scholarly article | Q13442814 |
P50 | author | Balapal S Basavarajappa | Q44392579 |
P2093 | author name string | Shivakumar Subbanna | |
P2860 | cites work | Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity | Q21135310 |
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JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist | Q34098234 | ||
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Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies | Q48301733 | ||
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on "tetrad", sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies. | Q48569237 | ||
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor. | Q48658239 | ||
Effect of JWH-250, JWH-073 and their interaction on "tetrad", sensorimotor, neurological and neurochemical responses in mice | Q48970084 | ||
Functional effects of synthetic cannabinoids versus Δ9 -THC in mice on body temperature, nociceptive threshold, anxiety, cognition, locomotor/exploratory parameters and depression | Q50052091 | ||
ACPA and JWH-133 modulate the vascular tone of superior mesenteric arteries through cannabinoid receptors, BKCa channels, and nitric oxide dependent mechanisms. | Q50057295 | ||
The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis | Q50151709 | ||
AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice | Q34223229 | ||
1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice | Q34236794 | ||
Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphorylated CREB-Bcl-2 pathway after subarachnoid hemorrhage in rats. | Q34325190 | ||
The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse | Q34336690 | ||
Schedules of controlled substances: temporary placement of four synthetic cannabinoids into Schedule I. Final order | Q34408874 | ||
CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression | Q34412161 | ||
Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists | Q34453695 | ||
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice | Q34581274 | ||
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat. | Q34602111 | ||
Qualitative confirmation of 9 synthetic cannabinoids and 20 metabolites in human urine using LC-MS/MS and library search | Q34607414 | ||
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications | Q34617484 | ||
Long lasting consequences of cannabis exposure in adolescence | Q34764034 | ||
JWH-018 and JWH-073: Δ⁹-tetrahydrocannabinol-like discriminative stimulus effects in monkeys | Q35650744 | ||
Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market | Q35836423 | ||
Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions | Q35887816 | ||
Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice | Q36409544 | ||
Toxicokinetics of drugs of abuse: current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine | Q36508621 | ||
Analysis of tolerance and behavioral/physical dependence during chronic CB1 agonist treatment: effects of CB1 agonists, antagonists, and noncannabinoid drugs | Q36573225 | ||
Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors | Q36938493 | ||
Neuronal expression of CB2 cannabinoid receptor mRNAs in the mouse hippocampus | Q37029175 | ||
Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles | Q37397048 | ||
Diuretic effects of cannabinoid agonists in mice | Q37413414 | ||
A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors | Q37578979 | ||
CB1 receptor-mediated signaling underlies the hippocampal synaptic, learning, and memory deficits following treatment with JWH-081, a new component of spice/K2 preparations | Q37648995 | ||
Potency trends of Δ9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008. | Q38431693 | ||
Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice. | Q38616780 | ||
MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors | Q38902712 | ||
Investigation of the in vitro toxicological properties of the synthetic cannabimimetic drug CP-47,497-C8. | Q39009725 | ||
Effects of a novel CB1 agonist on visual attention in male rats: role of strategy and expectancy in task accuracy | Q39121700 | ||
The central neuropharmacology of psychotropic cannabinoids | Q39632100 | ||
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. | Q39653751 | ||
Deletion of CB2 cannabinoid receptors reduces synaptic transmission and long-term potentiation in the mouse hippocampus | Q40216225 | ||
The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. | Q40290354 | ||
JWH-018 impairs sensorimotor functions in mice. | Q40926033 | ||
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice | Q41227667 | ||
AM1241 alleviates MPTP-induced Parkinson's disease and promotes the regeneration of DA neurons in PD mice | Q42366580 | ||
Behavioral responses to acute and sub-chronic administration of the synthetic cannabinoid JWH-018 in adult mice prenatally exposed to corticosterone. | Q50542166 | ||
Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings. | Q52301471 | ||
The CB(1) cannabinoid receptor juxtamembrane C-terminal peptide confers activation to specific G proteins in brain. | Q52537508 | ||
Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA. | Q52651312 | ||
Repeated Exposure to the "Spice" Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats. | Q52657192 | ||
Synthetic cannabinoids found in "spice" products alter body temperature and cardiovascular parameters in conscious male rats. | Q53094148 | ||
Cannabinoid type 2 receptors mediate a cell type-specific self-inhibition in cortical neurons | Q56966579 | ||
A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats | Q57461950 | ||
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ-THC | Q57491573 | ||
Behavioral and Pharmacokinetic Profile of Indole-Derived Synthetic Cannabinoids JWH-073 and JWH-210 as Compared to the Phytocannabinoid Δ-THC in Rats | Q58573307 | ||
Pharmacodynamic Effects, Pharmacokinetics, and Metabolism of the Synthetic Cannabinoid AM-2201 in Male Rats | Q59797649 | ||
Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants. | Q64904627 | ||
The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor | Q73091531 | ||
Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes | Q77341707 | ||
The synthetic cannabinoid 5F-AMB changes the balance between excitation and inhibition of layer V pyramidal neurons in the mouse medial prefrontal cortex | Q88955716 | ||
Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2 | Q90015321 | ||
Synthetic cannabinoid, JWH-030, induces QT prolongation through hERG channel inhibition | Q90844573 | ||
Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice | Q93015114 | ||
Cannabinoid-like effects of five novel carboxamide synthetic cannabinoids | Q93138753 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cannabinoids | Q422936 |
CNRs [plasma membrane] | Q50272675 | ||
P304 | page(s) | 14 | |
P577 | publication date | 2019-01-16 | |
P1433 | published in | Brain Sciences | Q27724596 |
P1476 | title | Potential Mechanisms Underlying the Deleterious Effects of Synthetic Cannabinoids Found in Spice/K2 Products | |
P478 | volume | 9 |