chow
Janice M Walshe
Neelima Denduluri
Arlene W Berman
Ujala Vatas
P2860cites workGenomic signatures to guide the use of chemotherapeutics.Q34576027
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectixabepiloneQ11711607
metastatic breast cancerQ12859063
phase II clinical trialQ42824440
P304page(s)3421-3427
P577publication date2007-07-02
P1433published inJournal of Clinical OncologyQ400292
P1476titlePhase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes
P478volume25

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cites work (P2860)
Q58599310A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model
Q43152531A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma
Q33387547A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: an Eastern Cooperative Oncology Group Trial
Q24615262Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer
Q35975007Advancements in the Treatment of Metastatic Breast Cancer (MBC): The Role of Ixabepilone
Q33999018Beyond taxanes: a review of novel agents that target mitotic tubulin and microtubules, kinases, and kinesins.
Q26865369Beyond taxanes: the next generation of microtubule-targeting agents
Q83329362Clinical studies with epothilones
Q36245461Current approaches to the management of Her2-negative metastatic breast cancer
Q26865654Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets
Q47388453Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor
Q64991024Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora.
Q34611801Ixabepilone (ixempra), a therapeutic option for locally advanced or metastatic breast cancer.
Q28534786Ixabepilone administered weekly or every three weeks in HER2-negative metastatic breast cancer patients; a randomized non-comparative phase II trial
Q37356274Ixabepilone as monotherapy or in combination for the treatment of advanced breast cancer
Q34788890Ixabepilone as monotherapy or in combination with capecitabine for the treatment of advanced breast cancer
Q34417996Ixabepilone development across the breast cancer continuum: a paradigm shift
Q46173239Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: a phase 2 study of the Department Of Defense Prostate Cancer Clinical Trials Consortium
Q34180965Ixabepilone-associated peripheral neuropathy: data from across the phase II and III clinical trials
Q34562783Ixabepilone-induced mitochondria and sensory axon loss in breast cancer patients
Q37290709Ixabepilone: a new chemotherapeutic option for refractory metastatic breast cancer
Q28298312Ixabepilone: a novel microtubule-stabilizing agent for the treatment of metastatic breast cancer
Q37563451Ixabepilone: in locally advanced or metastatic breast cancer
Q36714374Locoregional interaction of ixabepilone (ixempra) after breast cancer radiation
Q37403186Management of advanced breast cancer with the epothilone B analog, ixabepilone
Q53271035Mitosis is not a key target of microtubule agents in patient tumors.
Q37057994New therapeutic options for chemotherapy-resistant metastatic breast cancer: the epothilones.
Q34611212Novel microtubule-targeting agents - the epothilones.
Q37321909Novel neurosensory testing in cancer patients treated with the epothilone B analog, ixabepilone
Q34636002Novel therapies for metastatic renal cell carcinoma: efforts to expand beyond the VEGF/mTOR signaling paradigm
Q34204598Optimizing ixabepilone treatment schedules in patients with advanced or metastatic breast cancer
Q33384027Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consort
Q37104791Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors
Q61624734Phase I trial of dasatinib and ixabepilone in patients with solid tumors
Q36988082Phase I trial of ixabepilone administered as three oral doses each separated by 6 hours every 3 weeks in patients with advanced solid tumors
Q34307937Phase I trial of ixabepilone plus pegylated liposomal doxorubicin in patients with adenocarcinoma of breast or ovary
Q30433670Phase II clinical trial of ixabepilone in patients with recurrent or persistent platinum- and taxane-resistant ovarian or primary peritoneal cancer: a gynecologic oncology group study
Q34915389Phase II trial of ixabepilone administered daily for five days in children and young adults with refractory solid tumors: a report from the children's oncology group
Q34274925Present and future evolution of advanced breast cancer therapy
Q35847455Randomized Phase III Trial of Paclitaxel Once Per Week Compared With Nanoparticle Albumin-Bound Nab-Paclitaxel Once Per Week or Ixabepilone With Bevacizumab As First-Line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/NC
Q37950515Recent developments in treatment stratification for metastatic breast cancer
Q35076330Synergistic activity of ixabepilone plus other anticancer agents: preclinical and clinical evidence
Q34587678The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies
Q37791482The microtubule as a breast cancer target
Q37207961Treatment options for breast cancer resistant to anthracycline and taxane
Q42621663Two schedules of etirinotecan pegol (NKTR-102) in patients with previously treated metastatic breast cancer: a randomised phase 2 study
Q37350227Update on medication-induced peripheral neuropathy

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