Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility

scientific article published on 13 February 2019

Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.26508/LSA.201800276
P932PMC publication ID6374992
P698PubMed publication ID30760555

P50authorYoshifumi ItohQ58809398
Pia Pernille SøgaardQ91556725
Karl MatterQ43165892
P2093author name stringYasuyuki Fujita
Noriko Ito
Nanami Sato
P2860cites workThe binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils.Q51139990
Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility.Q52594536
Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1.Q53891366
DDR1 signaling is essential to sustain Stat5 function during lactogenesisQ81225446
The discoidin domain receptor tyrosine kinases are activated by collagenQ24313329
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cellsQ24678887
Two distinct integrin-mediated mechanisms contribute to apical lumen formation in epithelial cellsQ27343136
Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase InhibitorQ27679284
Membrane-type matrix metalloproteinases: Their functions and regulationsQ28085194
The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cellsQ28207209
Transmembrane collagen receptorsQ28237498
An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptorsQ28276070
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteinsQ28276992
Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarityQ28385568
Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland developmentQ28589694
Par3 functions in the biogenesis of the primary cilium in polarized epithelial cellsQ30441567
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Q30497855
DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherinQ30499285
A molecular switch for the orientation of epithelial cell polarizationQ30603108
Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts.Q33586567
Discoidin domain receptor functions in physiological and pathological conditionsQ33611605
Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimersQ33848736
Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase.Q33880837
FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells.Q34583202
A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration.Q34661632
Opinion: Building epithelial architecture: insights from three-dimensional culture modelsQ34718096
Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.Q34737879
ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1).Q35077020
Collagen recognition and transmembrane signalling by discoidin domain receptorsQ35094710
Functional analysis of tight junctionsQ35150365
Mouse Mammary Epithelial Cells form Mammospheres During Lactogenic DifferentiationQ35187319
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMPQ35191039
MT1-MMP: a tethered collagenaseQ35770291
Prolactin regulation of beta-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell lineQ35982554
Golgi positioning: are we looking at the right MAP?Q36076559
The polarized distribution of an apical cell surface glycoprotein is maintained by interactions with the cytoskeleton of Madin-Darby canine kidney cellsQ36220951
ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrixQ36324827
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3.Q36328263
Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironmentQ36433767
Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein SignalingQ36489242
LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.Q36841533
Three-dimensional cultures of mouse mammary epithelial cellsQ36883681
The RhoA-Rok-myosin II pathway is involved in extracellular matrix-mediated regulation of prolactin signaling in mammary epithelial cellsQ36910229
An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epitheliumQ36981654
DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis.Q37400161
Organization and execution of the epithelial polarity programmeQ38197884
Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transferQ39489538
Analysis of MMP-dependent cell migration and invasion.Q39743200
DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading.Q39846359
Discoidin domain receptor 1 activation suppresses alpha2beta1 integrin-dependent cell spreading through inhibition of Cdc42 activity.Q39941792
Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesisQ40001095
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
Function of discoidin domain receptor I in HGF-induced branching tubulogenesis of MDCK cells in collagen gel.Q40507307
Rac1 orientates epithelial apical polarity through effects on basolateral laminin assemblyQ40782515
Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasivenessQ41038711
Role of calcium in tight junction formation between epithelial cellsQ41712997
Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrixQ42024098
The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA.Q42800404
Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis.Q46366404
Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells.Q47132771
Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cellsQ47921771
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)e201800276
P577publication date2019-02-13
P1433published inLife Science AllianceQ73908590
P1476titleEpithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility
P478volume2

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