Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting

scientific article published on 01 March 2001

Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0925-4773(00)00573-6
P698PubMed publication ID11231066

P50authorLaura MilliganQ42579213
P2093author name stringC Brunel
E Antoine
G Cathala
T Forné
M Weber
A Delalbre
P2860cites workFunctional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitiveQ74014247
Parental imprinting of the mouse H19 geneQ22122365
Genomic sequencingQ24594942
Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated proteinQ28117051
The protein CTCF is required for the enhancer blocking activity of vertebrate insulatorsQ28142800
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 geneQ28145754
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locusQ28145756
An enhancer deletion affects both H19 and Igf2 expressionQ28288348
Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and transQ28594559
Role for DNA methylation in genomic imprintingQ29618669
Dynamics of DNA methylation patternQ33885052
Active demethylation of the paternal genome in the mouse zygoteQ33901068
Identification of a methylation imprint mark within the mouse Gnas locusQ33964982
The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.Q34059933
Igf2 imprinting does not require its own DNA methylation or H19 RNA.Q35205921
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Q35211749
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2.Q36820044
Two regulatory domains flank the mouse H19 geneQ36848651
Dynamic methylation adjustment and counting as part of imprinting mechanismsQ37518550
A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout developmentQ40022869
Specific endonucleolytic cleavage of IGF-II mRNAsQ41664840
Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.Q41979401
Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function.Q47590866
Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.Q48125063
Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript familyQ48264430
Bisulfite sequencing in preimplantation embryos: DNA methylation profile of the upstream region of the mouse imprinted H19 geneQ48933258
A paternal-specific methylation imprint marks the alleles of the mouse H19 geneQ49057890
Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19.Q52164786
Imprinting mechanisms in mammals.Q52187194
Genomic imprinting. Silence across the border.Q52579639
H19 gene expression is up-regulated exclusively by stabilization of the RNA during muscle cell differentiation.Q53900112
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Epigenetic mechanisms underlying the imprinting of the mouse H19 geneQ72094721
P433issue1-2
P304page(s)133-141
P577publication date2001-03-01
P1433published inMechanisms of DevelopmentQ6804657
P1476titleExtensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting
P478volume101

Reverse relations

cites work (P2860)
Q73826779A real-time polymerase chain reaction assay for quantification of allele ratios and correction of amplification bias
Q33318984Aberrant epigenetic changes and gene expression in cloned cattle dying around birth
Q36328828Allele-specific demethylation at an imprinted mammalian promoter
Q37251251Alterations in methylation and expression levels of imprinted genes H19 and Igf2 in the fetuses of diabetic mice
Q47273848An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues.
Q33757992An intragenic methylated region in the imprinted Igf2 gene augments transcription.
Q41904366Characterisation of the methylation pattern in the intragenic CpG island of the IGF2 gene in Bos taurus indicus cumulus cells during in vitro maturation
Q29618090Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
Q34241822Corneal transduction by intra-stromal injection of AAV vectors in vivo in the mouse and ex vivo in human explants.
Q36521372DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice
Q64105137Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations
Q36499262Expression of KCNQ1OT1, CDKN1C, H19, and PLAGL1 and the methylation patterns at the KvDMR1 and H19/IGF2 imprinting control regions is conserved between human and bovine
Q34986939Genomic imprinting controls matrix attachment regions in the Igf2 gene
Q36283370Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice.
Q34291425H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts
Q41561078Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals
Q34473768Intronic parent-of-origin dependent differential methylation at the Actn1 gene is conserved in rodents but is not associated with imprinted expression
Q35153510Long-range chromatin interactions at the mouse Igf2/H19 locus reveal a novel paternally expressed long non-coding RNA.
Q50640391Methylation analysis of the intergenic differentially methylated region of DLK1-GTL2 in human.
Q37145622No evidence for parental imprinting of mouse 22q11 gene orthologs
Q34358824Promoter-specific expression and imprint status of marsupial IGF2

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